What is Stafloxin?

This is an automatically translated article.

Stafloxin 200 is a product licensed by the Drug Administration of Vietnam - the Ministry of Health with the main use being to treat diseases caused by sensitive bacteria such as gonorrhea, prostatitis, acute bacterial infections. .

1. What is Stafloxin 200mg?


Stafloxin 200 is a drug to treat systemic infections with the main ingredient being Ofloxacin, a carboxylic acid derivative of the Quinolone group, which has broad-spectrum antibacterial properties. Stafloxin 200 is available as a film-coated tablet for oral administration.
Stafloxin 200 is indicated for use in the following cases:
Skin and soft tissue infections. Prostatitis ; Uncomplicated cervical/urethral gonococcal infection; Urinary tract infections; Patients with impaired renal function; Acute bacterial exacerbation of chronic bronchitis ; Cervicitis/urethritis not due to gonorrhea.

2. Instructions for using Stafloxin


Stafloxin 200 should be used according to the instructions and instructions of the doctor, not arbitrarily used to treat infections at will.
Dosage depends on the condition, the type of infection as well as the progression of the disease. Patients can refer to the dosage below:
Treatment of uncomplicated cervical and urethral gonorrhea: Take a single dose of 400mg (2 tablets); Prostatitis treatment: 300mg every 12 hours for 6 weeks; Treatment of skin and soft tissue infections: Oral 400mg (2 tablets) x 2 times/day; Treatment of cervicitis and non-gonococcal urethritis: Oral 400mg (2 tablets)/day single dose or divided dose; Treatment of urinary infections: Oral 200-400mg (1-2 tablets)/day, if necessary, increase the dose to 400mg (2 tablets) x2 times/day; Acute bacterial exacerbation of chronic bronchitis: Take 400mg (2 tablets)/day, if necessary, the dose can be increased to 400mg (2 tablets) x 2 times/day. *Note:
Particularly for patients with impaired renal function, after the usual starting dose should reduce the therapeutic dose; The usual duration of treatment is 5-10 days (except for uncomplicated gonorrhea with single dose). The duration of treatment with Stafloxin 200 should not exceed 02 months; Medicines are taken orally, the best time to take them is in the morning; Swallow the tablet whole, do not chew or crush the tablet.

Thuốc Stafloxin 200 là thuốc điều trị nhiễm khuẩn toàn thân với thành phần chính là Ofloxacin
Thuốc Stafloxin 200 là thuốc điều trị nhiễm khuẩn toàn thân với thành phần chính là Ofloxacin

3. Stafloxin side effects


During the use of Stafloxin 200, there may be some side effects such as:
Gastrointestinal reactions: Nausea and vomiting, abdominal pain, diarrhea; Nervous reactions: Dizziness headache, fatigue, tremor, drowsiness, insomnia, nightmares, visual disturbances; Skin reactions: Rash, itching, hypersensitivity; In addition, there are also some serious and potentially irreversible and disabling adverse reactions such as tendonitis, tendon rupture, peripheral neuropathy, and adverse effects on the central nervous system. nurse.
If unusual signs occur, immediately contact a doctor or go to the nearest medical center for help.

4. Note when using Stafloxin


To avoid unwanted side effects, Stafloxin 200 is contraindicated in the following subjects:
People with a history of tendonitis; People with a history of epilepsy (or with a low seizure threshold); Patients with hypersensitivity to other quinolones or to any of the excipients; Women who are pregnant or breastfeeding; Children and adolescents are growing; Patients with deficiency or at risk of glucose-6-phosphate dehydrogenase deficiency. At the same time, use the drug with caution in the following cases:
Patients with renal failure; The patient has a history of psychiatric or neurological disorders. *Note: Avoid fluoroquinolone antibiotics in patients who have experienced serious fluoroquinolone-related reactions. Stop taking Stafloxin 200 at the first sign or symptom of any serious adverse reaction. Immediately discontinue treatment with Ofloxacin if signs of:
First sign of hypersensitivity reaction; Inflammation, pain, or rupture of tendons. You need to rest, limit movement until the condition improves.

Buồn nôn và nôn là tác dụng phụ của thuốc Stafloxin
Buồn nôn và nôn là tác dụng phụ của thuốc Stafloxin

5. Stafloxin drug interactions


Antacids, oral iron and Sucralfate may reduce the absorption of Ofloxacin; Stafloxin 200 may increase the effect of the anticoagulants Warfarin and Acenocoumarol and increase the risk of bleeding. Therefore, it is necessary to check the INR regularly. It may be necessary to adjust the dose of anticoagulants during treatment with Stafloxin and after treatment is discontinued. In general, Stafloxin 200 has the advantage of effective treatment of inflammatory conditions such as bronchitis, urinary tract infections, cervicitis ... However, the drug has the disadvantage that it can cause tendonitis, tendon rupture. no recovery and some other side effects. Therefore, it should not be used by pregnant and lactating women.
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