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Gastalo medicine contains the main ingredient L-Ornithin L-Aspartat 500mg. This is a drug with good effects in protecting the liver, treating liver diseases, especially the drug is used in the treatment of hepatic pre-coma or coma.
1. What is Gastalo? What does Gastalo do?
1.1. Indications for treatment of the drug Gastalo Gastalo drug is indicated in the treatment of the following pathologies:
Increased Ammonia in the blood for acute and chronic liver disease (cirrhosis, viral hepatitis, fatty liver, hepatitis etiology). due to drugs, chemicals, alcoholism...); Treatment of the onset disorders of hepatic precoma, hepatic coma and hepatic encephalopathy; Treatment of liver diseases such as hepatic encephalopathy with typical signs and symptoms such as itching, loss of appetite, fatigue, weakness, skin rash due to liver cell failure. 1.2. Pharmacodynamics of the drug Gastalo The main active ingredient is Ornithine L- Aspartate, which has a good effect in enhancing urea synthesis, converting toxic ammonia into urea. The effect is detoxification by reducing ammonia levels in the liver and brain. Laboratory results have demonstrated the effectiveness of reducing blood ammonia by increasing urea synthesis. However, there are still many disagreements about the effect of L-Ornithin L-Aspartate in reducing blood ammonia. Active ingredient L-ornithin-L-aspartate stimulates ammonia detoxification by increasing urea synthesis in the urea cycle. In addition, it also has the effect of removing extrahepatic ammonia from the tissues, thereby detoxifying and protecting liver cells. In addition, the active ingredient L-ornithin-L-aspartate is also used to generate energy in the form of ATP, thereby improving the energy balance of the liver.
1.3. Gastalo Pharmacokinetics The active ingredient L-ornithin-L-aspartate provides two important substrates for both urea and glutamine synthesis. After taking Gastalo 500, the active ingredient L-ornithin-L-aspartate dissociated into L-ornithin and L-aspartic acid, the two substances are then absorbed in the small intestine by active transport across the brush border in the epithelium. small intestine, the absorption of which is dependent on the sodium ion concentration gradient. The bioavailability of Gastalo orally is 82.2 ± 28%. It should be noted that Ornithine is able to cross the blood-brain barrier.
2. How to use and dose of Gastalo
2.1 Gastalo dose: Start taking Gastalo 500mg daily with 3 times, each time taking from 1 to 3 Gastalo 500mg tablets continuously for 1 to 2 weeks. Then, take Gastalo 500mg daily with 3 times, take 1 tablet each time continuously for 4 to 5 weeks. 2.2 How to use the drug Gastalo The drug Gastalo 500mg is made in the form of a soft capsule, so you can use it orally.
Take Gastalo 500mg with warm water or cool boiled water and use Gastalo 500mg right after a meal.
2.3. In case of overdose/forgotten dose of Gastalo In case of an overdose of Gastalo 500mg: Do not exceed the dose prescribed in the prescription. When you use the drug Gastalo 500mg more will not improve symptoms. Instead, they can cause poisoning or serious adverse effects on the body. If you suspect that you or someone else may have overdosed on Gastalo 500mg, go to the emergency room at your nearest hospital or care facility. Note, when you go you should bring the box, cover, or label of the drug with you to help the treating doctor get more necessary information. Do not give your Gastalo 500mg to other people even though you know they have the same medical condition or it looks like they may have a relatively similar medical condition. This can lead to an overdose of Gastalo 500mg. In case of forgetting Gastalo 500mg: If you forget a dose, take it as soon as possible. However, if it is almost time for the missed dose, skip the missed dose and take the next dose at the scheduled time. You should note that absolutely do not take Gastalo 500mg with double the prescribed dose.
3. Gastalo side effects
You need to stop using Gastalo immediately and tell your doctor or pharmacist for advice when you have any signs of an allergic reaction that is suspected to be caused by taking the medicine such as: itching, rash or hives. redness, swelling, shortness of breath, headache, dizziness ... You may also appear to have a bowel movement, abdominal distension during bowel movements. If you experience unwanted effects, please go to the nearest medical facility for timely examination and treatment.
4. Gastalo drug interactions
Drug Interactions Gastalo 500mg may alter the drug's ability to work or increase the effects of adverse events. It is best to write a list of all the medicines you are taking every day (including prescription, nonprescription and dietary supplements) and show it to your treating doctor or pharmacist. You absolutely must not use the drug, stop or change the dose of the drug without the consent of the treating doctor.
In addition, you need to consult your doctor about taking the drug with food, alcoholic beverages such as beer, wine and tobacco. Your current medical condition may affect the use of Gastalo 500mg. Tell your doctor right away if you have any health problems.
5. Some notes when using Gastalo
Before using Gastalo you need to carefully read the instructions for use and refer to the information below.
5.1. Contraindications of the drug Gastalo The drug Gastalo 500mg is contraindicated in the following cases:
People who are hypersensitive or sensitive to any of the ingredients of the drug. People with severe kidney disease. Do not use Gastalo for people who are sensitive, allergic to the active ingredients or to any of the excipients of the drug. People with lactic acidosis, methanol intoxication, fructose-sorbitol intolerance, Fructose 1, 6-diphosphatase deficiency People with severe renal failure with serum creatinine less than 3mg/100mL. 5.2. Precautions before taking Gastalo Before using Gastalo 500mg, you should note the following: Inform your treating doctor or clinical pharmacist if you are allergic to losartan, any of its ingredients. any other medicine or any ingredient contained in the medicine. You can also ask your pharmacist for a list of ingredients. Do not use Gastalo when it has expired or there is a change in smell or color. 5.3. Precautions when using Gastalo When you must take Gastalo, you need to be carefully monitored for unusual or strong side effects. Hypersensitivity reactions may occur in susceptible individuals. Use caution when using the drug in the elderly and with impaired renal function, reduce the dose in case of renal failure. Use with caution in pregnant women because there are no safety studies on this subject. It is necessary to regularly check the concentration of Gastalo in the blood and urine in case the drug is used in high therapeutic doses. Gastalo belongs to a group of drugs prescribed by a doctor, so it is absolutely not allowed to buy outside for use. During treatment with Gastalo, you need to follow the instructions not to increase or decrease the dose to achieve maximum effectiveness and limit unwanted reactions. Ability to drive and use machines: Gastalo has no effect on the ability to drive and use machines. However, many studies have also shown that the risk of causing dizziness, so the doctor may depend on the specific case to recommend or not recommend the use of the drug when driving and operating machinery. Pregnancy: The safety of Gastalo in pregnancy has not been established. If necessary, you should consult with your doctor or pharmacist to weigh the benefits and risks of using Gastalo. Lactation: The safety of Gastalo in nursing women has not been established. If necessary, you should consult your doctor to weigh the benefits to the mother and the possible risks to the baby. Gastalo contains the main ingredient L-Ornithin L-Aspartat 500mg. This is a drug with good effects in protecting the liver, treating liver diseases, especially the drug is used in the treatment of pre-coma or hepatic coma. To ensure effective treatment and avoid side effects, patients need to take medicine according to prescription or consult a doctor or pharmacist.
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