Uses of the drug Ferlatum

This is an automatically translated article.

Ferlatum drug is manufactured with the main ingredient including iron compounds. The drug is effective in the prevention and treatment of iron and folate deficiency, or hypochromic red blood cells or isochromic anemia... However, in some cases, drug use may experience undesirable side effects such as diarrhea, nausea... Therefore, before using the drug you should learn carefully and get advice from a doctor.

1. Pharmacodynamics and pharmacokinetics of Ferlatum

1.1. Pharmacodynamics of the drug ferlatum fol The iron component ferlatum fol is formed by combining with folinic acid and an iron and protein complex. The compound ferlatum fol is obtained from the succinylation of milk proteins containing 5% and 0.2% trivalent iron. At the same time, thanks to the soluble properties of iron and protein compounds, succinylate is able to precipitate in the acidic environment of the stomach but still retains the association with iron ions. The iron then begins to re-dissolve in the alkaline environment of the duodenum and allows iron absorption through the intestinal mucosa, while the protein component of the molecule is digested by the pancreatic protease enzyme.
The folinic acids include leucovorin, citrovorum factor in the highly bioactive form of folic acid and also the activity of a real vitamin. When using folate in the form of folinic acid can help avoid metabolic steps and help replenish vitamin reserves that are lacking, although the body still has a deficiency of liver and intestinal enzymes in the process of folic acid metabolism. to a biologically active form. Folinic acid plays an important role in the synthesis of purines and pyrimidines and is also quite essential for DNA synthesis especially at tissue sites during hematopoiesis. At the same time, folinic acid is especially effective in all cases of anemia caused by folate deficiency. The clinical trials conducted with the active ingredients in the drug ferlatum fol showed good anti-anemic activity.
1.2. Ferlatum Fol Pharmacokinetics With common iron compounds, pharmacokinetic studies have shown that often these compounds are not of much benefit because, as is the case, iron is in the protein succinylate compound. The protein component is digested by digestive juices in the stomach, the iron part will also be absorbed depending on the individual's body needs.
However, in products that have been shown to be as well absorbed by research as being taken by mouth, can help quickly achieve blood iron levels. However, then this concentration is always stabilized in homeostasis, even after the use of iron in high doses.
Animal experiments show that iron protein succinylate complex is tested against other common iron compounds, the results of these experiments show better iron absorption and increase blood iron levels higher and longer.
Under normal conditions, the amount that will be lost is very limited. Most iron can be eliminated through the menstrual cycle or in small amounts through bile, sweat, or possibly through shedding of the skin. By using calcium folinate with 14C and 3H linkages, the results were found to be similar to those of microbiological quantification.

2. Uses, dosage and usage of ferlatum fol

2.1 Uses of the drug Ferlatum fol Ferlatum fol is indicated for use in cases such as prevention and treatment of iron or folic acid deficiency. In addition, ferlatum fol can also be used for people with symptoms of hypochromic or characteristic anemia or anemia or macrocytic anemia or megaloblastic anemia in children, secondary iron deficiency. development due to inadequate supply/reduced absorption of iron/synthetic folic acid.
Besides, pregnant and lactating women can also be prescribed iron supplements during childbirth and breastfeeding.
2.2. Dosage and use of the drug Ferlatum fol Ferlatum fol is used orally. Adults can use with oral doses from 1 to 2 types a day as prescribed by the doctor. It is best to use the medicine before meals.
For children, use an oral dose of 1.5mg/kg/day as prescribed by the treating doctor and should be taken before meals.
Treatment with ferlatum fol will usually continue until the body's iron stores reach the normal threshold. The duration of iron deficiency treatment with ferlatum fol can be extended from 2 to 3 months.
Ferlatum fol used the maximum daily dose according to clinical studies showing, efficacy and tolerability of ferlatum fol has been performed in humans with adult doses of 80mg iron/day, children 4mg iron/day. day. However, with larger doses, specific data on tolerability and clinical efficacy are not available.
However, the above dosage is for reference only. To use the drug effectively during treatment, you should consult your doctor and use the drug as prescribed by the treating doctor.
In case of overdose with ferlatum fol, iron salts can cause patients to have epigastric pain, nausea, vomiting, diarrhea or may vomit blood, and may be accompanied by some symptoms such as drowsiness, pale skin or cyanosis. Even an emergency overdose can cause coma. If the overdose is severe, the patient should use more anti-emetics or fluids to clear the stomach. In case of emergency, it is necessary to take the patient to the emergency room at the nearest medical facility to avoid a possible bad condition.

3. Unwanted side effects when using ferlatum fol

In addition to the benefits that ferlatum fol can provide to patients, in some cases it may be contraindicated to the drug such as: patients are hypersensitive to the ingredients of the drug or the excipients included in the drug. . People with hemosiderin or tissue iron deficiency anemia, aplastic megaloblastic anemia or iron deficiency anemia.
Ferlatum fol can cause some undesirable although rare side effects such as diarrhea, constipation, nausea or epigastric pain. Or you may experience black or dark gray stools. Therefore, the patient can stop using the drug and notify the doctor to adjust the dose.
Using ferlatum fol does not have the risk of familiarity or dependence on the drug. However, you should not use the drug for more than 6 months if you have prolonged bleeding or polymenorrhea or are pregnant.
Furthermore, caution should be exercised when using the drug in patients who are intolerant to milk proteins or may have allergic reactions in these patients.
Knowing the information about the drug Ferlatum will help patients use the drug for the right purpose and achieve better treatment effects.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.