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Orela 25mg drug is indicated in the treatment of essential hypertension, angina pectoris, congestive heart failure. To use the drug effectively, patients need to learn some information about the uses, dosage and notes when using Orela 25mg in the article below.
1. What is Orela 25?
Orela 25mg belongs to the group of cardiovascular drugs, prepared in the form of film-coated tablets, packing specifications: Box of 10 blisters x 10 tablets. The ingredient Carvedilol 25mg in Orela 25 is a racemic mixture that selectively blocks alfa1-adrenergic receptors and non-selectively beta-adrenergic receptors.
Carvedilol has the main mechanism of action is antihypertensive as follows, vasodilation by selective blocking of alpha1 receptors, thereby reducing peripheral vascular resistance.
2. Indications for taking Orela 25mg
Orela 25mg drug is indicated for use in the following cases:
Essential hypertension; Angina pain ; Congestive heart failure.
3. Dosage, how to use Orela 25mg
Treatment of essential hypertension:
Dosage in adults is 12.5 mg x 1 time / day x 2 days, then 25 mg x 1 time / day. Orela dose can be increased but must be after at least 2 weeks, the maximum dose is 50mg x 1 time / day or 25mg x 2 times / day. Treatment of angina pectoris:
Use Orela dose 12.5mg x 2 times/day x 2 days. Then use the dose of 25mg x 2 times / day, can be gradually increased after at least 2 weeks, the maximum dose of Orela is 100mg / day (divided into 2 times). Treatment of congestive heart failure:
Use Orela dose of 3.125mg x 2 times / day for the first 2 weeks, the dose can be increased gradually after at least 2 weeks to 6.25mg x 2 times / day. Followed by a dose of 12.5 mg x 2 times/day, then 25 mg x 2 times/day, up to a maximum of 25 mg x 2 times/day (patients < 85 kg) and 50 mg x 2 times/day (> 85 kg). . Note: The above dose of Orela is for reference only. The specific dose of Orela will depend on your condition and disease progression. To get the right dose of Orela, patients need to consult their doctor/pharmacist.
4. Contraindications to taking Orela 25mg
Do not use Orela 25mg medicine for the following cases:
People with grade IV heart failure, asthma; Chronic obstructive pulmonary disease (COPD) with bronchospasm; Liver failure; 2nd and 3rd degree atrioventricular block; Heart rate < 50 beats/min; Cardiac shock; Sinus node insufficiency syndrome ; Systolic blood pressure < 85 mmHg; Are allergic to any part or excipient in Orela; Pregnant and lactating women should not take Orela.
5. Drug interactions
Possible interactions when using Orela simultaneously with the following drugs:
Orela enhances the effect of other antihypertensive drugs when used concurrently; Do not combine for intravenous administration with Diltiazem, Verapamil or class I antiarrhythmic drugs; Increase in constant digoxin concentrations when used together; Orela enhances the effect of insulin or oral hypoglycemic agents when used concurrently. To avoid unwanted interactions when using Orela, patients should inform their doctor/pharmacist of all medications, dietary supplements and vitamins... they are taking.
6. Orela . side effects
Side effects of Orela drugs include:
Central nervous system: Dizziness, headache, lightheadedness, fatigue, insomnia, paresthesia. Cardiovascular: Bradycardia, hypotension, fainting, edema, atrioventricular block, heart failure, peripheral circulatory disorders, angina, Raynaud's phenomenon. Digestive system: Nausea/vomiting, diarrhea; Hematology: Reduces platelets and white blood cells; Metabolism: Changes in SGOT and SGPT indexes, hyperglycemia/blood cholesterol. During the course of treatment, if there are any abnormal symptoms suspected of using Orela, the patient should notify the treating doctor/pharmacist for appropriate treatment.
7. Be careful when using Orela 25mg
The following people need to be careful when taking Orela:
Congestive heart failure who are taking Digitalis; People with diabetes, kidney failure, obstructive lung disease; The patient uses contact lenses; Have a history of drug allergy; Psoriasis, adrenal myeloma; Prinzmetal chest pain; Drivers and machine operators. Above is information about the uses, dosage and precautions when using Orela. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Orela exactly as directed by your doctor. Store Orela at room temperature, away from direct sunlight.
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