Mucosta has the active ingredient rebamipide, which is a prescription drug that acts as a protective agent for gastrointestinal mucosal cells. Accordingly, the use of Mucosta is used in the treatment of gastric ulcers and gastritis. The following information is necessary before taking the drug and to monitor during treatment.
1. What is Mucosta?
Mucosta is the brand name of the active ingredient rebamipide. This is an amino acid derivative of 2-(1H)-quinolinone, used to protect the mucosa, heal gastric and duodenal ulcers and treat gastritis. The mechanism of action of the drug is by enhancing mucosal protection, scavenging free radicals and temporarily activating genes encoding cyclooxygenase-2.
Several studies have shown that rebamipide can counteract the harmful effects of non-steroidal anti-inflammatory drugs (NSAIDs) on the gastrointestinal mucosa, including the small intestine. However, the drug's ability to protect against gastric damage caused by naproxen has not been clearly demonstrated.
2. What is the use of Mucosta?
Mucosta or rebamipide has the main ingredient available in both oral and ophthalmic forms. The oral form of this drug acts as a mucosal protectant and is used to treat ulcers in the stomach and intestines in adult patients. The ophthalmic form of this drug is used to treat dry eyes. In particular, the effect on the digestive tract plays a major role in the use of Mucosta. Therefore, the indications of rebamipide are prescribed for the treatment of gastric ulcers, duodenal ulcers and gastric disorders including the following:
Indicated in cases of bleeding, erosion, inflammation and edema or all signs of damage to the gastric mucosa in general, occurring in the context of acute gastritis and acute exacerbation of chronic gastritis. Indicated as an effective and safe drug in the treatment of recurrent oral mucosal ulcers in Behcet's disease.
3. How is Mucosta dosed?
Mucosta is prepared in the form of tablets with the active ingredient rebamipide, the content of 100 mg can be prescribed in adults as 1 tablet per dose and taken three times a day.
The best times to take the medication for optimal results are in the morning, afternoon and evening before bedtime.
4. What should be noted when using Mucosta?
Before starting to use the drug, the physician or clinical pharmacist needs to inform the patient of the following notes when using Mucosta:
- Because elderly patients may have physiological changes that are sensitive to this drug and are more susceptible to digestive disorders than younger patients, special care should be taken when using the drug on these subjects.
- Only use the drug for pregnant women or women who may become pregnant if the expected therapeutic benefits are believed to outweigh any potential risks associated with pregnancy.
- Breastfeeding should be avoided during the prescribed use of the drug.
- The drug may interact with celecoxib or diclofenac
5. What are the side effects when using Mucosta?
- Side effects when using Mucosta include:
- Itching and skin rash
- Nausea and vomiting
- Dizziness
- Loss of appetite
- Bitter or unusual taste
- Dry mouth
- Blurred vision
- Eye irritation
- Eye discharge
- Constipation
- Flatulence
- Diarrhea
- Epigastric pain
- Heartburn, belching
- Cold sweat
- Shortness of breath
6. What are the monitoring measures when using Mucosta?
Stop using the drug and take the patient immediately to the nearest emergency department if allergic reactions or suspicious signs occur such as difficulty breathing or swallowing, chest tightness, swelling, skin rash and hives.
Patients need to be closely monitored for leukopenia (reduced white blood cells), thrombocytopenia (reduced thrombocyte) and liver dysfunction during treatment with Mucosta.
In summary, Mucosta or rebamipide is an anti-gastric and anti-ulcer drug used to protect the mucosa, heal stomach ulcers, small intestine and treat gastritis. However, the drug can cause unwanted side effects. Therefore, the use of the drug requires a prescription and strict adherence to dosage instructions, so that the drug is both effective and safe for the patient.
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References: practo.com, medindia.net
