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Prescription drug Dopegyt belongs to the group of treatment of blood pressure, cardiovascular. The use of the drug is to reduce blood pressure in patients with moderate or mild hypertension, including hypertension in pregnancy.1. What does Dopegyt do?
Dopegyt drug contains the active ingredient Methyldopa, which is prepared in the form of 250mg film-coated tablets. The drug is commonly prescribed to treat high blood pressure.
After entering the central nervous system, Methyldopa will be converted into Alpha-methyl Noradrenalin, which has the effect of reducing arterial pressure through stimulation of Alpha Adrenergic receptors, which inhibits the heart, lowering blood renin levels. analogous or pseudo-neuronal transmission. This active ingredient has also been shown to reduce tissue concentrations of Dopamine, Serotonin, Norepinephrine and Epinephrine.
Dopegyt is indicated for use in patients with mild to moderate hypertension; women with gestational hypertension to which other treatments have failed.
2. Instructions for using Dopegyt
Dopegyt dosage needs to be individualized. Here are suggestions for use for reference only:
Adults : Take 250mg, 2-3 times/day for the first 2 days. Then increase the dose or decrease the dose (evening dose) with an interval of not less than 2 days, maintaining the dose of 500-2000mg/day, divided into 2-4 times. *Note: If blood pressure is not reduced satisfactorily with the dose of 2g/day, you should consult your doctor to combine with other antihypertensive drugs;
Elderly: Do not use more than 250mg / day, if necessary, the dose can be gradually increased with an interval of not less than 2 days. Use up to 2g/day; Children: The starting dose is 10mg/kg/day, divided into 2-4 times. Gradually increase the dose at intervals of not less than 2 days (if necessary). Use up to 65 mg/kg/day to 3g/day. Dosage: Take Dopegyt before or after meals, as directed by your doctor or according to the instructions on the label.
Thuốc Dopegyt được chỉ định dùng trong các trường hợp bệnh nhân bị tăng huyết áp
3. Side effects of drugs
When taking Dopegyt to treat high blood pressure, some people may experience some non-serious side effects such as drowsiness, transient headache, weakness or weakness.
Other rare reactions include:
Feeling of severe angina; Positive Coombs test; Have Parkinson's syndrome; Stuffy nose ; Pancreatitis; Epidermal necrosis due to toxicity; Lichenoid rash or eczema; Mild joint pain, muscle pain.
4. Note before using the drug
Dopegyt should be used with caution in the following cases:
Patients with liver disease, liver dysfunction or jaundice; People with cerebrovascular disease on both sides, themselves or their families have disorders of porphyrin metabolism in the liver; People who are being monitored hematology, perform Coombs test, liver function; Person preparing for surgery; People with hemolytic anemia, fever, increased edema, appearance of cardiac symptoms or involuntary chorea - dance movements. Dopegyt is especially contraindicated in the following cases:
People with signs of sensitivity to the drug's components; Have advanced liver disease; The patient is taking an MAOI drug; Patients with depression ; Patients with pheochromocytoma. In addition, in the process of taking the drug, in order to achieve the highest therapeutic effect, the patient should avoid using alcoholic beverages; Do not drive or operate machinery while taking the drug.
Regarding the issue of “Dopegyt drugs affect the fetus”, there are not enough data to confirm. Many reports have also published the safety of the drug when used to treat hypertension in pregnant women. However, like any other drug used for pregnant women, it is still necessary to combine close medical monitoring to prevent unwanted cases from occurring.
Uống Dopegyt trước hoặc sau bữa ăn
5. Drug interactions
Dopegyt may interact with MAOIs (causing excessive hypotension). Caution should be taken when administering Dopegyt with drugs that reduce the antihypertensive effect such as: Amphetamines, CNS stimulants, iron-containing hemopoietic agents, tricyclic antidepressants, non-steroidal anti-inflammatory drugs (NSAIDs), drugs. Oral contraceptives , Phenothiazines and anesthetics...
Drugs that may alter the therapeutic effect of Dopegyt are: Lithium, Bromocriptine, Levodopa, Haloperidol, anticoagulants...
Hope the information The above information has helped readers understand the basic information about the use and use of Dopegyt antihypertensive drug. However, patients should not arbitrarily use, stop taking or change the dose without the consent of the doctor.
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