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Torvalipin is indicated in combination with a diet to help lower blood cholesterol levels, treat primary dyslipidemia type III... Let's learn about the uses, the notes when using Torvalipin through article below.
1. What is Torvalipin?
Torvalipin contains the active ingredient Atorvastatin 20mg, which is prepared in the form of film-coated tablets. Atorvastatin belongs to the group of cholesterol-lowering drugs that act by reducing the synthesis of liver cholesterol through inhibition of the cholesterol-producing enzyme HMG - CoA reductase, thereby reducing the concentration of LDL - cholesterol and cholesterol in general, reducing the risk of atherosclerosis coronary artery disease and coronary artery disease.
Torvalipin is indicated in the following cases:
Treatment of primary hypercholesterolemia to reduce total cholesterol, Apolipoprotein B, LDL - cholesterol, triglycerides and increase HDL - cholesterol levels; Treatment of beta-lipoproteinemia in patients who do not respond adequately to diet; Reducing total blood cholesterol, LDL - cholesterol in patients with homozygous familial hypercholesterolemia when diet is inadequate.
2. Dosage of Torvalipin
Torvalipin dosage is prescribed by the doctor based on the patient's condition. The drug can be taken with or without food (bioavailability is not affected by food). Some recommendations on the dosage of Torvalipin are as follows:
Treatment of dyslipidemia and hypercholesterolemia with familial and non-familial heterozygosity: The recommended starting dose is 10-20mg/time/ day. Patients who need to reduce LDL - cholesterol much (over 45%) should start with a dose of 40mg / time / day, the therapeutic range of Torvalipin is 10 - 80mg / time / day; After treatment and/or after increasing the dose of Atorvastatin, it is necessary to assess blood lipids in 2-4 weeks and adjust the dose accordingly; Treatment of homozygous familial hypercholesterolemia: The recommended dose is 10 to 80 mg/day. Atorvastatin should be combined with other lipid-lowering treatments.
3. Torvalipin side effects
Torvalipin can cause some side effects as follows:
On the nervous system: Confusion, memory loss, headache; On the digestive system: Vomiting, nausea, diarrhea. Patients need to inform their doctor about the undesirable effects encountered while being treated with Torvalipin.
4. Notes when using Torvalipin
4.1. Torvalipin is contraindicated in the following cases:
Patients with hypersensitivity to Atorvastatin or any of its ingredients; People with advanced liver disease with unexplained persistent elevation of liver enzymes; 4.2. Precautions when using Torvalipin Before starting treatment with Torvalipin, the patient should be excluded the causes of secondary dyslipidemia and the lipid index should be quantified, the test should be performed periodically at intervals. 4 weeks. During treatment with Torvalipin, if there is an increase in creatinine kinase, myositis or a 3-fold increase in serum liver enzymes, it is necessary to reduce the dose or discontinue the drug. Caution should be exercised when using Torvalipin in patients with alcoholism and liver dysfunction. Patients should have a suitable diet before and during drug treatment. Pregnant women, lactating women: Torvalipin is not recommended in these subjects.
5. Drug interactions
Torvalipin drug may cause some of the following drug interactions:
Concurrent use of Torvalipin and anticoagulants, Indandione will increase bleeding time or prolong prothrombin time. Patients should be closely monitored in case of using the above drug combination; Erythromycin, Cyclosporine, Gemfibrozil, Niacin, immunosuppressants: Concomitant use with Torvalipin increases the risk of myopathy; Digoxin: Co-administration with Atorvastatin resulted in a slight increase in serum digoxin concentrations. Drug interactions occur that increase the risk of having an effect and reduce the therapeutic effect of Torvalipin, so to ensure safety and effectiveness in treating patients, it is necessary to inform the doctor about the drugs and foods that are being used. used before taking Torvalipin.
