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Tardyferon B9 contains iron, folic acid used to prevent iron deficiency and folic acid during pregnancy when the diet is not enough. Tardyferon B9 should not be used for primary prevention of congenital neural tube defects.
1. What is Tardyferon B9?
Tardyferon B9 has the composition of: iron 50mg (available in the form of iron II sulfate dried 154,530 mg), folic acid (anhydrous) 0.350 mg and excipient system: maltodextrin, microcrystalline cellulose, triethyl citrate, talc , ammonio methacrylate copolymer dispersion type B and type A, glycerol dibehenate...Iron is an essential component for the formation of hemoglobin, an adequate supply of iron will help in red blood cell production and efficient blood oxygen transport. best. When iron is added through food or when taken as a supplement, iron passes through the intestinal mucosa as iron II and binds to a carrier protein and then travels through the body to the bone marrow to form red blood cells.
Folic acid belongs to group B vitamins, when entering the body, folic acid is reduced to tetrahydrofolate. It is an essential coenzyme in the synthesis of purine and pyrimidine leading to DNA synthesis.
2. Indications of the drug Tardyferon B9
Tardyferon B9 good ? Tardyferon B9 is a product of Pierre Fabre Company (France) in the form of extended-release tablets. Iron salts are usually poorly absorbed, only about 10-20% of an oral dose is absorbed into the body. The gradual release of iron in the form of Tardyferon B9 extended-release tablets will increase absorption over time.
Tardyferon B9 is used to prevent iron and folic acid deficiency during pregnancy when pregnant women cannot ensure an adequate diet. Tardyferon B9 should not be used for primary prevention of the risk of congenital neural tube defects (spina bifida).
Dosage of Tardyferon B9 daily take 1 tablet containing 50mg of iron and 0.350mg of folic acid in the last 2 trimesters of pregnancy (start using the drug from the 4th month of pregnancy).
Tardyferon B9 tablets are taken orally, swallow whole, do not suck, chew or keep Tardyferon B9 tablets in your mouth, take the drug before meals with a full glass of water. The duration of taking Tardyferon B9 can be adjusted depending on the tolerability of the digestive organs of each specific subject.
3. Contraindications of Tardyferon B9
Do not use Tardyferon B9 in the following cases:
History of allergy to one of the components of Tardyferon B9; Patients with iron overload.
4. Warnings and Precautions for Tardyferon B9
Due to the risk of mouth ulcers and tooth discoloration of Tardyferon B9, patients should not suck, chew or keep Tardyferon B9 tablets in their mouths, they should be swallowed whole with a full glass of water.
Besides, drinking a lot of tea (tea) can inhibit the absorption of iron contained in Tardyferon B9. Therefore, Tardyferon B9 should not be used at the same time as this drink. In particular, you need to keep Tardyferon B9 out of the reach and sight of children.
5. Tardyferon B9 . side effects
Tardyferon B9 may cause a number of possible side effects, classified in decreasing frequency. Common side effects of Tardyferon B9 (1 - 10 patients per 100 users)
Constipation; Diarrhea ; Distention; Stomachache; Change in stool color; Nausea Uncommon side effects of Tardyferon B9 (1 - 10 patients per 1000 users)
Laryngeal edema; Abnormal stool characteristics; Undigested; Vomit; Gastritis; Itchy; Redness of the skin. Tardyferon B9 side effects are not estimated to occur in frequency:
Change in tooth color; Ulcers in the mouth; Allergic reaction; Urticaria (skin swelling, itching); Temporary discoloration of teeth when using Tardyferon B9 medicine improperly, such as crushing Tardyferon B9 tablets, sucking or keeping Tardyferon B9 tablets for a long time in the mouth; Administration of Tardyferon B9 to elderly patients or patients with swallowing disorders may increase the risk of esophageal injury or bronchial necrosis when the drug enters the wrong way.
6. Interaction of Tardyferon B9 with other drugs
Combination not recommended when using Tardyferon B9:
Do not combine with Iron (salt form) (for injection) because it can cause fainting, even shock because iron is rapidly released from the complex and saturated form. transferrin. Coordination should be noted when using Tardyferon B9
Because iron ions inhibit the absorption of oral cyclins, it is necessary to avoid taking Tardyferon B9 concomitantly with cyclins or taking Tardyferon B9 with an appropriate interval of about 2 days from cyclins. hours; Increased risk of D-penicillamine toxicity when iron therapy is discontinued; The phenomenon of reduced iron absorption when Tardyferon B9 is used concurrently with cytoprotective agents, so it is necessary to use Tardyferon B9 with an appropriate interval of 2 hours from antacids; To avoid possible drug interactions between Tardyferon B9 and many other drugs, especially parenteral iron salts, it is necessary to inform the doctor or pharmacist of any other medications the patient is currently taking. .
7. Use Tardyferon B9 for pregnant and lactating women
According to the results of clinical trials on thousands of pregnant women using Tardyferon B9, almost iron sulfate has no harmful effects on both the mother and the fetus in the womb. Therefore, under normal conditions, Tardyferon B9 can be prescribed to pregnant women for use during pregnancy.
No assessment has been made on whether ferrous sulfate is excreted in human milk, however, based on the nature of the drug, Tardyferon B9 can be used by breastfeeding women.
8. Overdose of Tardyferon B9
After ingestion of large amounts of Tardyferon B9 by mistake, cases of overdose with iron salts have been reported, especially in children under 2 years of age with symptoms including: signs of necrosis and gastrointestinal irritation. , vomiting, nausea and shock in the majority of cases of Tardyferon B9 overdose;
Management of Tardyferon B9 overdose must be initiated as soon as possible, including gastric lavage with 1% sodium bicarbonate solution;
Treatment using chelating agents can be effective, the most effective agents being deferoxamine, mainly used when serum iron levels are greater than 4 μg/ml. Shock, dehydration, and acid-base imbalance should be treated using conventional methods.
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