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Tedavi 312.5mg is an antibiotic used in the treatment of infections caused by beta-lactamase-producing bacteria that are unable to respond to treatment with penicillin alone. However, the drug is only used for a short time (less than 14 days) to avoid adverse effects on health.1. What is Tedavi 312.5mg?
Tedavi 312.5mg is an antibiotic containing Amoxicillin (in the form of Amoxicillin trihydrate) 250mg; Clavulanic acid (as Potassium clavulanate diluted with silica 1:1) content 62.5mg.
In this table of ingredients, Amoxicillin is a semi-synthetic antibiotic of the beta-lactam family with a broad bactericidal spectrum, effective against a wide range of Gram-positive and Gram-negative bacteria by inhibiting bacterial cell wall synthesis. It is worth noting that the active ingredient Amoxicillin is very easily degraded by lactamase enzymes, so it has no effect on these yeast-producing strains.
With Clavulanic Acid, this is a high-affinity active ingredient and binds to a number of competitive, reversible lactamases. Their structure is similar to that of Penicillins and Cephalosporins, providing high efficiency in inhibiting lactamase enzymes.
Clavulanic acid protects Amoxicillin from being degraded by lactamases, and also extends the antibacterial spectrum of Amoxicillin to be effective against many bacteria that normally produce lactamases resistant to Amoxicillin when used alone.
2. Indications and contraindications Tedavi 312.5mg
2.1. Indications Tedavi 312.5mg Tedavi 312.5mg is indicated for use in the following cases:
Patients with severe upper respiratory tract infections commonly in diseases such as tonsillitis, sinusitis, otitis media have been used. Conventional antibiotics are not effective. People with lower respiratory tract infections caused by strains of H. influenzae and Moraxella catarrhalis producing beta-lactamase are common in acute and chronic bronchitis, pneumonia - bronchiolitis. Patients with severe infections of the urinary tract - genitourinary by strains of E.coli, Klebsiella and Enterobacter sensitive beta-lactamase producing common in diseases such as cystitis, urethritis, pyelonephritis. People with skin and soft tissue infections such as boils, insect stings, abscesses, infected wounds, cellulitis. Bone and joint infections in people with osteomyelitis. Dental infections lead to alveolar abscesses. Other infections such as obstetric and abdominal infections, after miscarriage. 2.2. Contraindications Tedavi 312.5mg Although the effect of Tedavi is undeniable. However, you should note that the drug is contraindicated in the following cases:
The patient is allergic to penicillin or cross-allergic to Cephalosporin. People with infectious mononucleosis or lymphocytic leukemia should not take the drug.
3. Dosage and how to use Tedavi 312.5mg
3.1. Dosage of Tedavi 312.5mg The usual dose of Tedavi 312.5mg is 250mg - 500mg (calculated according to Amoxicillin), every 8 hours. For children under 10 years old, a dose of 125-250mg can be used every 8 hours. For children under 20kg, it is usually recommended to use a dose of 20-40mg/kg body weight/day. In some cases, the drug Tedavi 312.5mg is used in a high and single dose such as:
Treatment of tooth abscess using a dose of 3g, repeated again after 8 hours. Treatment of acute urinary tract infections uncomplicated using Tedavi 312.5 mg dose 3g, repeated after 10-12 hours. Prophylaxis of endocarditis using only 3g. Patients with severe or recurrent respiratory tract infections use a dose of 3g Amoxicillin twice a day. 3.2. How to take Tedavi 312.5mg First, gently tap the bottle to help the entire amount of powder flow to the bottom of the bottle. Pour cooled boiled water into the bottle with the amount of water reaching the mark marked on the bottle, then shake vigorously to dissolve the powder into the water. Add water if necessary so that the volume of suspension reaches the marked mark and use.
4. Tedavi drug side effects 312.5mg
When using Tedavi 312.5mg, some common side effects include diarrhea, stomach pain, vomiting, skin rash, itching, hives, difficulty breathing. In some cases, signs of difficulty swallowing, wheezing, itching and vaginal discharge, yellowing of the skin or eyes may occur. There are also some other rare side effects, so call your doctor if you notice any unusual problems while taking the medicine.
5. Tedavi drug interactions 312.5mg
Concomitant use with Probenecid increases the concentration of Amoxicillin in the blood, so it should be avoided. Concomitant use of anticoagulants may prolong prothrombin time abnormally, so the dose of oral anticoagulants should be adjusted. Concomitant administration of Allopurinol resulted in a significant increase in the incidence of rash in patients. Concomitant use with oral contraceptives may affect the intestinal microflora, leading to a significant reduction in the effectiveness of oral contraceptives. Amoxicillin in Tedavi 312.5mg may lead to a false positive reaction when a urine glucose test is performed.
6. Be careful when using Tedavi 312.5mg
Patients with a history of cholestatic jaundice or liver dysfunction, severe renal failure or on hemodialysis should be cautious when using the drug. Tedavi 312.5mg should be used during pregnancy only when clearly needed. Tedavi 312.5mg is excreted in breast milk, so it should be used with caution in nursing mothers. Renal function should be monitored in the elderly when using Tedavi 312.5mg. Above is some reference information about the drug Tedavi 312.5mg. Because Tedavi 312.5mg is a prescription drug, patients should not use it on their own, but need to contact a specialist directly for a suitable prescription to ensure safety for health.
