Uvadex drug: Uses of the drug, indications and notes when taking the drug

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Uvadex is a drug of the drug group METHOXSALEN. This medicine is used to treat the skin problem T-cell lymphoma (CTCL), which is a type of cancer that affects the skin and blood and sometimes the lymph nodes and other organs. Drugs administered by injection.

1. What is Uvadex?

Uvadex is used to treat the skin problem T-cell lymphoma (CTCL) is a type of cancer that affects the skin and blood and sometimes the lymph nodes and other organs. It is caused by the uncontrolled growth of abnormal white blood cells in the skin. This medication is used in a procedure called photovoltaic. Part of your blood is taken out of your body through a vein and put into a special machine that separates the white blood cells. The machine adds methoxsalen to these white blood cells, and then shines ultraviolet (UV) light on them. The machine returns the treated cells (and remaining blood) to your body through the same vein.
Your immune system is supposed to respond to the treated cells and other similar untreated T cells that are not working properly. This effect helps restore your immune balance and relieve skin problems (eg rashes, plaques, tumors) of CTCL. Methoxsalen is known as a psoralen photosensitizer. It works by making the treated white blood cells more sensitive to UV light.

2. How to use Uvadex?

This medication is given by injection into the skin and collects your blood cells in photopheresis. This medication is usually taken once a day for 2 days in a row or as prescribed by your doctor. Electrophoresis is usually repeated every 4 weeks depending on your response to treatment. The dosage is based on your medical condition, the number of white blood cells collected, and your body's response to treatment.

3. Does Uvadex have any side effects?

When using Uvadex, the body may experience some unwanted effects, including:
Dizziness, headache Body weakness Leg cramps Mouth has a bitter or sour taste Freckles skin Dry skin and skin Aging can also occur Serious side effects, including: depression, swollen ankles, swollen feet, abnormal skin sores, irregular heartbeat. A very serious allergic reaction occurs while taking this medicine, get medical help right away if you notice any of the following symptoms including: generalized rash, itching, or swelling (especially facial area, tongue area, throat area), dizziness, difficulty breathing. This is an incomplete list of side effects from Uvadex. If you experience other side effects, or they persist or worsen, talk to your doctor right away to find a solution. Once your doctor directs you to use this medicine, it means that they have evaluated the benefits of the drugs more than their side effects. In many cases, the drug was used without any serious side effects.

4. Possible drug interactions when taking

Using more than one drug together can make or break the benefits of each drug. Therefore, absolutely do not arbitrarily adjust the dose, including increasing or decreasing, or combining drugs together without the consent of the doctor. Some drugs that interact with this Uvadex include:
Anthralin Bacteriostatic soap Coal tar Certain dyes (methylene blue, toluidine blue, bengal pink, methyl orange) Griseofulvin Nalidixic acid Sulfa antibiotics (e.g. sulfamethoxazole , sulfisoxazole ) Tetracycline antibiotics (eg, doxycycline, tetracycline) Water pills Thiazide diuretics such as hydrochlorothiazide

5. Some issues to note when using and storing drugs

Tell your doctor or pharmacist if you are allergic to the drug or its ingredients, to sunlight, or if you have any other allergic problems. This medicine should not be used if you have certain medical problems, so before using this medicine tell your doctor or pharmacist if you have ever had an unusual or bad reaction to the products. psoralen disease in the past, have a medical condition that makes you sensitive to light (such as lupus, certain porphyria, xeroderma pigmentosum, albinism, or no natural lens in the eye. Using this medication, tell your doctor or pharmacist your medical history, especially of: tar or UVA treatment, radiation treatment, arsenic treatment, other skin cancer (melanoma). cancer, basal cell or squamous cell cancer), cataracts, liver problems, kidney problems, heart problems In 24 hours after treatment with this medicine, eyes and skin your skin will be more sensitive to the sun, including sunlight through glass windows. Limit your exposure to the sun. To protect your skin during this time, useUse sunscreen and wear protective clothing when outdoors. To protect your eyes, wear dark sunglasses that absorb UV rays. Get medical help right away if you have vision changes, blistered skin, red, swollen, or peeling skin, or if you have a sunburn. Do not arbitrarily drive a vehicle, use or operate machinery, or do anything that requires alertness or clear vision because the drug makes you lose concentration and drowsiness, poor vision. For pregnant women and lactating women, the use of Uvadex is not recommended. Consult your doctor for the best treatment. Overdose If you take too much of this medicine and have serious symptoms such as fast heartbeat, irregular heartbeat, loss of consciousness, confusion, convulsions, fainting, or trouble breathing. Contact your doctor or medical center immediately to get medical help, avoid unnecessary risks
Missed dose If you miss a dose, take it as soon as you remember. Skip the missed dose, if it is almost time for your next dose. Do not double your dose to catch up unless your doctor tells you to.
Notes when storing Uvadex:
Do not use more medicine than prescribed by your doctor. Do not share your medication with anyone else. Store the medicine in a dry, ventilated place, avoid direct sunlight on the medicine to avoid damaging the medicine, avoid wet places to avoid affecting the quality of the medicine. Keep medicines out of the reach of children and pets to avoid them playing with or damaging dangerous medicines. With expired medicine or you want to dispose of the medicine, you need to follow the manufacturer's disposal instructions to avoid affecting the surrounding environment, especially the water environment.

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Reference source: webmd.com