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Trexatil is a drug used in the treatment of lower respiratory tract infections such as pneumonia, acute and chronic bronchitis. So what is Trexatil? What are the uses of Trexatil? What is the correct way to drink? What are the points to pay attention to when using? The following article will help you better understand the uses of Trexatil.1. What are the uses of Trexatil?
1.1. What is Trexatil? Trexatil belongs to the group of antiparasitic, antiviral, antifungal, anti-infective drugs, with registration number VN-14024-11, manufactured by Bharat Parenterals., Ltd - India and registered by Colorama Pharm Company. ., Ltd– Vietnam.
Trexatil has the main ingredients: Active ingredient Cefuroxim Axetil 500mg and excipients just enough in 1 tablet.
Trexatil is made in the form of 200mg film-coated tablets.
Trexatil is recommended for use in adults and children 2 years of age and older, but under the supervision of a doctor.
1.2. What are the uses of Trexatil? Trexatil is prescribed by doctors in the following cases:
Lower respiratory tract infections such as pneumonia, acute and chronic bronchitis. Upper respiratory tract infections such as ear, nose and throat infections such as otitis media, sinusitis, tonsillitis and pharyngitis. Genitourinary infections such as pyelonephritis, cystitis, urethritis. Skin and soft tissue infections such as boils, pustules, impetigo. Gonorrhea, such as acute uncomplicated gonococcal urethritis and cervicitis.
2. Usage of Trexatil blood pressure medicine
2.1. How to take Trexatil It is necessary to apply the exact dose of Trexatil indicated on the package, the drug leaflet or the instructions of the doctor or pharmacist. Do not arbitrarily calculate, apply or change the dose. Swallow the tablet whole or break it in half but do not crush it or mix it with other ingredients when taking it. 2.2. Dosage of the drug Trexatil Adults:
In bronchitis and pneumonia 500mg x 2 times/day. In most infections: 250mg twice daily. In urinary tract infections, the dose is 125mg twice daily. Uncomplicated gonorrhea: 1g single dose Children:
The usual dose is 125mg x 2 times/day or 10mg/kg x 2 times/day. Maximum dose 250mg/day. Children over 2 years old with otitis media: 250mg x 2 times/day, maximum 500mg/day. Treatment when missed dose:
Usually drugs can be taken within 1-2 hours compared to prescribed in the prescription. Unless there is a strict rule about the time of use, the medicine can be taken a few hours after forgetting. However, if the time is too far from the time you need to drink, you should not take it, which can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before making a decision.
Treatment of overdose:
Most drugs cause only nausea, vomiting, and diarrhea. However, may cause neuromuscular hyperexcitability and convulsions, especially in patients with renal failure.
Overdose management:
Attention should be paid to the possibility of multiple drug overdoses, drug interactions and unusual pharmacokinetics in the patient.
Protect the patient's respiratory tract, support ventilation and infusion. If convulsions develop, immediately discontinue use of the drug; Anticonvulsant therapy may be used if clinically indicated. Hemodialysis can remove drugs from the blood, but much of the treatment is directed toward supportive or symptomatic treatment.
3. Contraindications of Trexatil
Patients who are allergic to the active ingredient Cefuroxime or any of the excipients of Trexatil. Patients with a history of allergy to cephalosporins
4. Notes when using Trexatil
The usual course of treatment for Trexatil is 7 days.
Film-coated tablets and oral suspension are not biologically equivalent, so they cannot be used interchangeably according to the mg/mg relationship.
In general, cephalosporin antibiotics can be safely used in patients with hypersensitivity to the penicillin group, although there have been some reports of cross-reactivity. Therefore, special care should be taken when administering Trexatil to patients who have experienced anaphylaxis to penicillins. Trexatil, like other antibiotics, can lead to the proliferation of non-susceptible organisms (Enterococci, Candida, Clostridium difficile), in which cases may require discontinuation of the drug. When taking broad-spectrum antibiotics, many patients developed pseudomembranous colitis; Therefore, physicians need to consider when diagnosing the disease in patients with severe diarrhea during or after long-term antibiotic use. Glucose oxidase or hexokinase methods are recommended for the determination of blood or plasma glucose concentrations in patients receiving cefuroxime axetil. This antibiotic does not affect the alkaline picrate test for creatinine. Pregnancy and breast-feeding: There is no experimental evidence that cefuroxime axetil is teratogenic. However, as with all drugs, care should be taken during the first months of pregnancy. Cefuroxime is excreted in human milk and therefore caution should be exercised when cefuroxime axetil is administered to a nursing mother.
When Trexatil is used together with the following drugs, there will be an increase or decrease in the effect of the drug:
Decreased effect: ranitidine and sodium bicarbonate reduce the bioavailability of cefuroxime axetil. Cefuroxime axetil should be administered at least 2 hours after antacids or H2 blockers, as these may increase gastric pH. Increased effect: High-dose probenecid reduces renal clearance of cefuroxime, resulting in higher and more prolonged plasma concentrations of cefuroxime. Increased toxicity: aminoglycosides increase the potential for nephrotoxicity.
5. Side effects of the drug Trexatil
In general, the adverse effects caused by cefuroxime axetil are usually mild and last only a short time. A small number of patients taking cefuroxime axetil have experienced gastrointestinal disturbances, including diarrhea, nausea, and vomiting. As with broad-spectrum antibiotics, there have been a few (very rare) reports of pseudomembranous colitis. Headache has also been reported.
6. How to store Trexatil
Store below 25 degrees Celsius. When stored at temperatures lower than 30 degrees Celsius for up to two months, there is no harmful effect on the medicine. Keep out of reach of children
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