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Zulresso is a medication that is given intravenously and under the supervision of a healthcare professional to treat postpartum depression in women. Medications are used to help relieve symptoms and reduce the risk of depression.1. What is Zulresso?
Zulresso has brexanolone as the main ingredient, which is designed for intravenous (IV) use. Brexanolone was the first FDA-approved medication to treat postpartum depression (PPD) in adult women.
Postpartum depression is a serious mood disorder that, when severe, can be life-threatening. Postpartum depression is a severe depressive episode that occurs after the birth of a baby, it is possible that symptoms also began during pregnancy. Like other forms of depression, this condition is characterized by sadness, loss of interest in activities one once enjoyed, and a decreased ability to feel joy, which can manifest with symptoms such as cognitive decline, feelings of worthlessness or guilt, or suicidal ideation.
Postpartum depression can lead to serious consequences such as:
Women may think about harming themselves or harming their baby. Postpartum depression can also interfere with the mother-child relationship. Therefore, the use of drugs to treat postpartum depression is essential to reduce the risks caused by depression. Zulresso is a prescription medication indicated for postpartum depression (PPD) in adults.
2. Uses of Zulresso
Zulresso is indicated to possibly help relieve symptoms of postpartum depression in adults over 18 years of age. Thereby, helping to reduce severe symptoms of the disease, limiting the risk of self-harm for both mother and child.This drug is not usually available for treatment, but requires registration under a special medication program because of the risks associated with taking it. You need to understand the risks and benefits of the drug before taking it.
3. How to use and dose Zulresso
3.1. How to take Zulresso is given by injection as an intravenous (IV) infusion. The medicine will be given into your vein by a qualified healthcare professional. You will receive continuous infusions over a period of 60 hours (2.5 days).
3.2. Dosage Usual Adult Dose for Depression:
Hours 0 to 4: Continuous infusion of 30 mcg/kg/hour; Hours 4 to 24: administered at a dose of 60 mcg/kg/hour by continuous intravenous infusion; Hours 24 to 52: Administer 90 mcg/kg/hour by continuous intravenous infusion; Hours 52 to 56: Dose 60 mcg/kg/hour via continuous intravenous infusion; Hours 56 to 60: administered at a dose of 30 mcg/kg/hour via continuous intravenous infusion. During infusion, vital signs should be closely monitored, the drug may cause slow breathing, temporary loss of consciousness. If you have slow breathing while taking this medicine, you may need to stop taking it and if you feel like you are going to faint, tell your healthcare provider right away.
4. Zulresso side effects
Zulresso can cause mild to serious side effects. Here are some of the main possible side effects of Zulresso:
Common Zulresso side effects may include: Sedation (drowsiness, trouble thinking clearly or not being able to drive or drive a car or drive). use of heavy machinery); dizziness like feeling like you're moving when you're not; feeling like you're about to faint; Dry mouth ; flushed skin (redness and warm feeling on the skin). Most of these side effects go away within a few days or weeks. If they appear more severe or don't go away, talk to your doctor. Serious side effects from Zulresso may occur. If serious side effects occur after leaving a healthcare facility, call 911 immediately for help. Serious side effects include the following: loss of consciousness; Suicidal thoughts and behavior... Other side effects: Allergic reactions such as skin rash, itching, flushing (heat and redness on the skin), angioedema (swelling under the skin, usually on the eyelids, lips, and feet). hands or feet); swelling of the tongue, mouth, or throat; Difficulty breathing , with severe allergic manifestations requiring immediate medical attention.
5. Some things to keep in mind when using Zulresso
To make sure it is safe to use Zulresso, tell your doctor if you have ever had an allergic reaction to a medicine or any of its ingredients or have a history of other allergies; have ever had kidney disease; or if you drink large amounts of alcohol, become addicted to alcohol... Some young people, usually under 25 years of age, may also think about suicide while taking antidepressants. Always be on the lookout for changes in mood or other symptoms so that any new or worsening symptoms can be promptly reported to your doctor. The medicine needs to be taken for a continuous period of time, more than 2 days, so you need to have a plan about who will take care of your child before taking the medicine. Brexanolone can harm an unborn baby so tell your doctor if you are pregnant or you plan to become pregnant. This medicine also may not be safe for breast-feeding while using this medicine. Ask your doctor about any risks. Above is the information you need to know about Zulresso, which is used under indications and when carefully considering the benefits and risks for postpartum women. If you have any signs of postpartum depression, seek medical attention early to avoid serious harm that can affect your life and life.
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