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Montiget 10mg is indicated for the treatment of adults in the prevention and treatment of chronic asthma and the relief of symptoms of seasonal and year-round allergic rhinitis. To use the drug correctly and limit the risk of side effects, let's learn about Montiget through the article below.1. What is Montiget?
Montiget drug with the main ingredient Montelukast, is formulated in the form of film-coated tablets. Montiget 5mg has the content of Montelukast 5mg, while the Montiget 10mg tablet has the content of Montelukast 10mg. Montelukast is a selective, competitive antagonist of the leukotriene receptor. Cysteinyl leukotrienes are metabolites of arachidonic acid released from various cells including mast cells and eosinophils. When these metabolites bind to leukotriene receptors, responses include airway edema, bronchial smooth muscle spasm, and altered cellular activity associated with inflammation leading to asthma symptoms. Thus, montelukast competes with cysteinyl leukotrienes for binding to its receptor, without any biological activity.
When using the medicine regularly can occur effects such as:
Prevent wheezing, shortness of breath caused by asthma and help reduce the number of asthma attacks. Reduce symptoms of allergic rhinitis such as sneezing, stuffy nose, runny nose, itchy nose. May be used to treat year-round allergy symptoms in adults and children who are at least 6 months old.
2. Indications and contraindications of Montiget 10mg
Montiget drug is indicated for use in the following cases:
Prevention and treatment of chronic asthma in adults, helping to prevent daytime and nighttime symptoms of asthma. Treatment of patients with asthma due to hypersensitivity to aspirin. Prevents the risk of bronchospasm caused by exercise. For use before the start of exercise to prevent spasms of the anterior respiratory muscles during exercise Treatment of seasonal and year-round allergic rhinitis in adults and children over 2 years of age. Cases of not taking Montiget:
Patients who are allergic to the active ingredient or any of its ingredients. Montelukast is not indicated for use in acute asthma attacks or in patients with severe, persistent asthma that has not responded to conventional therapies.
3. Dosage and how to use Montiget
How to use: Montiget is a film-coated oral tablet, should be taken orally with water.
Dosage;
Adults and adolescents 15 years of age and older with asthma or seasonal allergic rhinitis: The dose is 10mg/day. Dosage for adults to prevent exercise-induced bronchospasm: Take 10mg at least 2 hours before exercise. Children 6-14 years of age with asthma or allergic rhinitis: Take 5mg orally once a day. Children 2 to 5 years old with asthma or allergic rhinitis: Take 4mg tablet once a day; Children 1 to 2 years old with asthma: Take 4mg once a day in the evening; Children from 6 months to 23 months of age with year-round allergic rhinitis: give 4mg once a day. It should be noted that no dose adjustment is necessary in cases including elderly patients, patients with impaired renal function or with mild to moderate impairment of liver function.
4. Side effects of the drug Montiget
When using Montiget, you may experience some unwanted effects including:
Upper respiratory tract infection, diarrhea, nausea and vomiting, increased liver enzymes, rash, fever are common. Uncommon: Anaphylaxis; Abnormal dreams such as nightmares, insomnia, sleepwalking, anxiety, anxiety including agitation or oppositional behavior, depression, hyperactivity; dizziness, drowsiness, convulsions; nosebleeds, dry mouth, indigestion, eyebrow pain, itching, joint pain, cramps; tired, uncomfortable. Rare: Bleeding, attention disorders, memory loss, tachycardia, angioedema. Very rare: Liver eosinophilia, hallucinations, disorientation, suicidal thoughts and behavior; Churg–Strauss syndrome (CSS); Erythema nodosum, erythema multiforme. When experiencing side effects of the drug, you need to stop using it and should notify your doctor or in severe cases you need to go to the nearest medical facility for timely treatment.
5. Notes when using Montiget
Before using the drug you need to tell your doctor about your medical history and carefully read the instructions for use. Never use oral montelukast for treatment during an acute asthma attack and always be prepared with appropriate emergency medication for the condition. If an acute attack occurs, inhaled short-acting drugs should be used. Patients should consult a doctor immediately if they need more inhaled doses than usual. Montelukast should not be used as an abrupt substitute for oral or inhaled corticosteroids. There are currently no data to support the use of oral corticosteroids to reduce dose when used concomitantly with montelukast. In the excipients Montiget contains lactose. Patients with rare problems of galactose intolerance, the Lapp lactase deficiency or malabsorption of this substance should not use this medicine. Pregnancy: Animal studies have not shown adverse effects with regard to pregnancy or fetal/fetal development. Data in pregnant women do not show any causal association between montelukast and fetal malformations. Therefore, Montelukast can be used during pregnancy if the need is clearly weighed against the risk. Lactation: Studies in rats have shown that montelukast is excreted in milk. However, in practice, it is not known whether montelukast and its metabolites are excreted in human milk. Montelukast may be used in lactating women if the obvious need is weighed against the risk to the nursing infant. Drug interactions may occur when other drugs are used concurrently with the use of montelukast in the prevention and chronic treatment of asthma and in the treatment of allergic rhinitis. However, in drug interaction studies, the recommended therapeutic dose of montelukast did not have a significant effect on the pharmacokinetics of drugs including: theophylline, corticosteroids (e.g. prednisolone) oral contraceptives (e.g., prednisolone). ethinyl estradiol/norethindrone 35/1), terfenadine, digoxin and warfarin. But it should be noted when using with drugs that affect the liver, especially in children, when using Montelukast with substances such as Phenytoin, Phenobarbital, Rifampicin. In addition, do not use when the drug shows signs of deterioration, store in a dry place, avoid direct light and moisture, the storage temperature should be below 30 degrees Celsius.
Montiget drug is a prescription drug, used under directed by Doctor. Therefore, you should not self-medicate and always consult your doctor when using.
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