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With the main ingredients including potassium aspartate and magnesium aspartate, what is Panangin and what is it indicated for use in? Please refer to the article below to get more useful information about this drug.
1. What is Panangin?
Panangin has ingredients in each film-coated tablet including 140mg anhydrous magnesium aspartate (exists as 175mg of magnesium aspartate.4H2O), equivalent to 11.8mg of Mg2+ and 158mg of anhydrous Potassium aspartate (available as 166.3mg of Potassium aspartate) aspartate.1/2H2O) is equivalent to 36.2 mg K+. In addition to the main active ingredients, Panangin also contains excipients such as Colloidal Anhydrous Silica, Polyvidon, Magnesium Stearate, Talc powder, corn starch, potato starch...
Another dosage form of the drug is a solution. IV infusion (containing 400 mg magnesium aspartate and 452 mg potassium aspartate)
Mg2+ and K+ are intracellular cations that are important in the function of many enzymes, in the macromolecule binding to elements of Cells, mechanism of muscle contraction. Myocardial contraction will be affected by the ratio of the intracellular and extracellular concentrations of ions such as: K+, Ca2+, Na+.
2. Uses of Panangin
Two main active ingredients in Panangin medicine play an extremely important role in many different metabolic processes in the human body, especially in the function of the nervous system, muscle system and cardiovascular system. Panangin is a drug used to treat a number of chronic cardiovascular diseases such as heart failure, post-myocardial infarction conditions. Panangin is also indicated for adjunctive treatment in certain cases of cardiac arrhythmias, hypertension, increased neuromuscular excitability, and muscle spasms.
Prevention and treatment of magnesium deficiency conditions , increase potassium and magnesium requirements, increase consumption of deficient ions, patients lose significant electrolytes. In treatment with cardiac glycosides, Panangin helps to compensate for the decrease in the concentration of K+ and Mg2+ ions of spinal muscle, myocardium, plasma and red blood cells caused by the drug.
Panangin là thuốc gì? Panangin là thuốc được dùng trong bệnh lý tim mạch
3. How to take panangin
What is the dose of panangin? Unless otherwise specified by the doctor, the usual dose of panangin is 1-2 tablets each time, used 3 times a day, in some cases can be increased to 3 tablets each time, used 3 times a day.
Acidity in the digestive system can reduce the effectiveness of Panangin. Therefore, when prescribed this drug, the patient should swallow the tablet whole, do not chew it, and should take it after a meal. If for some reason you have taken more Panangin than directed, stop taking it immediately and consult your doctor.
For injectable panangin: mix 2 syringes in 50-100 ml of 5% glucose solution, intravenously or slow drip infusion at medical facilities as directed by the doctor.
4. Contraindications of Panangin
Contraindications of Panangin are people with a history of hypersensitivity to any of the ingredients in the drug; Patients with acute and chronic renal failure; Addison's disease ; Patients with third-degree AV block; Cardiogenic shock (systolic blood pressure falls below 90mmHg).
Thuốc Panangin cần dùng theo đúng chỉ định của bác sĩ
5. Notes when using Panangin
With a number of diseases that tend to cause hyperkalemia, the additional use of Panangin must be under close medical supervision.
6. Unwanted effects of the drug Panangin
Inform your doctor as soon as you experience any unusual effects when using Panangin (Magnesium side effects: nausea, vomiting, diarrhea, abdominal pain, flatulence, dry mouth, body weakness, feeling sick). fatigue) High doses of Panangin can cause a laxative; There are no in-depth research data on the harmful effects of Panangin when used in pregnant and lactating women; When Panangin is administered intravenously, symptoms associated with hypermagnesaemia may occur.
7. Interactions of Panangin with other drugs
Panangin drug has the ability to inhibit the absorption of oral tetracycline antibiotics, iron salts and sodium fluoride. Therefore, the interval between doses of Panangin and the drugs mentioned above is 3 hours; Concomitant administration of Panangin with potassium-sparing diuretics and/or angiotensin-converting enzyme inhibitors may result in hyperkalemia.
8. What to do in case of an overdose of Panangin?
If Panangin is overdosed, the magnesium and potassium levels in the patient's blood may rise, causing some adverse symptoms. At that time, it is necessary to stop the drug Panangin immediately and treat symptoms (can give intravenous calcium chloride solution 100mg/min, conduct dialysis if necessary).
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