This is an automatically translated article.
The drug kremil s is quite common in family medicine cabinets. However, many people wonder what kremil-s drug treats? Accordingly, Kremil-S is indicated to treat digestive diseases such as excess stomach acid, heartburn, acid indigestion, stomach pain, bloating.
1. What is Kremil s?
The drug kremil s includes the following active ingredients: Aluminum Hydroxide, Magnesium Hydroxide and Simethicone. Specifically, each kremil s chewable tablet contains: Aluminum Hydroxide 178 mg, Magnesium Hydroxide 233 mg and Simethicone 30 mg.
These ingredients create a combination of antacids, Aluminum Hydroxide and Magnesium Hydroxide, which effectively raise the pH in the stomach by neutralizing the acid produced in the stomach. Furthermore, this product also contains Simeticone, a low surface tension water repellent used to reduce bloating in the gastrointestinal tract by causing small air bubbles to coalesce into large bubbles. more easily, allowing intestinal juices to pass more easily.
2. Indications for the use of kremil s
Kremil s is used for the following purposes:
To relieve symptoms of hypersecretion associated with peptic ulcers, gastritis, esophagitis and dyspepsia. As an anti-flatulence agent for the relief of symptoms of flatulence, including postoperative pain, associated with hypersecretion. As an adjunct to H2 blockers or proton pump inhibitors for the rapid relief of peptic ulcer symptoms.
Thuốc kremil s hiện diện khá phổ biến trong các tủ thuốc của gia đình
3. Dosage and instructions for use of the drug kremil s
Kremil s can be chewed and then swallowed without water or swallowed whole with water.
Recommended Adult Dose: 1 to 2 tablets to be taken one hour after each meal and at bedtime or as directed by a physician. If taking more than the recommended dose, consult your doctor.
In case of missed dose then just take the next dose at the recommended time or schedule. Do not double the dose unless advised by your doctor.
4. Signs of an overdose of the drug kremil s
Aluminum Hydroxide can accumulate in the bones, lungs and nervous tissues in patients with renal failure. Large doses or long-term use of the aluminum component can also cause phosphorus depletion, characterized by loss of appetite, irritability, and muscle weakness. In addition, long-term use of kremil s can cause kidney stones, osteomalacia (softening of bones) and osteoporosis.
Hypotension, nausea, vomiting, ECG changes, respiratory or mental depression, and coma have also been reported with large doses of magnesium in patients with severe renal disease.
Simeticone overdose is not expected to cause any clinically important effects. Even so, if the patient has taken more than the recommended dose, consult a physician.
Nếu sử dụng thuốc kremil s lâu dài còn có thể gây sỏi thận
5. Possible drug interactions with kremil s
Kremil s in particular and antacids in general reduce the absorption of tetracycline and iron supplements. Therefore, tetracycline should be taken 1 hour before or 2 hours after taking the antacid and 2 hours before or 3 hours after the iron preparation.
Besides, antacids can reduce the absorption of oral Digoxin or Indomethacin, Isoniazid, Quinolones (eg, Ciprofloxacin, Ofloxacin), Ketoconazole.
Antacid-induced changes in urine pH increase urinary excretion and decrease blood levels of salicylates such as Aspirin.
An increase in urinary pH due to antacids may decrease excretion of weakly basic drugs (eg, Quinidine, Chlorpromazine, Propranolol, Diazepam) and increase excretion of weakly acidic drugs (eg, Phenytoin, Pentobarbital , Warfarin).
Combination of Aluminum-Magnesium antacid has been reported to increase absorption of Dicumarol, Diazepam and Pseudoephedrine.
Antacids reduce the bioavailability of bisphosphonates (eg, Alendronate, Etidronate, Risedronate).
In summary, kremil s is indicated for the symptomatic relief of hypersecretion associated with peptic ulcer, gastritis, esophagitis and dyspepsia. Accordingly, this is an anti-flatulence drug to alleviate gastric symptoms, including postoperative abdominal pain, associated with increased secretion. Thus, knowing what drug kremil-s treats and using it properly, this will be an effective adjunct to H2 blockers or proton pump inhibitors to rapidly reduce the symptoms of peptic ulcers.
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