Uses of Samarin 70

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1. What is Samarin 70?

What is Samarin 70 drug? The drug Samarin 70 has the main active ingredient is Silymarin with a content of 70mg and other excipients in a sufficient amount. This is a medicine to treat diseases of the digestive tract, specifically treating acute and chronic hepatitis; treatment of cirrhosis,...
Samarin 70 is made in the form of film-coated tablets, suitable for direct oral use. Packing is a box of 3 blisters, 10 blisters or 25 blisters, each blister contains 10 tablets. Silymarin is a mixture of flavonolignans extracted from milk thistle, which has been used to treat jaundice or biliary tract disorders.
Active ingredient Silymarin has the effect of stabilizing cell membranes, preventing the penetration of toxins into liver cells, helping cells not to be penetrated and destroyed by toxins, so this active ingredient Strengthens cell membranes and maintains cell structure and function. Silymarin has the effect of inhibiting the transformation of the liver into fibrous tissues, reducing the formation and deposition of collagen fibers that lead to cirrhosis.
In addition, active ingredient Silymarin also protects liver cells, enhances liver function and stimulates the growth of new liver cells to replace old damaged liver cells, stimulates the recovery of old liver cells. damaged liver cells as well as have anti-lipid peroxidation, anti-inflammatory effects. Thereby, it is used to improve signs and symptoms of liver disease, reduce the concentration of liver enzymes in the blood.
Active ingredient Silymarin has the following effects:
Enhance liver detoxification function. Increased production of cytochrome P450 in the endoplasmic reticulum plays an important role in the detoxification mechanism of hepatocytes. Stimulates regenerative activity of hepatocytes, increases liver mass and microsomal protein. Enhances the immunogenic response and is significantly effective in liver damage caused by immunotoxic agents such as: CCl4, ketoconazole. Protect liver cells from damage caused by toxins such as alcohol, drugs that are toxic to the liver (Acetaminophen, antibiotics, antifungals, cancer drugs, birth control pills...).

2. What disease is Samarin 70 used to treat?

Samarin 70 is used in the treatment of digestive dysfunction related to liver diseases, specifically as follows:
Treatment of acute and chronic hepatitis. Treatment of cirrhosis. Treatment of fatty liver that is not caused by alcohol. Treatment of bacterial hepatitis. Treatment of liver disease caused by alcohol use. Injury to the liver is caused by metabolic toxicity, namely fat infiltration into the liver, toxicity from fungi. Protect liver cells and restore liver function for people who drink alcohol, beer, food poisoning, chemicals. Protect liver cells for people who are using drugs that are harmful to liver cells such as drugs for treatment of tuberculosis, cancer, diabetes, drugs affecting nerves, non-steroidal anti-inflammatory drugs... Treatment of liver dysfunction with symptoms of fatigue, anorexia, dyspepsia, jaundice, allergies, urinary retention, constipation... Prophylaxis and supportive treatment in cirrhosis of the liver, Liver Cancer.

3. Usage and dosage of the drug Samarin 70

3.1. How to take the drug Samarin 70 Samarin 70 is prepared in the form of film-coated tablets, suitable for direct oral use.
3.2. Dosage of the drug Samarin 70 Dosage to protect the liver: 420mg / day divided into 3 times a day for a period of 6 to 8 weeks then maintain the dose of 280mg / day. Dosage for toxicity from fungi: 33mg/kg/day. 3.3. Cases of drug overdose Samarin 70 Currently, information on overdose of drug Samarin 70 is still limited. Treatment is symptomatic and functional support. There have been no reports of toxicity following an overdose of Samarin 70. Gastrointestinal lavage is generally not recommended, except in the case of large doses of the drug or concomitant use of other toxins.

4. Undesirable effects of the drug Samarin 70

Undesirable effects of Samarin 70 may occur during use as follows:
Active ingredient Silymarin is well tolerated by the gastrointestinal tract. However, during the use of the drug, you may still experience some unwanted effects such as flatulence, bloating, nausea, headache, diarrhea, indigestion, abdominal pain or loss of appetite. At the same time, may cause a reaction with the active ingredient Silymarin. You need to proactively inform the treating doctor of any unwanted effects that may occur during treatment with Samarin 70.

5. Drug interactions of Samarin 70

During the use of Samarin 70, some drug interactions may occur, specifically as follows:
Metronidazol: Using metronidazol in combination with Samarin 70 significantly increases the elimination of Metronidazol and significantly reduces the significantly exposed to metronidazole. In cases where it is necessary to use the combination, it is necessary to increase the therapeutic dose of Metronidazol

6. Some notes when using Samarin 70

6.1. Contraindications of the drug Samarin 70 Contraindications of the drug Samarin 70 in the following cases:
People with hypersensitivity or sensitivity to the main active ingredient Silymarin or other ingredients in the drug. The use of Samarin 70 is not recommended for pregnant and lactating women, due to the lack of data on its use in this population. Contraindicated for use in patients with cholecystitis. 6.2. Use of Samarin 70 with other special subjects Using of Samarin 70 with pregnant and lactating women: Scientific evidence on safety when used for pregnant women and children breastfeeding has not been clearly studied. Therefore, Samarin 70 should not be used with this group of subjects.
Above is all information about Samarin 70, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Samarin 70 to treat diseases at home, because there may be unwanted side effects on health.
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