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Rablet B comes in tablet form, the main ingredient is rabeprazole sodium 20mg. The drug is used in the treatment of gastroduodenal ulcers, maintenance treatment of ulcers caused by gastroesophageal reflux - oesophagitis, long-term treatment of pathological hypersecretory conditions including Zollinger - Ellison syndrome.
1. What is Rablet - B?
Rablet-B is made in the form of tablets, with the main ingredient being rabeprazol sodium 20mg. It is a benzimidazole derivative that inhibits the proton pump, which inhibits gastric acid secretion. In gastric parietal cells, the sulfonamide active form of Rabeprazole has the ability to inhibit H +, K + ATPase enzymes, preventing the final stage of gastric acid secretion.
Rablet - B is used in the treatment of peptic ulcers, the maintenance treatment of ulcers caused by gastroesophageal reflux disease, the long-term treatment of pathological hypersecretory conditions including Zollinger's syndrome - Ellison.
2. Dosage-How to take the drug Rablet - DISCLOSURE
The drug is to be taken orally, with appropriate amounts of water. Dosage is divided as follows:
Treatment of ulcers caused by gastro-oesophageal reflux: Adults take 1 tablet per day for 4 to 8 weeks continuously. Maintenance treatment of ulcers caused by gastroesophageal reflux - oesophagitis: Take 1 tablet/day. Kill H.pylori bacteria: Combine for 7 days with Rabeprazol 20mg, Clarithromycin 500mg, Amoxicillin 1g. Drink each type 2 times/day. Treatment of pathological hypersecretion including Zollinger Ellison syndrome: Adults take 3 tablets/time/day. Dosage is adjusted according to need and can be up to 6 tablets / day. Dose of 5 tablets/day can be taken 1 time. Patients with renal impairment, the elderly: No dosage adjustment necessary Children: Safety and efficacy have not been established.
3. Contraindications to the use of Rablet - B
Rablet - B is not used for people who are sensitive to any of the ingredients or other Benzimidazole derivatives.4. Side effects of the drug Rablet -
Some possible side effects during the use of Rablet-B include:
Common: Cough, weakness, diarrhea, nausea, nonspecific pain, insomnia, infection, headache, apple constipation, rhinitis, abdominal pain, pharyngitis, flatulence, back pain, flu-like syndrome, vomiting. Uncommon: Erythema, chest pain, bronchitis, restlessness, urinary tract infection, belching, arthralgia, somnolence, dry mouth, fever, sinusitis, dyspepsia, chills, myalgia, increased enzymes liver. Rare: Acute systemic allergic reactions, visual disturbances, neutropenia, depression, thrombocytopenia, hepatitis, pruritus, weight gain, anorexia, leukopenia, hepatic encephalopathy, inflammation stomach, increased sweating, leukocytosis, jaundice, bullous rash, interstitial nephritis. Very rare: Stevens - Johnson syndrome, toxic epidermal necrolysis, erythema multiforme.
5. Drug Interactions Rablet - OVER
Possible drug interactions when Rablet-B is used with the following drugs:
Decreases the bioavailability of Ketoconazole Causes an increase in the peak plasma concentration and AUC of Digoxin Increases INR and Prothrombin time, May lead to abnormal bleeding and death when used with Warfarin To avoid adverse interactions that affect the effectiveness of treatment, tell your doctor about all medications you are taking.
6. Be careful when using the drug Rablet - DISCLOSURE
Some notes in the process of taking the drug include:
Caution when used for pregnant and lactating women, because there are no adequate clinical studies on these subjects Rablet - B is only prescribed and sold. Prescription The possibility of cancer should be ruled out before using the drug because improvement of symptoms with the drug can delay the cancer diagnosis Long-term treatment should be regularly checked Caution when starting treatment for patients with severe liver failure In summary, Rablet B is available in tablet form, the main ingredient is rabeprazole sodium 20mg. The drug is used in the treatment of gastroduodenal ulcers, maintenance treatment of ulcers caused by gastroesophageal reflux - oesophagitis, long-term treatment of pathological hypersecretory conditions including Zollinger - Ellison syndrome. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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