This is an automatically translated article.
G5 Duratrix is a prescription drug, not self-administered, made in the form of 75mg tablets with the main active ingredient being Clopidogrel. The drug helps to reduce the risk of cardiovascular and brain diseases, limit the risk of stroke and stroke in people with atherosclerosis.
1. What are the effects of G5 Duratrix?
In each G5 Duratrix tablet contains: 75mg Clopidogrel and other excipients (Crospovidone, Microcrystalline Cellulose, Hydroxypropyl methyl cellulose, Titanium dioxide, Magnesium stearate, Nipagin...).
Some of the effects of G5 Duratrix 75mg can include:
Reduce the risk of cardiovascular or arterial - brain diseases (stroke, myocardial infarction, cerebrovascular accident ...) atherosclerotic nuclei; In combination with Aspirin (Acetylsalicylic acid) for the treatment of patients with acute coronary syndromes without ST-segment elevation (unstable angina or non-Q-wave myocardial infarction), including patients with were already on healthy treatment or had a subcutaneous coronary interventional stent placed.
2. Dosage of the drug G5 Duratrix
To promote the effect of the drug G5 Duratrix 75mg, patients should take the drug 1 time / day orally (before or after meals). When taking, should swallow the tablet whole with water, avoid breaking or crushing the drug because it is easy to reduce the effect.
In addition, the dose can also be distributed depending on the treatment purpose and age, specifically:
Prevention of the risk of myocardial infarction, cerebrovascular accident and stroke: take 1 tablet 75mg/day ; Treatment of acute coronary syndromes without ST-segment elevation (non-Q-wave myocardial infarction, unstable angina): start with an initial dose of 300 mg. The next dose is 1 tablet 75mg/day, combined with Aspirin (the first dose is 75-325mg, the next dose is 75-162mg/day); Note:
For patients over 75 years old who do not need a loading dose, just maintain a dose of 75mg in combination with Aspirin; Do not give G5 Duratrix medicine to children.
3. Side effects of G5 Duratrix
Although not all patients experience side effects, G5 Duratrix can cause some side effects such as:
Bleeding easier than usual: Nosebleeds, gastrointestinal bleeding , intracranial hemorrhage, purpura, easy bruising or bruising, hematoma; Digestive disorders: Abdominal pain, diarrhea, loss of appetite, indigestion or heartburn, gastritis, constipation...; Headache, dizziness, easy fatigue, nausea. In rare cases, serious side effects may occur, users should monitor their body's reaction and notify their doctor if they see one of the following signs:
Cough or vomiting blood; Blood in stools and urine; Abnormal bleeding; Unexplained bruising or bleeding under the skin; Jaundice, yellow eyes; Heart palpitations , difficulty breathing ; swelling of the face, throat, lips, tongue, hands, feet, or ankles; Hoarseness, sore throat, difficulty speaking, difficulty swallowing; Fever, convulsions. This is not a complete list of the possible side effects of G5 Duratrix. If you have any questions about taking the medicine, consult your doctor or pharmacist.
4. Notes when using G5 Duratrix
Before using G5 Duratrix for patients with atherosclerosis, there are some important notes to note:
G5 Duratrix should not be used for a long time because it may cause bleeding; Use with caution in patients prone to bleeding due to surgery, trauma, ulcers or other medical conditions (especially intraocular or gastrointestinal problems); People at risk of bleeding or hematologic disorders should have their blood cell counts and related tests done. Before surgery or coronary artery bypass grafting, patients need to stop using G5 Duratrix for 5-7 days; Be especially careful when using G5 Duratrix in patients with severe liver and kidney disease, pregnant and lactating women; G5 Duratrix is contraindicated in people who: are hypersensitive to Clopidogrel or any of its ingredients; patients with diseases related to bleeding (intracerebral hemorrhage, peptic ulcer, platelet disorder...); severe liver failure.
5. Drug interactions
Some interactions between G5 Duratrix with other drugs can reduce the effectiveness of treatment, for example:
Co-administration with drugs that inhibit Enzyme activity reduces drug concentrations, leading to reduced effects treatment; Concurrent use of aspirin may increase the risk of bleeding. But using both in low, controlled concentrations is beneficial; Combination with Naproxen or non-steroidal anti-inflammatory drugs (NSAIDs) may cause gastrointestinal bleeding; Taking Warfarin may increase the risk of bleeding; Do not use G5 Duratrix together with Phenytoin and Tolbutamide drugs because it may cause an increase in blood plasma levels. Omeprazole and Esomeprazole should not be used concurrently with G5 Duratrix. Above is the information you need to know about the drug G5 Duratrix. Hopefully, before using this drug, you have understood the uses and methods of use to ensure safety and maximize the effectiveness of the drug.