What is Nospaforte?

No spa forte is an antispasmodic medication used to treat smooth muscle spasms in the digestive system such as bile duct illnesses, and urinary tract ailments. Before using the drug, you should thoroughly consider the benefits and hazards with your doctor in order to make an informed decision.

1. What is NoSpaforte?

Nospaforte is an antispasmodic medications that are primarily used to treat smooth muscle spasms in biliary tract illnesses (such as bile duct stones, gallbladder stones, pericholecystitis, cholecystitis, pancreatitis, or cholangitis). Nospaforte can also be used to treat smooth muscle spasms produced by urinary tract illnesses such as ureteral stones, kidney stones, cystitis, pyelonephritis, or bladder spasm pain.

Not only that, but Nospa 80 mg is also used to treat smooth muscle spasms in the digestive system (including gastritis, gastric-duodenal ulcers, pyloric/cardiac spasms, colon hyperstimulation, or enteritis), as well as various gynecological illnesses, such as dysmenorrhea in women.

Chinoin Pharmaceutical & Chemical Works Private Co., Ltd. manufactures No Spa forte in tablet form, which is packaged in two blisters of ten tablets each. Nospaforte tablets include the following major ingredients:

  • The main active ingredient is Drotaverine hydrochloride 80 mg.
  • Other excipients are sufficient for one tablet: corn starch, povidone, lactose, talc, magnesium stearate.

2. Applications of No Spa Forte

Nospaforte's active ingredient, drotaverine, is an isoquinoline derivative that can directly inhibit spasms in smooth muscles. The drug's method of action involves inhibiting the enzyme phosphodiesterase (PDE) IV while increasing the quantity of cAMP, which leads to smooth muscle relaxation by inactivating the enzyme myosin light chain kinase (MLCK).

In fact, phosphodiesterase (PDE) IV is critical in the process of inhibiting smooth muscle contraction. Nospaforte is commonly used to treat hypermotility disorders and smooth muscle spasms in the digestive tract since it selectively inhibits PDE IV.

According to professionals, Nospaforte increases tissue circulation by dilating blood vessels. The medicine is also helpful in all cases of smooth muscle spasms caused by nerves or muscles. Furthermore, the active element drotaverine affects smooth muscles in the biliary tract, digestive system, vascular system, and genitourinary system.

The following are the pharmacokinetic consequences of the active component drotaverine in the medication No-Spa Forte.

  • Absorption: The medication is rapidly and thoroughly absorbed upon injection or oral administration. Drotaverine plasma concentrations reach their peak between 45 and 60 minutes after intake.
  • Drotaverine has a binding affinity for plasma albumin of up to 98%; a little quantity binds to beta-globulin and gamma.
  • Metabolism: The circulatory system metabolizes around 65% of drotaverine in its unaltered form, with the liver processing the remainder.
  • Excretion: The biological half-life of the active component drotaverine is 8-10 hours. After 72 hours, the medication is no longer in the body and is eliminated in around 30% feces and 50% urine.

3. Dosage and How to Use No Spa forte

3.1 Dosage for No Spa forte

Patients must comprehend not only what Nospa 80 mg is, but also the right dosage for their specific illness. The doctor's recommended dosage for No Spa forte is as follows:

  • The typical dose for adults is: Take 1-3 tablets each day, spaced out 2-3 times per day.
  • For children over the age of 12, the usual dose is 1 - 2 pills per day, divided into 1 - 2 times each day.

3.2 How To Use No-Spa Forte

No spa forte is consumed orally. Patients should take the medicine with filtered water and avoid drinking alcohol or other stimulants, as they can diminish the effectiveness of the active ingredient. In addition, you must swallow the entire pill without chewing or crushing it.

3.3 What to do if you overdose or miss a dose of Nospaforte?

When you missed a dose:

  • The patient should take their missed dose as soon as they remember.
  • If the missed dose is too close to the next scheduled dose, skip it and continue taking the drug as planned.
  • Avoid taking two doses of No Spa Forte.

When you overdose:

  • Symptoms of Overdose: No Spa Forte overdoses have not been reported to cause any adverse responses.
  • In the case of a drotaverine overdose and the appearance of aberrant symptoms, the patient should discontinue use of the medication and seek emergency medical attention.

4. Contraindications of taking Nospaforte

Nospaforte shouldn't be used in the following situations:

  • Individuals having a history of drotaverine allergy or hypersensitivity to any of the drug's excipients.
  • Children under the age of 12 should not use nospaforte.
  • Patients with severe heart failure, liver failure, or kidney failure.

5. Some adverse effects from taking No-Spa Forte

No spa forte can cause the following negative effects for patients:

  • Headache and dizziness.
  • Nausea.
  • Insomnia.
  • Low blood pressure.
  • Constipation.
  • Allergic symptoms include itching, redness, and hives.

When any of the aforementioned side effects arise, you must discontinue use of the medicine and contact your doctor so that you can receive prompt treatment.

6. Interactions with No Spa Forte

When used with Levodopa, Nospaforte can diminish the effectiveness of anti-Parkinson's disease medication and exacerbate symptoms of muscle stiffness and tremors. To reduce the possibility of drug interactions, you should tell your doctor about all of the medications you are taking as well as any other current health issues.

7. Special Notes for Using No Spa Forte

7.1 What precautions should I take when using Nospa forte?

The following are specific subjects that must be cautious when utilizing Nospa 80 mg, including:

  • Patients have low blood pressure.
  • People who are lactose intolerant should exercise caution when taking the medicine because it includes 104 mg of lactose, which can easily cause digestive issues.
  • Pregnant women should see their doctor before taking Nospaforte.
  • Breastfeeding mothers should not take No Spa Forte without a doctor's approval.
  • People who often work in areas that need high attention, such as driving or operating machinery, should exercise caution when taking No Spa Forte because the medicine might cause dizziness as a side effect.

7.2 How should you store No Spa Forte?

Nospaforte should be stored at a temperature below 30 degrees Celsius and away from direct sunlight. In addition, preserve the drug in its original packing and store it in a dry, cold area out of sight and access of youngsters.

When the drug has expired, as indicated on the package, you should not continue to use it. To safeguard the environment, do not dispose of broken medications in household waste or the wastewater system. Instead, check your doctor about how to dispose of expired medications.

Please dial the HOTLINE for more information or to book an appointment HERE. Download the MyVinmec App to book appointments faster and manage your bookings easily.

Share
Patients Stories