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Rabe-g is a drug that reduces gastric acid secretion, helps relieve gastrointestinal symptoms caused by increased gastric acid and quickly heals ulcers in the digestive tract.1. What is Rabe-g?
Rabe-g drug has the main ingredient is Rabeprazole sodium 20mg, prepared in the form of enteric-coated film-coated tablets. Rabeprazole is an H+, K+ - ATPase inhibitor (proton pump inhibitor). Rabeprazole sodium inhibits gastric acid secretion after stimulation by agents such as dibutyl cyclic AMP in the gastric glands, histamine or pentagastrin in animals. Reversal of the antisecretory activity of Rabeprazole sodium was more responsive and the elevation of blood gastrin levels was lower with Rabeprazole sodium than with other proton pump inhibitors. Rabeprazole sodium has been shown to have potent anti-ulcer activity against a variety of ulcers and to help improve experimental gastric mucosal injuries (cold stress, immersion stress, pyloric spasm, cysteine or ethanol-HCl).
2. What does Rabe-g do?
Thanks to the effect of reducing gastric juice secretion and anti-ulcer, Rabe-g is indicated for use in the following cases:
Stomach ulcer, duodenal ulcer, mouth ulcer. Gastroesophageal reflux. Zollinger-Ellison syndrome. Contraindications: Do not use for people with hypersensitivity to the components of the drug or derivatives of benzimidazole.
3. Dosage and how to use Rabe-g
How to use: The drug is taken with water. The film-coated tablets dissolve in the intestines when taken, so the patient should swallow the tablet whole. The patient should not chew, crush or break the tablet. Rabe-g can be taken with or without food. It is best to take the drug before meals or at bedtime to reduce gastric acid secretion due to meals or at night.
Dosage:
For adults:
Gastroesophageal reflux disease (GERD): Take 1 20 mg tablet once a day, within 4-8 weeks, can be used more after taking 8 weeks as needed. Duodenal ulcer or gastric ulcer 1 tablet 20 mg once a day for 4 weeks. Most patients heal their duodenal ulcer within 4 weeks of taking the drug. Some patients may need another course of treatment to heal the ulcer. Zollinger-Ellison syndrome is initiated at 60 mg once daily, titrated according to individual patient response. Combination of antibiotics in the treatment of Helicobacter pylori infection: Depending on each regimen, there is a different dose combination. Children: Do not give this medicine to children, because there is no experience and the safety and effectiveness of this medicine are unknown.
Patients with liver failure: need to adjust the dose accordingly as prescribed by the doctor.
4. Side effects of Rabe-g
When taking Rabe-g you may also experience some side effects including:
Weakness, fever, chills, fatigue; Allergic reactions such as rash, urticaria, itching... Chest pain below the sternum, stiff neck, photosensitivity; Digestive disorders, dry mouth, belching, rectal bleeding, black stools, abdominal distension, loss of appetite, gallstones, gingivitis, glossitis, cholecystitis; Increased appetite; Colitis, esophagitis, pancreatitis may also occur; Changes in hematological indicators, affecting liver function. When taking this medicine if you experience side effects, monitor and tell your doctor right away if the side effects persist or are severe.
5. Pay attention when using Rabe-g
Before taking the drug, you need to understand the uses, ingredients, and at the same time tell your doctor about the history of allergies and accompanying diseases.
Because drugs when taken orally can reduce symptoms, delay the time to diagnose malignancy. Therefore, before taking the drug you need to rule out the possibility of malignancy in the stomach.
Caution when using the drug:
Pregnant and lactating women: Because the effect of the drug on the fetus or nursing child is unknown, pregnant or lactating patients should only use it when indicated by the doctor. doctor and have carefully weighed the benefits and risks for the fetus or nursing infant. People with liver failure: For people with liver failure due to drugs metabolized by the liver should be very careful when using. Treatment with proton pump inhibitors, including rabeprazole, may increase the risk of gastrointestinal infections due to decreased gastric pH, increased bacterial infections such as Salmonella, Campylobacter and Clostridium difficile. Pay attention to a diet that ensures food hygiene and safety to avoid the risk of gastrointestinal infections.
Interaction of Rabe-g with other drugs:
Caution should be exercised when taking Rabeprazole with drugs such as Digoxin. When taking Rabeprazole, the body reduces the production of gastric acid, so the pH of the stomach increases. Since blood levels of digoxin may be increased due to increased absorption of digoxin and as gastric pH increases. Thereby increasing the risk of Digoxin poisoning for patients, so it is necessary to pay attention to this combination. Phenytoin: It has been reported that the use of a rabeprazole analogue (omeprazole) has prolonged the metabolism and excretion of phenytoin. Co-administration of Rabe-g with ketoconazole or itraconazole: Absorption of ketoconazole or itraconazole may be reduced. Therefore, if co-administered, it may be necessary to monitor and adjust the dose of ketoconazole or itraconazole. In addition, during use may occur interactions with other drugs. Therefore, you should carefully read the manufacturer's instructions or inform your doctor about the medicine you are taking
Storage: The medicine should be stored in a cool, dry place, the temperature is below 25 degrees Celsius. out of reach of children.
Hopefully, with the above information, you already know the uses of Rabe-g, dosage, usage and things to note when taking the drug. This is a prescription drug and is to be taken under the direction of a doctor. You need to follow the treatment instructions exactly and do not use it on your own.
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