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Rivotril 2mg is a drug containing the main ingredient is Clonazepam with the effect of treating neurological diseases. The following article will introduce you to some information and instructions for using this drug.
1. What is Rivotril 2mg?
Rivotril 2mg is a drug manufactured with the main active ingredient is Clonazepam with a strength of 2mg and accompanied by other excipients just enough for one tablet.
Mechanism of action of the drug through its ability to inhibit GABA-mediated postsynaptic. Several animal studies and human EEGs have shown that clonazepam contained in rivotril helps to reduce overactive brain waves in patients with epilepsy.
Active ingredient Clonazepam can be completely absorbed quickly after oral administration. Peak plasma concentrations are reached 1-4 hours after oral administration and bioavailability is up to 90%. The plasma binding capacity of Rivotril is 85% and Clonazepam is excreted in human milk through the placenta.
2. What are the effects of Rivotril 2mg?
What does Rivotril 2mg do? Rivotril belongs to the group of benzodiazepines with sedative, anticonvulsant, anxiolytic and muscle relaxant properties. In addition, the drug also helps to improve the imbalance of neurotransmitters to treat certain types of epilepsy, including Lennox-Gastaut syndrome, absence of consciousness or panic and anxiety disorders in adults and children.
3. Instructions for using Rivotril 2mg
The drug is taken orally at any time of the day regardless of the presence of food. Depending on the disease and the characteristics of the patient, the doctor will prescribe the appropriate dose. Reference dosages are given as follows:
3.1. Epilepsy For adults:
Use the starting dose is 1mg, the elderly can reduce to 0.5mg, the maximum dose is 1.5mg / day divided into 3 times / day. May increase to approximately 0.5-1 mg every 3 days until seizures are controlled. The maintenance dose is in the range of 4-8 mg/day divided into 3 times/day. The maximum allowable dose is 20mg/day. Children and young children
Start with a dose of 0.01 - 0.03 mg/kg/day, divided into 3 times. Increase dose to no more than 0.25-0.5 mg/day every 3 days. Maintenance dose: 0.1-0.2 mg/kg/day, divided into 3 times. The maximum allowable dose is up to 0.2 mg/kg/day. 3.2.People with panic disorder Adults
Start with a dose of 0.25mg/time, take 2 times/day. The dose may be increased to 1 mg/day every 3 days. When stopping treatment, it is necessary to reduce the dose gradually, every 3 days, reduce 0.125 mg until completely stopped.
4. Contraindications of Rivotril 2mg
Rivotril 2mg is contraindicated in the following cases:
Patients with a history of hypersensitivity to any of the benzodiazepine components of the drug People with liver disease or acute angle-closure glaucoma.
5. Undesirable effects of Rivotrile
Undesirable effects of Rivotril are as follows:
Some common reactions: Behavioral disturbances, coordination disorders, drowsiness, decreased intellectual ability, constipation, abdominal pain, dysmenorrhea, . Less common symptoms include migraine, weight gain, increased salivation, gastroenteritis, edema, paresthesia, migraine, tremor, arthralgia, gastrointestinal disturbances, insomnia, nightmares , anxiety, irritability, irritability, decreased ejaculation, menstrual disorders, palpitations, breast pain, sexual dysfunction. If you notice any unusual symptoms in your body, you should immediately notify your doctor for timely treatment.
6. Interactions between Rivotril and other drugs
The drugs Phenytoin, Carbamazepine, Phenobarbital when used at the same time can increase the metabolism of Clonazepam leading to a decrease in the concentration of the drug in the blood plasma. Alcohol, anesthetics, hypnotics, anti-renal agents, monoamine oxidase inhibitors, other anticonvulsants, and anxiolytics may potentiate the CNS depression. Inhibitors of CYP P450 3A should be used with caution in combination due to the risk of metabolic changes.
7. Some notes when using Rivotril 2mg
During the use of Rivotril 2mg, patients should note:
Patients need to consult a specialist or health care professional before using Rivotril. It is important to fully report any medications or foods to which the patient has been allergic. Currently, there are no adequate studies on the safety of Rivotril 2mg in pregnant or lactating women. Therefore, patients should carefully consult a doctor before use to weigh the benefits and possible risks. In addition, some patients need to be careful when using the drug, including:
People with spinal or cerebellar ataxia. People with a history of alcohol or drug addiction. People who are suffering from diseases that cause severe liver damage such as cirrhosis. Patients with respiratory diseases such as COPD or liver disease and in patients receiving treatment with centrally acting drugs or anticonvulsants. To be safe and effective, patients should tell their doctor about all medications they are taking.
Rivotril 2mg is a drug containing the main ingredient is Clonazepam with the effect of treating neurological diseases. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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