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Usapril 20 is a prescription drug used in the treatment of a number of cardiovascular diseases such as hypertension, congestive heart failure,... So what is the use of Usapril 20 and how to use the drug? How is this?
1. Uses of Usapril 20
Usapril 20 is a cardiovascular drug, the drug is made in the form of tablets with the main ingredient in each tablet is 20mg of Enalapril maleate. Enalapril acts on the renin-angiotensin-aldosterone system through inhibition of ACE. Enalapril is effective in reducing peripheral arterial resistance. In heart failure, Enalapril maleate helps to reduce preload and afterload, cardiac output may increase but does not have a significant effect on heart rate.
Long-term treatment with enalapril reduces hypertrophy, symptoms and severity of heart failure, and increases exercise tolerance.
2. Indications and contraindications for the use of Usapril 20
2.1. Indications Usapril 20 is indicated in the following cases:
Essential hypertension Hypertension due to kidney disease. Hypertension with diabetes. The degree of heart failure, Usapril 20 helps improve survival, slow down the progression of heart failure, reduce the number of heart attacks. Treatment and prevention of congestive heart failure. Prevention of ventricular dilatation after myocardial infarction. 2.2. Contraindications Usapril 20 is contraindicated in the following cases:
People who are sensitive to enalapril. Aortic valve stenosis. Bilateral renal artery stenosis, or unilateral renal artery stenosis in a person with only one kidney. Pre-existing hypotension. Angioedema at the start of treatment with ACE inhibitors.
3. Notes when using Usapril 20
Note when using Usapril 20 in the following cases:
People with impaired kidney function. Patients with rare hereditary problems of galactose intolerance, or Lapp lactase deficiency or glucose-galactose malabsorption should not use Usapril 20. Pregnant women should not use Usapril 20, because of possible risks. cause morbidity and mortality in fetuses and infants. Enalapril in Usapril 20 is excreted in breast milk. At usual therapeutic doses, Usapril 20 has a very low risk of adverse effects in a nursing infant. People who are driving or operating machinery should be careful when using Usapril 20, because the drug can cause dizziness or fatigue.
4. Dosage and how to use Usapril 20
Usapril 20 is used orally. Patients can take Usapril 20 before or after meals, because the drug is not affected by food.
Dosage of Usapril 20 should be according to the doctor's prescription, the reference dose in specific cases is as follows:
Primary hypertension: Use a dose of 20-40mg/day, can be taken once or twice a day. divided drink 2 times a day. Congestive heart failure: Use a dose of 20mg / day, usually divided into 2 times a day. The maximum dose is 40mg / day, divided into 2 times. Asymptomatic left ventricular dysfunction: Use a dose of 20mg / day divided into 2 times a day. For patients with renal failure: Clcr from 30 - 80ml/min can be used at a dose of 20mg/day, up to a maximum of 40mg/day. Clcr < 30ml/min is not suitable to use Usapril 20.
5. Side effects of Usapril 20
During the use of Usapril 20, you may encounter some side effects of the drug. Common side effects of Usapril 20 include:
Headache Dizziness Fatigue Insomnia Paresthesias Taste disorders Diarrhea Nausea, vomiting. Abdominal pain Angioedema Lower blood pressure orthostatic hypotension Syncope Palpitations Chest pain Rash Dry cough Renal failure Uncommon side effects of Usapril 20 include:
Decrease in hemoglobin and hematocrit Agranulocytopenia proteinuria panic agitation Severe depression Rare side effects of Usapril 20 include:
Intestinal obstruction Pancreatitis Toxic hepatitis Cholestasis Oral mucosal sensitization Other Usapril 20 side effects include:
Hypersensitivity Depression Blurred vision Muscle pain Bronchospasm Asthma If you experience any side effects of Usapril 20, tell your doctor right away or go to a medical facility for timely assistance.
Interactions of Usapril 20 with other drugs
Concomitant use of Usapril 20 with certain other vasodilators or anesthetics may cause severe hypotension. Therefore, it is necessary to monitor the patient so that it can be treated promptly by increasing the volume of circulation (infusion). Concomitant use of Usapril 20 with diuretics may cause excessive hypotension after initiation of Usapril 20 therapy. In this case, the diuretic should be discontinued, or the patient increased salt intake. prior to initiation of Usapril 20. Concomitant use of Usapril 20 with drugs that induce renin release will increase the antihypertensive effect of Usapril 20. Concomitant use of Usapril 20 with other medicinal products. Hyperkalemic agents such as potassium-sparing diuretics, potassium supplements or salts containing potassium may increase serum potassium, especially in patients with renal impairment. Therefore, it is necessary to monitor the patient, and regularly check the amount of potassium in the blood. Concomitant use of Usapril 20 with lithium may cause an increase in blood lithium levels leading to lithium toxicity. Concomitant use of Usapril 20 with non-steroidal anti-inflammatory drugs, sympathomimetic bronchodilators may increase the antihypertensive effect of the drug. Concomitant use of Usapril 20 with oral contraceptives may increase the risk of vascular damage and difficulty controlling blood pressure. Usapril 20 is a prescription drug used in the treatment of a number of cardiovascular diseases such as hypertension, congestive heart failure,... To ensure effective treatment and avoid unwanted side effects Patients should strictly follow the instructions of the doctor, professional pharmacist.
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