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Tranecid 250 belongs to the group of drugs that affect blood clotting with the main ingredient being tranexamic acid. It is commonly used to treat and prevent bleeding associated with increased fibrinolysis.1. What are the effects of Tranecid 250?
Tranecid 250 drug has the main ingredient tranexamic acid, which inhibits the fibrinolytic system, by inhibiting the activation of plasminogen to plasmin, from which plasmin is not produced. The mechanism of action of tranexamic acid is to bind strongly to the lysine binding site, the fibrin-affinity site of plasmin, and plasminogen to fibrin.
In cases of normal bleeding, the presence of tranexamic acid induces hemostasis by eliminating that fibrinolysis. In addition, tranexamic acid also has anti-allergic and anti-inflammatory effects with the ability to inhibit the production of kinins and other active peptides... by plasmin. Tranecid 250 is usually indicated in the prevention and treatment of bleeding associated with systemic or local fibrinolysis in adults and children older than 1 year:
Menorrhagia or uterine bleeding Stomach bleeding stomach, intestines Urinary tract bleeding, prostate surgery or urinary tract injury procedures Ear, nose and throat surgery (tonsillectomy, tooth extraction) Gynecological surgery or gynecological pathology Thoracic, abdominal and Serious surgical interventions such as cardiovascular surgery Control of bleeding associated with fibrinolytics Contraindications to Tranecid 250 include:
Patients with known hypersensitivity to tranexamic acid or any of the components of the drug. Acute venous or intravenous fibrinolysis after coagulopathy, except in patients with strong activation of the fibrinolytic system during acute major bleeding Severe renal impairment due to accumulation History of seizures Intramedullary injection, injection intracardiac, intracranial injection (risk of cerebral edema and convulsions)
Use of oral contraceptives ormone Acute embolism (deep embolism, pulmonary embolism, cerebral embolism) History of embolism
2. Dosage of Tranecid 250
Depending on the subjects and treatment goals, the dosage of Tranecid 250 will be different, specifically as follows:
Adults take a dose of 250-4000mg/day, divided 3-4 times The dose for Tranecid 250mg tablets : take 2 tablets/time, 2-3 times/day Blood in urine: 4 tablets/time, 2-3 times/day until no more blood in urine Severe nosebleed: 4 tablets/time, 3 times/day for 4-10 days Menorrhagia: 4 tablets/time, 2-3 times/day for 3-4 days Cervical partectomy: 4 tablets/time, 3 times/day for 12-14 days after surgery
3. Side effects of Tranecid 250
In some patients when using Tranecid 250 may experience side effects such as:
Digestive disorders: nausea, vomiting, diarrhea Dizziness Visual disturbances: change in color perception
4. Be careful when using Tranecid 250
Some general notes when using Tranecid 250 include:
Patients with kidney failure using Tranecid 250 are at risk of accumulating tranexamic acid. Patients with upper urinary tract bleeding, at risk of renal occlusion, Bleeding from disseminated intravascular coagulation, unless the disease is primarily due to a disorder of the fibrinolysis mechanism Persons with a history of thrombosis should not take tranexamic acid unless are also being treated with anticoagulants. Tranexamic acid should not be used during the first months of pregnancy, as teratogenic effects have been reported. Tranexamic acid is secreted into breast milk, but the risk of adverse effects in the infant is unlikely at normal doses, so tranexamic acid can be used when needed in nursing mothers. Concomitant use of tranexamic acid with estrogen is not recommended because it may cause more thrombosis. Caution when simultaneously using tranexamic acid with other hemostatic drugs The above are the uses of Tranecid 250, patients should refer to it to help the process of use achieve better results. If you have any further questions, you can directly discuss with a specialist doctor for appropriate indications.
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