This is an automatically translated article.
Baloxavir belongs to the group of antiviral drugs that contain an endonuclease inhibitor of acid polymerase PA, which is active against influenza A and B. However, during the treatment, Baloxavir may cause some effects. unwanted side. Therefore, before using Baloxavir, patients need to learn carefully about the drug and follow the doctor's instructions when treating with Baloxavir.
1. Mechanism of action of the drug Baloxavir
Baloxavir drug has the main ingredient including Baloxavir marboxil - a selective endonuclease inhibitor that helps block the polymerase function and perform viral mRNA replication of the influenza virus. This compound in Baloxavir shows therapeutic activity against influenza A and B virus infections including strains resistant to current antiviral agents. Baloxavir also inhibits certain enzymes that are thought to be necessary for influenza virus replication. Therefore, administering a rapid treatment of influenza virus infection will also reduce the symptoms associated with the infection.
Baloxavir used as a single dose has been shown to be superior to placebo in reducing flu symptoms. This drug is also likely to outperform oseltamivir in virological outcomes.
Compared with oseltamivir, the compound Baloxavir marboxil is evaluated to be more favorable and more effective in treating influenza with a single dose.
2. Indications and contraindications to the use of Baloxavir
Baloxavir is indicated for the treatment of acute, uncomplicated influenza caused by influenza A and B viruses. It usually occurs in adults and adolescents over 12 years of age with symptoms for less than 48 hours, including healthy subjects as well as those at high risk for influenza-related complications.
However, Baloxavir may be contraindicated in cases of hypersensitivity to all components of the drug.
3. Dosage and how to use Baloxavir
Baloxavir is used for children in the treatment of influenza A, B:
For children with acute and uncomplicated influenza A and B virus infections using oral Baloxavir: children over 12 years old with weight If you weigh less than 80 kg, use Baloxavir as a single dose of 40 mg within 48 hours of symptom onset. As for children over 12 years old who weigh more than 80kg, use a single dose of 80mg Baloxavir within 48 hours after symptom onset. In the case of prevention of influenza A and B virus infections, oral baloxavir is also used: children over 12 years of age weighing less than 80 kg should take Baloxavir with a single dose of 40 mg within 48 hours after contact with a person with influenza. . As for children over 12 years old and weighing more than 80kg, use a single dose of 80mg Baloxavir within 48 hours after contact with a person with influenza. Baloxavir medicine is used for adults in the treatment of influenza A, B
For children with acute and uncomplicated influenza A and B virus infections using oral Baloxavir: adults weighing less than 80 kg, use Baloxavir in a single dose of 40 mg within 48 hours of symptom onset. For adults weighing more than 80 kg, a single dose of 80 mg Baloxavir should be used within 48 hours of symptom onset. In case of prevention of influenza A and B virus infections, also use Baloxavir by mouth: adults weighing less than 80 kg use Baloxavir with a single dose of 40mg within 48 hours after contact with a person with influenza. As for adults who weigh more than 80kg, use a single dose of 80mg Baloxavir within 48 hours of contact with a person with influenza.
4. Unwanted side effects when using Baloxavir
Baloxavir brand-name drug may cause some unwanted side effects during treatment such as nausea and vomiting, diarrhea, headache, bronchitis, sinusitis...
Interactions of drugs Baloxavir have may alter your ability to work or may increase the effects of side effects. Therefore, before using Baloxavir, the patient needs to inform the doctor about the list of previously used drugs, including: prescription drugs, non-prescription drugs, herbs... The doctor depends on the situation. realistic model can choose the appropriate treatment regimen while avoiding drug interactions that reduce the effectiveness of the drug Baloxavir.
Baloxavir can cause sensitive reactions including anaphylaxis, angioedema, urticaria, erythema ... so during use, if you encounter any abnormal signs, you should immediately notify your doctor. doctor for timely medical assistance.
For pregnant women, there are no adequate studies on the use of Baloxavir. However, before using this drug for this subject, it is necessary to carefully weigh the risks and benefits to avoid side effects or affect the health of both the mother and the fetus.
Hopefully, sharing about Baloxavir will help patients understand the use and use of the drug so that it is effective and minimizes unnecessary side effects.
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