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Phagofi 4 is a medicine that works to prevent the risk of bronchial asthma, bronchospasm or symptoms of allergic rhinitis. When used prophylactically, the drug has been shown to be effective in reducing acute asthma attacks and asthma severity.
1. What are the effects of Phagofi 4?
Phagofi 4 has the main ingredient Montelukast (in the form of Montelukast sodium) with a concentration of 4mg, prepared in the form of tablets.
Montelukast has an inhibitory effect on the inflammatory substance leukotriene. Leukotrienes are normally produced by the body when the body is exposed to allergens, thereby creating an inflammatory response that causes an increase in respiratory secretions, constriction of the muscles around the airways, and seizures. asthma . When used, the drug can prevent and reduce exacerbations of bronchial asthma, symptoms of allergic rhinitis and exercise-induced bronchospasm.
2. Indications and contraindications of Phagofi 4
Phagofi 4 is used in the following cases:
Prophylaxis and treatment of chronic bronchial asthma in adults and children from 6 months of age and older, including prevention of daytime and nighttime asthma symptoms Treatment of aspirin-sensitive asthmatics and prevention of exercise-induced bronchospasm. Relieving day and night symptoms of allergic rhinitis (seasonal allergic rhinitis in adults and children 2 years of age and older and perennial allergic rhinitis in adults and children 6 months of age and older). up). Contraindications:
Hypersensitivity to any of the components of the drug.
3. Dosage and how to use Phagofi 4
How to use: The drug is taken orally once a day on full or empty stomach.
To cure asthma, it is recommended to take the medicine at night before going to bed. For people with allergic rhinitis, the duration of medication can depend on the needs of each patient. For patients with both asthma and allergic rhinitis, it should be taken every day at night before going to bed. The therapeutic effect of Montelukast on asthma test parameters is achieved within 1 day. Montelukast should be continued despite asthma control, as well as during periods of more severe asthma. Dosage:
Asthma:
Children from 2 to 5 years old: Take 1 tablet 4mg; Children 12 - 23 months old: Take 1 4mg tablet by grinding finely and then mixing with water or using powder sachets. Seasonal allergic rhinitis:
Children from 2 to 5 years old: Take 1 tablet 4mg orally. Dosage in the treatment of patients with symptoms of year-round allergic rhinitis:
Children from 2 to 5 years old: Take 1 tablet 4mg; Children from 6 to 23 months old: Take 1 4mg tablet by crushing the tablet and then mixing it with water or it should be used in the form of granules or powder for oral administration. Patients with asthma and allergic rhinitis: Take 1 tablet daily in the evening.
No dosage adjustment is required for patients with mild and moderate renal/hepatic impairment, the elderly, or intersex.
4. Side effects of the drug Phagofi 4
Some possible side effects when taking the drug include:
Upper respiratory tract infections such as rhinitis, sinusitis, inflammation, tonsillitis...; Increased risk of bleeding such as nosebleeds; Possible hypersensitivity reactions include anaphylaxis, hepatic eosinophilic infiltration; Dizziness, drowsiness, paresthesias such as numbness, tingling, decreased sensation, seizures; Palpitations; Diarrhea, dry mouth, slow digestion, indigestion, nausea, vomiting; Increased serum ALT(GPT), AST(GST), hepatitis (including cholestasis, hepatocellular inflammation, mixed liver injury); Angioedema, bruising, urticaria, itching, rash, erythema nodosum; Joint pain, muscle pain, sometimes cramps; Weakness, frequent fatigue, malaise or fever; Mood changes including depression, anxiety, increased self-harm or suicidal thoughts. It is necessary to monitor throughout the course of taking the drug, especially in children and adolescents. When using the drug, if you see the above side effects, you should notify your doctor or go to a medical facility for treatment.
5. Things to pay attention to when taking Phagofi 4
Montelukast can be used in combination for patients who are on other treatment regimens. May reduce the dose of drugs in combination with bronchodilators, inhaled or oral corticosteroids. Montelukast should not be abruptly substituted for inhaled or oral corticosteroids. Closely monitor the patient's clinical signs when reducing the dose of systemic corticosteroids in patients receiving Montelukast. Do not use concurrently with other products containing the same ingredients as montelukast. Do not use to treat acute asthma but need to use medicines that relieve asthma. You still use Montelukast during the scheduled day to prevent an asthma attack. People with galactose intolerance, the Lapp lactase defect, glucose-galactose malabsorption should not take the drug. Drug Interactions: Caution should be exercised when co-administering drugs, especially in children co-administering CYP3A4 inducers (eg, Phenytoin, Phenobarbital, Rifampicin). Storage: Store the medicine in an airtight container, away from moisture and out of direct light. Phagofi 4 is used to prevent the occurrence of bronchial asthma, bronchospasm or symptoms of allergic rhinitis. This is a prescription drug, so you should consult your doctor before taking it.
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