Milgamma N is formulated as an injectable solution. It is used to treat neurological conditions such as neuritis, cervical syndrome, optic neuritis, and shingles.
1. What is Milgamma N and What Does It Do?
Milgamma contains key active ingredients such as thiamine hydrochloride, pyridoxine hydrochloride, and cyanocobalamin, formulated as an injectable solution. Milgamma N is indicated for use in the following cases:
- Neurological conditions of various origins
- Neuritis
- Polyneuritis (due to diabetes, alcoholism, etc.)
- Cervical syndrome
- Shoulder-arm syndrome
- Optic neuritis
- Shingles
- Neurological and hematological symptoms due to vitamin B1, B6, and B12 deficiencies when oral treatment is not suitable
Milgamma N is contraindicated for individuals with known hypersensitivity to its active ingredients.
2. How to Use and Dosage of Milgamma N
How to Use: Administer the medication intramuscularly. Milgamma N should be administered as a deep intramuscular injection.
Dosage: To quickly achieve high blood levels of the medication in severe and acute pain cases, start with an injection of 2ml/day. After the acute phase has subsided and in less severe cases, inject 2-3 times/week. During the injection process, the doctor should monitor the patient's treatment weekly and try to switch to oral treatment as soon as possible.
*Note: The above dosage of Milgamma is for reference only. Based on the patient's condition and disease progression, the doctor will prescribe the most appropriate dosage.
- Overdose: In case of overdose, the patient will receive immediate treatment support.
- Missed Dose: Milgamma N is used in medical facilities under the supervision and monitoring of healthcare professionals, so missed doses are rare.
3. Side Effects of Milgamma N
When using Milgamma N, patients may experience some unwanted side effects such as:
- Immune system disorders: Hypersensitivity reactions (skin rash, shock, angioedema, respiratory distress)
- Nervous system disorders: Dizziness, decreased concentration
- Cardiac disorders: Tachycardia or bradycardia, arrhythmia
- Gastrointestinal disorders: Vomiting
- Skin and subcutaneous tissue disorders: Excessive sweating, acne, itching, urticaria
- Musculoskeletal and connective tissue disorders: Muscle cramps
- Common injection site disorders: Systemic reactions may occur due to rapid flow (unintentional intravenous injection or injection into highly vascularized tissue) or overdose
In the event of side effects, patients should discontinue Milgamma N immediately, inform their doctor, or seek prompt medical attention at the nearest healthcare facility.
4. Precautions When Using Milgamma N
Before using the medication, read the instructions carefully and consider the following information:
- Milgamma N is only for intramuscular injection, not for intravenous injection. If injected intravenously, it should be monitored by a doctor or in a hospital setting, depending on the severity of the symptoms.
- Milgamma N can cause neurological disorders if used for more than 6 months.
- Milgamma contains sodium but less than 1 mmol (23mg) of sodium per dose (2ml).
- Milgamma N is not indicated for use in children under 12 years old.
- Milgamma N has no special recommendations for the elderly.
- Avoid administering vitamin B6 doses exceeding 25mg per day in pregnant or breastfeeding women. Since Milgamma N contains 100mg/2ml ampoule, it should not be used in this group.
5. Drug Interactions with Milgamma N
Some drug interactions with Milgamma N to note:
- Thiamine is completely degraded by solutions containing sulfite.
- Other vitamins may be inactivated in the presence of vitamin B1 degradation products.
- Vitamin B6 dosage may reduce the effectiveness of L-dopa.
- The medication interacts with INH, cycloserine, and D-penicillamine.
- Milgamma N should be stored at 2°C to 8°C in a refrigerator, protected from excessive heat and direct light.
Before using Milgamma N, patients should inform their doctor about any medications they are currently using. If any side effects occur, patients should notify their doctor immediately for early examination and treatment.
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