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Stadnex 20 cap is an gastrointestinal medication containing esomeprazole. Stadnex 20 is commonly used to treat gastroesophageal reflux disease, peptic ulcer disease caused by NSAID use, and duodenal ulcer caused by Helicobacter pylori bacteria. In addition, it is also used to treat Zollinger-Ellison syndrome.
1. What is Stadnex 20 cap?
Stadnex 20 is known as a brand name that contains 20mg of Esomeprazole, a proton pump inhibitor to reduce gastric acid secretion. Thanks to its specific action on the proton pump, esomeprazole can block the final step in acid production, which then reduces gastric acidity. This effect is dose dependent from 20 to 40 mg daily and leads to inhibition of gastric acid secretion.
Thanks to the inherent uses, Stadnex 20 is indicated for the following cases:
Gastroesophageal reflux disease: Treatment of esophagitis caused by reflux; long-term healing esophagitis to prevent recurrence; symptoms of gastroesophageal reflux disease - esophagitis; In combination with an appropriate antibacterial regimen to destroy Helicobacter pylori, treat duodenal ulcers caused by Helicobacter pylori infection and prevent recurrence of peptic ulcer disease in patients with Helicobacter pylori infection; Patients must use non-steroidal anti-inflammatory drugs (NSAIDs) continuously: Treatment of stomach ulcers caused by NSAID drugs; prevention of gastric and duodenal ulcers associated with NSAID use in certain at-risk patients; Treatment of Zollinger-Ellison syndrome.
2. Instructions on how to take Stadnex 20
How to take Take the tablet whole with a little clean water. Do not chew or crush the medicine.
Dosage Adults and children ≥ 12 years old Reflux esophagitis: 2v (40 mg) x 1 time/day x 4 weeks. If esophagitis has not healed or has persistent symptoms, another 4 weeks of treatment is needed.
Long-term treatment of healed esophagitis to prevent recurrence: 1v (20 mg) x 1 time/day.
Symptomatic treatment of gastroesophageal reflux disease (GERD): 1v (20 mg) x 1 time/day for patients without esophagitis.
If symptoms are not controlled after 4 weeks, the patient should be further diagnosed.
Once symptoms are gone, symptom control can be maintained with a daily dose of 1v (20 mg) x 1 time/day.
In patients with gastroesophageal reflux disease (GERD) who are taking NSAIDs at risk of developing peptic ulcers, it is not recommended to control symptoms with a regimen.
Adults In combination with an appropriate antibacterial regimen to eradicate Helicobacter pylori and prevent recurrence of peptic ulcers caused by Helicobacter pylori infection: 1v (20 mg) + 1g amoxicillin + 500mg clarithromycin x 2 times/day x 1 week .
Treatment of stomach ulcers caused by the use of NSAIDs: 1v (20 mg) x 1 time / day x 4 - 8 weeks.
Prophylaxis of gastric - duodenal ulcers caused by NSAID use in patients at risk: 1v (20 mg) x 1 time/day.
Zollinger - Ellison syndrome:
Initial dose: 2v (40 mg) x 2 times/day, then adjust dose as required. Maintenance dose: 4 - 8v (80 - 160 mg)/day (dose > 80mg/day should be divided into 2 doses). Children < 12 years: Not recommended.
Patients with impaired or damaged liver function:
No dose adjustment is required in mild-moderate patients. The maximum dose for patients with severe liver failure is 1 tablet (20 mg).
Elderly sick: No dose adjustment is required. Note: Stadnex 20 dosage above is for reference only. The specific dose of Stadnex 20 must depend on the patient's condition and the course of the disease. For the proper dose of the drug, consult your doctor or healthcare professional.
3. Side effects of Stadnex 20
During treatment with Stadnex 20, users may experience the following unwanted symptoms:
Common (> 1%)
Dizziness, headache, skin rash. Nausea, vomiting, abdominal pain, diarrhea, flatulence, constipation, dry mouth. Note: During the use of Stadnex 20, if any of the above symptoms or other symptoms are suspected, stop taking the drug and contact your doctor or pharmacist immediately.
4. Note when using Stadnex 20
Contraindicated to use Stadnex 20 in the following cases:
Hypersensitivity to esomeprazole, benzimidazole derivatives or any of the ingredients in the drug. Pregnant women in the first 3 months. Other Precautions
Stadnex 20 may relieve symptoms or delay the diagnosis of malignancies so if any of these symptoms are present (such as unintentional weight loss, vomiting blood, black stools, difficulty in passing). swallowing...) need to contact a doctor for correct treatment. Proton pump drugs should be used with caution, especially when used in high doses and for a long time (> 1 year) which may increase the risk of fractures of the femoral neck, wrist and spine, in the elderly or in the elderly. having other risk factors increases the risk. Treatment with proton pump inhibitors may slightly increase the likelihood of gastrointestinal infections due to Salmonella and Campylobacter. Stadnex 20 may reduce the absorption of vitamin B12 due to a lack of hydrochloric acid in the gastric juice. Stadnex 20 causes symptomatic or absent hypomagnesemia when taken for at least 3 months, mostly for more than 1 year. Serious side effects include muscle spasticity, arrhythmias, and seizures. Patients treated with esomeprazole should have their serum magnesium levels monitored from the start, and if hypomagnesemia is detected, magnesium supplementation or discontinuation of the drug should be considered. In addition, taking Stadnex 20 may cause dizziness or hallucinations, so do not drive or operate machinery while taking this medicine.
5. Interactions of Stadnex 20
Be careful when using drugs containing the following substances with Stadnex 20 to avoid unwanted side effects:
Ketoconazole, iron salts, Digoxin; Clarithromycin and Amoxicillin; Atazanavir 300mg/ Ritonavir 100mg; Drugs metabolised via CYP2C19; Warfarin. The above is all important information when using Stadnex 20, patients need to understand for the treatment to be effective as well as less likely to experience side effects to health.
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