Uses of Vipredni 16 mg

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1. What is Vipredni 16 mg?

Vipredni 16mg drug has the main ingredient is Methylprednisolone 16mg, is prepared in the form of tablets.
Methylprednisolone is a synthetic glucocorticoid with potent effects including anti-inflammatory, immunosuppressive and anti-proliferative effects.
Methylprednisolone works to reduce inflammation by reducing the synthesis of inflammatory chemical mediators such as PG, Thromboxan,... At the same time, the drug has the effect of inhibiting white blood cells from sticking to the cell wall. Injury causes fewer white blood cells to migrate to the damaged area. Thereby reducing the symptoms of inflammatory reaction such as swelling, edema, pain, red hot. Like other forms of Glucocorticoid drugs, Vipredni 16 mg also has immunosuppressive effects, reduces cell proliferation by reducing cell protein synthesis and gene transcription.

2. Effects of Vipredni 16mg

The drug has anti-inflammatory effects and suppresses the immune system. The drug is indicated for use in the following cases:
Pain relief and inflammation in rheumatoid arthritis, rheumatism, ankylosing spondylitis. Severe allergies or poor response to antihistamines. Abnormalities in the function of the adrenal cortex cause adrenal insufficiency. Autoimmune diseases: Systemic lupus erythematosus, scleroderma... Some vasculitis diseases: temporal arteritis, nodular periarteritis. Bronchial asthma, chronic ulcerative colitis, hemolytic anemia, granulocytopenia, idiopathic thrombocytopenia... Cancer treatment such as: acute leukemia, lymphoma, breast cancer, prostate cancer paralysis. Treatment of primary nephrotic syndrome. Symptomatic treatment in respiratory inflammatory diseases such as pneumonia, bronchitis, severe covid respiratory infections with lung damage... Immunosuppression in cases of organ transplant surgery. Reduce graft rejection. Vipredni drug can also be widely indicated in many different diseases that are not mentioned above. Therefore, patients should only use it as prescribed by the doctor.

3. Usage and dosage of Vipredni 16mg

How to use: The drug is in the form of tablets, should be taken with water. The best time to take is in the morning after eating around 8 to 9 am, if taking two doses, the second dose should be taken in the afternoon. In the case of long-term, high-dose use, it is necessary to adhere to the dosing time and not to stop taking the drug without reducing the dose. In addition, in some cases, to reduce side effects, doctors can apply alternate day therapy, that is, take a single dose and take it once a day.
Dosage: Dosage varies depending on the disease and age, you can refer to the dosage below.
Adults: Starting from 4 - 48 mg/day, can be used as a single dose or in divided doses depending on the disease.
Multiple sclerosis: 160mg/day for 1 week, followed by 64mg, divided into 2 days x 1 month, then reduce or maintain dose depending on the patient. Rheumatoid arthritis: Starting dose 4-6 mg/day. Acute episode, use at a dose of 16-32 mg / day, then gradually reduce the dose quickly, do not stop suddenly. Severe rheumatic disease: Dosage is 0.8 mg/kg/day divided into small doses, then a lower dose and a single daily dose. Acute asthma attack: Use dose 32-48 mg/day, for 5 days. When recovering from an acute asthma attack, methylprednisolone is rapidly tapered, and then completely discontinued. It is possible that preventive therapy containing a corticosteroid component is individualized. Chronic ulcerative colitis: Mild disease use 80 mg enema, severe exacerbation is taken orally 8-24 mg/day. Primary nephrotic syndrome: start with a dose of 0.8 to 1.6 mg/kg for 6 weeks, then may reduce the dose for 6-8 weeks. Immune hemolytic anemia: Oral high dose 64 mg/day, for 3 days, may require treatment for at least 6-8 weeks. Sarcoid disease: 0.8 mg/kg/day helps in remission in the acute stage. The low maintenance dose is about 8 mg/day. Children:
Insufficiency of the adrenal cortex, the dose is 0.117 mg/kg divided into 3 times. Other indications 0.417 - 1.67 mg/kg divided into 3 or 4 times depending on the disease.

4. Side effects of Vipredni 16mg

As with other glucocorticoids, the occurrence of side effects is largely dose and duration dependent. Some possible side effects include:
Common side effects: Abdominal pain above the navel, nosebleeds, hirsutism, increased blood sugar, joint pain, indigestion, trouble sleeping, easy provoked by external factors, cataracts, glaucoma. Uncommon side effects include: Vomiting and nausea, skin atrophy, hyperpigmentation, acne, dizziness, headache, hallucinations, confusion, psychosis, abdominal distention, stomach ulcers. Other possible side effects when using Vipredni: Cushing's syndrome is common with prolonged use, hyperglycemia, infertility, increased blood pressure, anaphylactic shock reactions, muscle weakness, osteoporosis. Inform your doctor immediately if you experience long-term or serious side effects when taking the drug for guidance on reasonable and timely management, especially hypersensitivity reactions.

5. Note when using Vipredni 16mg

The correct use of drugs will bring high treatment effectiveness and vice versa, if used incorrectly, can cause disadvantages. Here are some notes when taking the drug:
The drug is not used for people with a history of hypersensitivity to any ingredient of the drug, pregnant and lactating women, severe systemic infections, taking attenuated live vaccines. Side effects from drugs containing corticosteroids may be increased in patients with hypothyroidism or cirrhosis. It is necessary to monitor or change the dose when using. It should be used with caution in patients with osteoporosis, those with recent vascular anastomosis, those with psychiatric disorders, gastric ulcer and duodenal ulcer. Because taking drugs can increase the severity of the above disease. Acute adrenal insufficiency can occur when you take the drug for a long time but suddenly stop taking it. Therefore, when taking the drug, it is necessary to strictly comply with the doctor's request to stop taking the drug, avoid arbitrarily stopping the drug. It should be used at the lowest effective dose and for the shortest possible time in children and the elderly. Avoid vaccinations while taking medications, especially live attenuated vaccines, as they put you at risk for post-vaccination illness. Drug interactions can occur when concomitant use of drugs such as anti-inflammatory drugs, analgesics, sympathomimetic drugs, antacids ... these drugs can increase side effects or reduce the main effects of Vipredni. 16 mg. Drugs that can increase blood sugar should be cautious in people with diabetes and may need to adjust the dose of antidiabetic drugs. Vipredni 16mg is a prescription medicine, used in many different cases. However, the use of the drug also has many possible disadvantages, so the patient must absolutely adhere to the drug use and avoid arbitrarily stopping the drug.
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