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Vixcar is made in the form of film-coated tablets, with the main ingredient being Clopidogrel. The drug is used in the treatment of reducing atherosclerotic events.
1. What effects does Vixcar have?
Vixcar 75mg medicine has the main ingredient is Clopidogrel 75mg. Vixcar is indicated in the following cases:
Reduces atherosclerotic events: Stroke, myocardial infarction, cerebrovascular accident, ... in patients with atherosclerosis Presented by stroke, recent ischemia, recent myocardial infarction, or established peripheral arterial disease; Treatment of patients with acute coronary syndromes without ST-segment elevation (those with unstable angina or non-Q-wave myocardial infarction) including patients with coronary stent placement during intervention. percutaneous coronary intervention, used in combination with aspirin; Treatment of patients with acute ST-segment elevation myocardial infarction, in combination with aspirin in patients receiving medical therapy and thrombolytics. On the other hand, Vixcar is contraindicated for use in the following cases:
People who are allergic to Clopidogrel or other excipients of the drug; People with diseases that can cause bleeding: Intracerebral hemorrhage, retinal hemorrhage, ulcers in the gastrointestinal tract; Women who are breastfeeding; Patients with severe liver failure.
2. Usage and dosage of Vixcar
Vixcar 75mg is taken orally. Patients should take the tablet whole with a little water, can take it with meals or after meals. Ideally, the patient should take the medication at the same time each day.
Dosage of Vixcar is recommended as follows:
Adults from 18 years of age: Take 1 Vixcar 75mg tablet/time/day; Patients with acute coronary syndromes without QT-segment elevation (unstable angina, non-Q-wave myocardial infarction): Initial dose is 300 mg/time on the first day. After that, the patient takes 75mg for each subsequent day, combined with aspirin with a concentration of 75 - 325mg/time/day; Patients with acute myocardial infarction with ST-segment elevation: Use a dose of 75mg/time/day, in combination with aspirin; Elderly or patients with renal impairment: No dose adjustment is required. When an emergency or overdose occurs, the patient should immediately call the emergency center or go to the nearest hospital for timely treatment. If a dose of Vixcar is missed, the patient should take it as soon as possible. If it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.
3. Side effects of Vixcar
Some side effects that patients may experience when using Vixcar:
Common: Nosebleeds, easy bleeding, bruising, abdominal pain, diarrhea, loss of appetite, nausea, gastrointestinal bleeding (stomach - intestines); Uncommon: Neutropenia, thrombocytopenia, pruritus, erythema, skin bleeding (purpura), hematoma, dizziness, dysesthesia, headache, peptic ulcer, bleeding Intracranial bleeding, vomiting, flatulence, constipation, bleeding in the conjunctiva of the eye or retina, blood in the urine, etc. When experiencing any side effects of Vixcar 75mg, the patient should immediately inform the doctor. doctor for timely intervention.
4. Be careful when using Vixcar
Some notes patients need to remember before and while using Vixcar:
Be careful when using Vixcar in patients with liver or kidney failure; In patients with acute myocardial infarction, Vixcar should not be used for the first few days; Clopidogrel in Vixcar slows blood clotting, so caution should be exercised when Vixcar is used in patients at high risk of bleeding due to surgery, trauma or other medical conditions; During the use of Vixcar, the patient's bleeding time may be longer than usual. However, the patient should stop taking the drug and contact the doctor immediately if there is abnormal bleeding; The use of Vixcar in pregnant women is not recommended. Patients should only use the drug when absolutely necessary, the benefits outweigh the possible risks; Vixcar drugs can be excreted in breast milk, so breastfeeding women must not use the drug or be forced to stop breastfeeding during the time taking Vixcar; Patients taking Vixcar should tell their doctor if they need surgery (including dental surgery). Because this medication prolongs bleeding time, your doctor may ask you to stop taking it at least 5-7 days before surgery.
5. Vixcar drug interactions
Vixcar 75mg may change the effectiveness of other medicines or increase side effects. To avoid drug interactions, patients should inform their doctor about the drugs/functional foods they are taking. At the same time, patients are not allowed to arbitrarily use the drug, stop the drug or change the dose without the doctor's permission.
Some drugs that can interact with Vixcar include:
Aspirin: There may be an interaction between Clopidogrel (the main ingredient of Vixcar) and Aspirin, increasing the risk of bleeding. Therefore, patients should be cautious when combining these two drugs. However, Clopidogrel and Aspirin can be combined if treatment is prolonged up to 1 year; Heparin: An interaction between Clopidogrel and Heparin may increase the risk of bleeding. Therefore, if using these two drugs at the same time, the patient should be careful; Warfarin: Concomitant use of Clopidogrel and Warfarin may increase the risk of bleeding, so patients should also be careful; Non-steroidal anti-inflammatory drugs (NSAIDs): Research has shown that concomitant use of naproxen and clopidogrel may increase the risk of gastrointestinal bleeding. Therefore, caution should be exercised when clopidogrel is co-administered with NSAIDs; At high concentrations, Clopidogrel inhibits Cytochrome P450 (2C9), so it can interfere with drugs metabolised by the cytochrome P450 system such as tamoxifen, tolbutamide, torsemide, phenytoin, warfarin, fluvastatin and other NSAIDs. Caution should be exercised when clopidogrel is combined with these drugs; Concomitant administration of Clopidogrel with an inhibitor of CYP2C19 enzyme activity may decrease the concentration of the active metabolite Clopidogrel. Therefore, caution should be exercised when clopidogrel is co-administered with CYP2C19 inhibitors such as: omeprazole and esomeprazole, fluoxetine, moclobemide, cimetidine, carbamazepine, fluvoxamine, voriconazole, fluconazole, ticlopidine, ciprofloxacin, oxcarbazepine and chloramphenicol; Alcohol can increase the risk of stomach bleeding when using Vixcar. Therefore, patients should limit or preferably not drink alcohol while using the drug. When using Vixcar, the patient should follow all instructions of the doctor. This ensures the best treatment effect and avoids the risk of unpredictable complications.
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