This is an automatically translated article.
Zynadex is a prescription drug with anti-inflammatory effects. For more information and uses of this drug, please read our following article.
1. What is Zynadex?
Zynadex 40 medicine has the main ingredient Aescin (in the form of sodium aescinat) 40mg and excipients just enough 1 tablet. Zynadex has anti-inflammatory effects and reduces symptoms of edema caused by trauma, acute thrombophlebitis, postoperative, besides reducing permeability and increasing vascular tone.
Aescin reduces the activity of the enzyme hyaluronidase (a substance that increases blood vessel permeability).
Aescin has the ability to stimulate the secretion of hormones by the adrenal cortex, increasing the production of Prostaglandin - PGF20, releasing Norepinephrine at the end of the nerve. Thereby, increasing the pressure of smooth muscle cells in the vessel wall, leading to exhibiting anti-inflammatory effects, reducing edema.
2. Uses of the drug Zynadex
Zynadex 40 is used to treat symptoms of inflammation and edema in the following cases:
Cerebral edema due to cerebral blood vessel blockage, brain bleeding, acute encephalitis, brain surgery, traumatic brain injury, tumor brain, brain hematoma... Prophylaxis and treatment of post-operative edema symptoms, especially plastic surgery and maxillofacial surgery. Treatment of cervical, lumbar & back pain. Edema due to trauma, strong impact, dislocation, fracture, ... Venous congestion, varicose veins, lymphatic obstruction, hemorrhoids. Edema due to irradiation, burns. Vulvar & perineal edema in postpartum women.
3. Dosage and Usage of Zynadex:
Zynadex is used orally. Patients should drink with 1 glass of water, after meals.
Dosage of Zynadex drug according to the doctor's prescription. Refer to the dose as follows:
Starting dose: Take 1 tablet each time, 3 times a day. Maintenance dose: 1 tablet each time, 1-2 times a day. Dosage in case of mild symptoms: Take 1 tablet/time, use 1-2 times a day. When you miss a dose, take the missed dose as soon as you remember it. If it's almost time for your next dose, skip the missed dose and take it as scheduled. Do not take a double dose to make up for a missed dose as that can harm the body.
Overdosage of Zynadex can cause kidney failure. When using Zynadex drug overdose, it is necessary to immediately go to the nearest medical facility for a comprehensive kidney function test and assessment. Based on the results of the kidney function test, the doctor will recommend appropriate therapy.
4. Contraindications
Zynadex 40 is contraindicated in the following cases:
People who are allergic to one of the ingredients contained in the tablet. Edema due to cardiovascular disease, hemolytic disease or kidney disease. People at high risk of heart failure. Women who are taking birth control pills. Women in the first 3 months of pregnancy and during lactation.
5. Undesirable effects
During the use of Zynadex, the patient may experience symptoms of itching, hypotension, laryngeal edema... If during the use of the drug, any undesirable manifestations appear, please contact us. Immediately consult your doctor for prompt treatment.
6. Interaction of Zynadex with other drugs:
Some drug interactions with Zynadex have been recorded, including:
Birth control pills: Aescin's potency can be doubled, causing toxicity to the body when used together with oral contraceptives. Anticoagulants will increase the effect when used with Aescin do. Cephalosporin antibiotics when taken with Aescin will increase the concentration of Aescin in the blood. Zynadex when used with antibiotics of the Aminoglycoside group has the risk of increasing nephrotoxicity, so it should not be combined.
7. Notes and cautions during the use of Zynadex
Note in pregnant and lactating women:
Use Zynadex with caution in patients with renal failure with soft tissue injuries, severe burns or traumatic brain injuries. Do not use this medicine for people with rare genetic problems such as: Galactose intolerance, Lactase enzyme deficiency or Glucose-Galactose malabsorption. It is best to store the medicine at a temperature of 15-25 degrees Celsius, avoid light, it is necessary to keep it out of sight and reach of children.
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