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Brudoxil 500mg is a drug used in the treatment of mild and moderate bacterial infections such as pharyngitis, tonsillitis, respiratory tract infections, urinary tract infections, ... Knowing the drug information will help the process of use. be more efficient.
1. What is Brudoxil 500mg?
Brudoxil 500mg is an antibiotic used in the treatment of mild and moderate infections such as urinary tract infections, pharyngitis, tonsillitis, respiratory infections....
In each Brudoxil 500mg tablet, in addition to the ingredients. The main ingredient is cefadroxil, brudoxil also contains excipients such as microcrystalline cellulose, pure nacl, which helps to ensure the volume, solubility, and stability of Brudoxil 500mg tablets.
2. What are the effects of Brudoxil?
With the main ingredient being cefadroxil, an antibiotic belonging to the cephalosporin group, brudoxil is used in the treatment of mild and moderate infections.
Brudoxil 500mg is specifically indicated in the following cases:
Patients with urinary tract infections Infections of the skin, skin structures. Respiratory tract infection, tonsillitis , pharyngitis. In patients with penicillin allergy: as an alternative to amoxicillin, ampicillin in the prophylaxis of endocarditis due to hemolytic streptococus infection.
3. Contraindications of Brudoxil 500mg
Brudoxil 500mg should not be used in the following patients:
Patients with a history of allergy or hypersensitivity to any ingredient of Brudoxil. The patient has a history of allergy to cephalosporin antibiotics.
4. Dosage and how to use Brudoxil 500mg
Brudoxil 500mg is used as prescribed by the doctor. You can refer to the dose as follows:
For adults and children weighing over 40kg: 1-2 tablets x2 times/day depending on the degree of infection. Or 1g x 1 time/day in case of skin, soft tissue infections and uncomplicated urinary tract infections. For children weighing 40kg or less: - Children under 1 year old: 25-50mg/kg body weight/24 hours, divided into 2-3 times.
- Children from 1-6 years old: 250mg x 2 times/day.
- Children over 6 years old: 500mg x 2 times/day.
For the elderly: Cefadroxil is excreted by the kidneys, so it is necessary to check and monitor renal function from which to adjust the dose as in patients with renal failure.
Patients with renal impairment: The initial dose of 500mg-1g can be used. Subsequent doses adjusted according to creatinine clearance are as follows:
- ClCr 25-30mL/min: adjust dose at intervals of 12 hours.
- ClCr 10-25mL/min: adjust dose every 24 hours.
- ClCr 0-10mL/min: adjust dose every 36 hours.
The course of treatment with brudoxil must be maintained for at least 5 - 10 days.
How to use Brudoxil 500mg: Brudoxil 500mg is used orally, Brudoxil is not affected by food, so you can take it when full or hungry. However, to reduce the gastrointestinal side effects of the drug, it is best to take brudoxil with food.
5. Side effects of brudoxil 500mg
Like any other medicine, Brudoxil 500mg can cause unwanted effects for users. The specific side effects of Brudoxil 500mg are as follows:
Abdominal pain, vomiting, nausea, diarrhea, pseudo-conjunctivitis. Allergic reactions, itching, urticaria, swelling, possibly anaphylaxis. Vaginitis, genital pruritus, genital thrush, testicular pain Jaundice, elevated liver enzymes, reversible increase in transaminases. Increased blood urea and creatinine, nephrotoxicity. Increased eosinophils in the blood, neutropenia, thrombocytopenia, anemia. Headache, convulsions, joint pain. Above are some side effects of Brudoxil 500mg. However, this is not the case with all patients taking Brudoxil 500mg. So if during use you encounter any unwanted effects, please stop using, immediately notify your doctor or go to the nearest medical facility for timely treatment to ensure safety for you. health.
6. What to do if you forget a dose of Brudoxil
If you forget to take a dose of Brudoxil, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose exactly as directed by your doctor. Never take a double dose of Brudoxil to make up for a missed dose.
7. Be careful when using Brudoxil 500mg
Caution should be exercised when using Brudoxil 500mg in the following specific cases:
Patients with a history of allergy to penicillin antibiotics, because studies have shown cross-complications between penicillin antibiotics and cephalosporin antibiotics. In premature babies and newborns: The use of drugs for treatment should be very cautious, using drugs only when absolutely necessary for treatment and strictly follow the doctor's instructions. Caution in patients with impaired renal function, renal failure. Careful clinical monitoring and appropriate laboratory testing should be performed in patients with renal impairment or suspected renal failure before and during treatment with Brudoxil. Long-term treatment with Brudoxil may cause superinfection by increasing the growth of non-susceptible strains. If superinfection occurs while taking the drug, discontinue use. Patient has inflammatory bowel disease, is having digestive diseases. At present, there are not enough safety data and there are no reports of harmful effects of using Brudoxil in pregnant women, so consult your doctor before taking this medicine and only use it. brudoxil when absolutely necessary for treatment. In lactating women: according to studies, the excretion of brudoxil is low, but should be considered if the child has symptoms such as diarrhea, rash.
8. Brudoxil 500mg . drug interactions
Some drugs and foods may interact when used with Brudoxil 500mg, specifically as follows:
When Brudoxil 500mg is used together with cholestyramine: cholestyramine binds to cefadroxil in the intestines, slowing down the absorption of cefadroxil. medicine. Probenecid may decrease the excretion of cephalosporin antibiotics. Co-administration of Brudoxil 500mg with diuretics such as furosemide or aminoglycoside antibiotics may synergistically increase nephrotoxicity. Store brudoxil 500mg at room temperature, in a cool, dry place, away from light and reach of children.
In summary, patients need to clearly pay attention to the information about Brudoxil in order to use it to achieve the best effect.
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