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Theratussine is indicated for the treatment of skin allergies with manifestations of urticaria, rash, skin swelling, redness, allergic rhinitis. The following article guides the use of Theratussine and the notes when using Theratussine.
1. What is Theratussine?
Manufacturer: TV Pharmaceutical Joint Stock Company. Pharm.
Packing: Box of 10 blisters x 25 tablets.
Dosage form: Film coated tablets.
Ingredients:
Each film-coated tablet contains:
Alimemazin Tartrat 5mg. Excipients 1 capsule.
2. Uses of Theratussine
The effect of Alimemazine in the formula
Competes with Histamine at the H1 receptor, so it works against symptoms such as urticaria, allergies, itching,... The peripheral anticholinergic effect is weak, a Some people taking the drug have symptoms such as: blurred vision, dry mouth, constipation, urinary retention. Inhibiting the enzyme Histamine N - Methyltransferase, blocking histamine secreting receptors and acting on some other receptors, so it has a sedative effect. basis for use as a pre-anesthetic. In addition, Alimemazine also has antiemetic effects, strong Serotonin resistance. 2.1 Indications The drug is used in the following cases:
Acute delirium in people with alcohol withdrawal. Respiratory and skin allergies such as: rhinitis, sneezing, urticaria. Insomnia in children and adults. Vomiting frequently in children. 2.2 How to use - Dosage of Theratussine How to use:
Take orally. Take the tablets whole, do not crush or chew the tablets. Use the drug according to the doctor's instructions, do not abuse because it can cause unwanted reactions. Dosage:
Depending on different treatment purposes, there will be different dosages:
Cure urticaria, rashes:
+ Adults: Take 10mg/time. Use 2-3 times a day. The dose can be up to 100mg / day if the patient is persistent itching, discomfort.
+ Elderly people: Reduce oral dose by 10ml/time. Use 1-2 times a day.
+ Children over 2 years old: Take 2.5 - 5mg/time. Use 3-4 times a day.
Antihistamine and antitussive effects:
+ Adults: Take 5mg - 40mg per day, divided into several times a day to use.
+ Children over 2 years old: Take 0.5 - 1mg/kg/day. Divide several times a day to use.
Sleep-inducing effects:
+ Adults: Use 5 - 20mg before going to bed.
+ Children older than 2 years: Use 0.25 - 0.5mg/kg/day. Drink before going to sleep.
2.3 How to handle missed dose, overdose Missed dose: Take as soon as you remember, if it is almost time for the next dose, skip the missed dose. Do not take a double dose to make up for the previous dose.
Overdose:
Symptoms: Drowsiness, loss of consciousness, increased heart rate, ventricular arrhythmias, hypothermia. In addition, severe extrapyramidal reactions may occur.
Treatment:
+ Early detection (After taking an overdose less than 6 hours): Take the patient to gastric lavage.
+ Use activated charcoal, if necessary, can support treatment of systemic vasodilatation.
+ In severe cases at risk of cardiovascular collapse: Intravenous infusion increases the circulating volume, the infusion must be warmed before injection.
+ If it cannot be resolved by intravenous fluids, inotropic agents such as Dopamine can be used, avoiding the use of peripheral vasoconstrictors.
+ Ventricular arrhythmias: Return to normal when body temperature, circulatory and metabolic disorders are corrected. If there is no improvement or life-threatening, antiarrhythmic drugs can be used.
+ Severe central nervous system depression: Use respiratory support.
+ Malignant syndrome due to sedatives: Keep the patient's eyes, in addition, Dantrolen Sodium can be used.
3. Theratussine side effects
Some side effects encountered when using Theratussine:
Common: Headache, dizziness, fatigue, dry mouth, thick sputum.
Uncommon: Constipation, urinary retention, eye accommodation disorder.
Rare: Agranulocytosis, agranulocytosis, increased heart rate, decreased blood pressure, hepatitis, extrapyramidal symptoms, risk of respiratory arrest,...
If during use, any abnormalities appear Any adverse effects should be reported to a qualified doctor or pharmacist for appropriate assistance.
4. Contraindications
Do not use the drug in the following cases:
People with liver and kidney dysfunction, Parkinson's disease, myasthenia gravis, hypothyroidism. Hypersensitivity to any of the ingredients of the drug. People with a history of narrow angle glaucoma. Overdose Barbituric, Alcohol, Opiat. Children under 2 years old. People with leukopenia or agranulocytosis. People with epilepsy, pheochromocytoma, prostate enlargement.
5. Notes when using the drug Theratussine
Use on pregnant women and nursing mothers
Pregnant women : The drug can cause jaundice and extrapyramidal reactions in young children. Therefore, use should be avoided by pregnant women. When necessary, consult a doctor before use.
Lactating mothers : The drug may be excreted in breast milk. Therefore, the drug should not be used on this subject. If yes, during the time of using the drug, the mother must stop breastfeeding.
People who drive and operate machines:
The drug causes dizziness, affecting the ability to drive and use machines. Therefore, caution should be exercised when using it on this target group.
Other special note:
Use caution when using the drug for the elderly in very hot or very cold weather because it can cause an increase or decrease in temperature. The drug may interfere with skin tests for allergens. While using Alimemazine, avoid taking it with alcohol and other CNS depressants.
6. Drug interactions
The drug may interact with some other drugs or preparations:
Combined with alcohol, barbiturates increase the CNS depressant effect, in addition, it also causes respiratory depression. The combination enhances the effect of antihypertensive drugs, alpha-adrenergic receptor blockers. Increase anticholinergic effect, reduce psychotic effect when combined with other anticholinergic drugs. Antacid effects with some drugs: Amphetamine, Levodopa, Adrenalin,... Decreased absorption when combined with Antacids, Parkinson's drugs, Lithium. Acute encephalopathy may occur with concomitant use, especially with high doses of Lithium. Inform your doctor/pharmacist about any health-promoting foods and medicines you are taking for advice on possible interactions.
Storage conditions:
Store in a cool, dry place, away from direct sunlight. Storage temperature below 30 degrees C. Keep out of reach of children.
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