This is an automatically translated article.
Metsav 850 is commonly used in the treatment of non-insulin dependent diabetes. The safe use of drugs will increase the effectiveness of the treatment and vice versa. Refer to the article below to properly understand what metsav 850 is and how to use it properly.
1. What is Metsav 850?
Metsav 850 medicine has the main ingredient is Metformin hydrochloride 850mg. It is used in the treatment of non-insulin dependent diabetes mellitus, also known as type II diabetes mellitus, in monotherapy when the hyperglycemia cannot be treated with diet alone.
Metformin is a biguanide antidiabetic drug, it has a different mechanism of action than sulfonylurea antidiabetic drugs. Metformin does not stimulate insulin release in pancreatic beta cells, and has no hypoglycemic effect in non-diabetic subjects.
In patients with diabetes, metformin will reduce hyperglycemia but not cause hypoglycemic events unless the patient is fasting or the combination of drugs has a synergistic effect. Metformin will reduce plasma glucose concentrations, both fasting and after meals, in patients with type II diabetes. The mechanism of action of metformin is to increase cellular glucose utilization, improve insulin receptor binding and perhaps post-receptor effects, and inhibit hepatic glucose synthesis and decrease absorption. glucose in the intestine.
In addition to its anti-diabetic effect, metformin also somewhat has a beneficial effect on lipoprotein metabolism - a type of metabolism that is often disturbed in patients with type II diabetes.
Thuốc Metsav 850 được dùng trong điều trị bệnh đái tháo đường
2. Indications and contraindications of Metsav 850
2.1. Indications Metsav 850 is indicated in the following cases:
Treatment of type II diabetes in monotherapy when it is not possible to treat hyperglycemia with diet alone. Metsav 850 can be used concomitantly with a sulfonylurea when diet and when Metsav 850 or sulfonylurea drugs alone do not provide adequate glycemic control. 2.2. Contraindications Metsav 850 is contraindicated in the following cases:
Patients with hypersensitivity to the drug components Ketone acidosis Pre-coma with diabetes Renal failure Severe infection Dehydration Shock X-rays associated with the use of contrast Iodine-containing Diseases causing tissue hypoxia such as heart failure, recent myocardial infarction, respiratory failure, shock. Liver failure Acute alcohol intoxication Alcoholics A major surgery program Breastfeeding women, pregnancy. Attention and precautions when using Metsav 850:
Renal failure, liver failure, elderly people, children < 10 years old. Discontinue the drug when there is acute hypoxia, acute heart disease, dehydration, infection.
3. Dosage of Metsav 850 for adults
Start using 1 tablet / time x 1 time / day at breakfast. Increase by 1 tablet/day, once a week, up to a maximum of 2550mg/day. The usual maintenance dose is 1 tablet / time x 2 times / day taken with breakfast and dinner. Some patients can take a dose of 1 tablet / time x 3 times / day at the main meals of the day.
Thuốc Metsav 850 cần được sử dụng đúng liều lượng
4. Side effects when using Metsav 850
When using Metsav 850, patients may experience some side effects as follows:
Digestion: Anorexia, nausea, vomiting, heartburn, epigastric fullness, diarrhea, constipation. Skin: Rash, urticaria, photosensitive. Metabolism: Decreased vitamin B12 levels. Hematology: Blood dysplasia, hemolytic anemia, aplastic anemia, marrow failure, thrombocytopenia, agranulocytosis. Metabolic: Lactic acidosis. When experiencing side effects of Metsav 850, it is necessary to stop using it and notify your doctor or go to the nearest medical facility immediately for timely treatment.
Metsav 850 when used in combination with some other drugs or medicinal herbs can occur. Therefore, when the patient is using some of the following ingredients, it is necessary to inform the doctor to limit the interaction:
Contrast containing iodine Alcohol and alcohol-containing preparations. With caution in combination with Metsav 850 with Glucocorticoids, beta 2 blockers, ACEIs, diuretics.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
