What does Forane do?

This is an automatically translated article.

1. What is Forane?

Forane anesthetic contains the active ingredient Isoflurane, this is an anesthetic used for the following purposes:
Temporarily inhibiting the activity of the nervous system, thereby completely losing the patient's body sensation, including loss of consciousness, for surgical procedures; Put the patient into a deep sleep, no longer feeling pain; Helps maintain deep sleep with relief of pain during surgery.

2. What does Forane do?

The active ingredient Isoflurane in Forane is essentially an inhalation anesthetic, belonging to the group of halogenated anesthetics. The advantage of the drug Forane is the rapid induction and release of anesthesia in a short time.
The smell of Isoflurane has a slightly irritating, ether-like character, which may in part slow down the induction of anesthesia for Forane. This anesthetic rapidly inhibits pharyngeal and laryngeal reflexes, thus facilitating easy intubation.
Some other characteristics of Forane anesthetic:
Anesthetizes but does not stimulate increased salivation and bronchial secretions; Support to reduce spasmodic bronchial muscle tone, so Forane can be used for asthma patients; Anesthesia with Forane stimulates a slight increase in blood flow to the brain, while the metabolism of brain cells is slightly reduced compared with halothane; Increased myocardial sensitivity to the arrhythmic effects of adrenaline but still less than that of Halothan; Under general anesthesia, Forane can induce muscle relaxation suitable for certain abdominal surgeries. If deeper muscle relaxation is required, a combination of small doses of intravenous muscle relaxants should be used.

3. Indications and contraindications of Forane anesthetic

Forane is usually prescribed in the following cases:
People are suffering from serious, difficult-to-treat diseases and can only maintain life for a short time; Women preparing to have surgery to capture children for reasons that make it impossible to give birth naturally; People with insomnia, have trouble sleeping for a long time, despite using many other drugs but still not effective. Accompanied by a number of cases where Forane should not be used:
Allergy to Isoflurane or any of the ingredients in Forane; The patient had a history of malignant hyperthermia during anesthesia with isoflurane.

4. Instructions for using Forane

4.1. How to use Forane anesthetic The first thing is to shake the Forane spray well before use so that the active ingredients inside are combined more effectively. Then proceed to spray directly into the patient's nose from 1 to 2 times. In some cases, it is possible to spray Forane into the air, pillows, blankets, clothes ... or in general the surrounding space that the patient can smell easily.
If using Forane for other people, the sprayer needs to make sure to keep a safe distance from the patient from 2 to 3 meters. On the other hand, to increase the level of safety, it is best for the sprayer to hold their breath while spraying Forane or using a medical mask.
4.2. Forane anesthetic dosage Select the dose of Forane for each specific patient, and at the same time it is necessary to assess and monitor the patient's ability to secrete fluid and heart rate. When Forane is combined with oxygen, it can lead to coughing, shortness of breath or laryngospasm. However, this effect can be prevented by giving the patient an extremely short-acting barbiturate dose.
Specific Forane Dosage:
Isoflurane dose of 1.5 to 3% is recommended for anesthesia in 7 to 10 minute surgeries; Maintenance of anesthesia in surgery can use Forane concentration 1 to 2.5%, especially when used concurrently with nitrous oxide. In case of only combining Forane with oxygen, the concentration can be increased by 0.5 to 1%; If surgery requires more muscle relaxation, your doctor may use additional muscle relaxants.

5. Forane side effects

Feeling tired or vomiting after waking up; increased and irregular heartbeat (arrhythmia); Allergic or hypersensitivity reactions, skin rash or swelling of the face; Lower blood pressure after taking Forane, especially when the patient is already taking antihypertensive drugs; The levels of certain enzymes in the blood and the number of blood cells may change; agitation, delirium, mood swings, mental impairment and convulsions; Malignant high fever in some people, requiring intensive treatment because of the life-threatening risk; Mild to severe effects on liver function have occurred after Forane anesthesia with signs of jaundice and hepatitis; Increased white blood cell count; Increased blood sugar; Respiratory abnormalities or difficulty breathing due to bronchospasm; In rare cases, Forane causes hyperkalemia, leading to an increased risk of cardiac arrhythmias, even leading to death in children in the postoperative period; Use of Forane may increase the risk of underlying muscle diseases, especially Duchenne muscular atrophy.

6. Drug interactions with anesthetic Forane

Active substances that can interact with Forane:
Isoniazid (in the treatment of tuberculosis); Ephedrine decongestant; Opioids and other sedatives; Amphetamines; Calcium channel blockers ; sympathomimetic drugs such as isoprenaline; Non-selective MAO inhibitors (antidepressant treatment); Sympathomimetic beta receptor blocker.

7. Some notes when using Forane

Some conditions to note before taking Forane:
People with increased intracranial pressure; Have coronary artery disease or other cardiovascular disease; have symptoms such as jaundice, fever, enlarged liver or blood problems; Low blood pressure; Anemia or weakness; Unusual bronchospasm, cough, wheezing, or trouble breathing; Having certain conditions that affect muscle function such as neuromuscular disease (muscle dystrophy or myasthenia gravis); History of QT prolongation or torsades de pointes; The patient has a history of negative reactions after taking Forane or similar anesthetics. Notes when using Forane for pregnant women and nursing mothers:
Studies in experimental rats have demonstrated that Forane does not affect fertility, pregnancy, labor and other effects on baby mice. In addition, there is no evidence that Forane can cause birth defects. To date, there have been no safety studies of Forane in pregnant or lactating women.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.