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Vastrim is classified as a cardiovascular drug, used to prevent angina in heart patients, treat tinnitus and dizziness. Let's find out other uses and note how to use Vastrim through the article below.1. What is Vastrim?
Vastrim is classified as a cardiovascular drug, used in the treatment of angina attacks, adjunctive treatment for symptoms of dizziness and tinnitus. Vastrim's main ingredient is Trimetazidine, which is 20mg in each film-coated tablet and 35mg in the delayed-release tablet form. With each box of Vastrim, there will be 10 blisters of 10 pills each.
2. What are the uses of Vastrim?
The main ingredient Vastrim is Trimetazidine, an active ingredient classified as an anti-anginal and ischemic drug. With the active ingredient trimetazidine, studies in patients with angina pectoris have shown that this active ingredient helps to increase the response to coronary exercise on the 15th day of treatment. Vastrim helps to reduce changes in blood pressure with exercise, but not much change in heart rate. Vastrim is effective in significantly reducing the frequency of angina attacks and thus reducing the patient's need for Trinitrin.With the above uses, Trimetazidin is mainly indicated in the prevention of angina in patients who often encounter this condition (people with cardiovascular disease).
In addition, the application of Trimetazidin is also used in other specialties such as ear - nose - throat. The main use of this active ingredient is as an adjunct to the treatment of vertigo in ménière's disease and vascular vertigo. Clinically, trimetazidine is said to improve the vestibular status of patients.
Trimetazidin also shows an improvement in electroretinogram (ERG), increased function of the retina
Regarding pharmacokinetics, the drug Vastrim is well absorbed from the gastrointestinal tract. Plasma snow concentration peaks in plasma 2 hours after dosing. With an oral dose of 20 mg, the mean plasma concentration measured after 2 hours was 55 ng/ml. However, the protein binding rate of the drug is quite low when the in vitro measured value is only 16%. Regarding the elimination time, the elimination half-life of Vastrim is 6 hours, the main route of elimination is in the urine in the form of unmetabolized form.
3. Indications for the use of Vastrim
The main indication of Vastrim is the prophylaxis in cases of angina in ischemic heart disease.
In clinical practice and in some other specialties, Vastrim can also be indicated in the following cases:
Support in the treatment of symptoms of dizziness and tinnitus (specialist in otolaryngology). Support in the treatment of visual impairment and visual disturbances in cases of circulatory origin.
4. Contraindications to the use of Vastrim
In some of the following cases, the patient will be contraindicated to use Vastrim:
The patient has a history of allergy to Trimetazidine or any of the ingredients listed in the Vastrim leaflet. Contraindicated for use in women during lactation.
5. Dosage and how to use Vastrim
Vastrim is taken orally, so patients should take it with 1 glass of water.
Dosage of Vastrim:
20mg Vastrim tablets: Take 1 tablet/time, 3 times a day with meals. MR 35mg delayed-release tablet: Take 1 tablet/time in the morning and evening, take the drug with meals.
6. Side effects of Vastrim
In general, because it is a group of drugs used for people with cardiovascular disease, side effects of Vastrim are very rare, even rare. Side effects from clinical cases with Vastrim may be
Rare: Nausea, vomiting. Very rare: Tremor, spasticity, difficulty in movement. However, the unwanted effects of Vastrim will disappear on their own when the patient stops taking the drug.
7. Notes when using Vastrim Do not use Vastrim for patients with chest pain or for the initial treatment of unstable angina. Vastrim is not used to treat myocardial infarction. During pregnancy and lactation, the mother should not use this medicine. Vastrim is a prophylactic treatment for angina attacks, commonly used in patients with a history of cardiovascular disease. Vastrim is a prescription drug, and patients use it according to the doctor's prescription and prescription to ensure safety. The basic information about Vastrim in the above article is for reference only. Because Vastrim is a prescription drug, patients should not use it on their own, but need to contact a doctor or a qualified person directly to get a suitable prescription to ensure safety for health.
