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Ofloxacin 200mg/100ml is an antibiotic that treats infections in the internal organs of the body. The drug is used as an intravenous infusion for adults and must be used under the direction of a doctor.
1. What is Ofloxacin 200mg/100ml?
Ofloxacin 200mg/100ml is a drug manufactured by Minh Dan Pharmaceutical Joint Stock Company - VIETNAM with registration number VD-31781-19. Ofloxacin medicine 200mg/100ml contains Ofloxacin ingredient with concentration: Each ml of solution for infusion contains 2mg of Ofloxacin 2mg.
Ofloxacin is a fluoroquinolone antibiotic similar to Ciprofloxacin, but Ofloxacin has a bioavailability of more than 95% when taken orally. Ofloxacin has a broad spectrum of antibacterial activity including: Enterobacteriaceae, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria spp., Staphylococcus, Streptococcus pneumoniae and some other gram-positive bacteria. Ofloxacin is more active than Ciprofloxacin against Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma pneumoniae, it is also active against Mycobacterium leprae and Mycobacterium spp. other. Ofloxacin is bactericidal but the mechanism of action is not fully known. Similar to other antibacterial quinolones, Ofloxacin has the ability to inhibit DNA-gyrase, an enzyme necessary for bacterial DNA replication, transcription and repair.
2. What is the use of Ofloxacin?
Ofloxacin 200mg/100ml is indicated for the treatment of the following infections:
Complicated/uncomplicated urinary tract infections; Skin and soft tissue infections; Prostatitis ; Sexually transmitted diseases such as: uncomplicated acute gonococcal infection of the urethra and cervix, non-gonococcal urethritis and cervicitis; Pneumonia caused by H. influenza or by Streptococcus pneumoniae; Chronic bronchitis exacerbation. Comply with the use of Ofloxacin 200mg/100ml according to the instructions written on the drug instruction sheet or the doctor's order.
3. Dosage and how to use Ofloxacin 200mg/100ml
Intravenous infusion of Ofloxacin 200mg/100ml over 30 minutes.
Urinary tract infections: 100 mg x 2 times/day. Lower respiratory tract infections: 200 mg x 2 times/day. Other infections: 200mg x 2 times/day. Gonorrhea: use a single dose of 150 mg. Renal failure ClCr < 20 mL/min: use 1/2 dose.
4. Contraindications of Ofloxacin 200mg/100ml
Ofloxacin 200mg/100ml is contraindicated in patients who are sensitive to Ofloxacin or any other quinolone derivative. Contraindications Ofloxacin 200mg / 100ml is an absolute contraindication, for no reason that contraindication can be flexibly changed to take the drug.
5. Ofloxacin 200mg/100ml side effects
Side effects when using Ofloxacin 200mg/100ml:
Gastrointestinal tract: nausea, vomiting, diarrhea, abdominal pain; Skin: itching, photosensitivity, vasculitis, rash, skin rash; Central nervous system: dizziness, lightheadedness, forgetfulness, tremors, convulsions, paresthesias, increased excitability; Renal: acute renal failure secondary to interstitial nephritis; Other organs: blurred vision, eosinophilia, polymorphonuclear leukopenia, thrombocytopenia, myalgia, gynecomastia. Usually, the side effects or unwanted effects of Ofloxacin 200mg/100ml will go away when the drug is stopped. If there are rare side effects not mentioned in the leaflet, you should immediately inform your doctor or medical person if you suspect that Ofloxacin 200mg / 100ml medicine.
6. Caution and note when using Ofloxacin 200mg/100ml
People who need to be careful before taking Ofloxacin 200mg/100ml: the elderly, pregnant women, nursing mothers, children under 18 years old, people with liver failure, kidney failure, allergic hypersensitivity to any substance In the composition of Ofloxacin 200mg/100ml, subjects with myasthenia gravis, hepatic coma, stomach ulcers ... should consider and consult a doctor or pharmacist before using Ofloxacin 200mg/100ml. The potential benefits and risks should be carefully considered when using Ofloxacin 200mg/100ml in patients with central nervous system diseases including epilepsy and cerebral arteriosclerosis. Photosensitive reactions have been found in some patients being treated with Fluoroquinolones. Patients should avoid exposure to sunlight. In the event of a photosensitivity reaction, Ofloxacin 200mg/kg should be discontinued. 100ml . Patients with impaired renal function need to change their treatment regimen with Ofloxacin 200mg/100ml. Similar to other quinolones, ofloxacin can stimulate the central nervous system causing tremor, restlessness, lightheadedness, confusion and hallucinations..., if present, Ofloxacin 200mg/100ml should be discontinued. and take appropriate treatment measures; When there are signs of tendon pain, the patient should immediately stop taking all fluoroquinolone antibiotics; Patients with a hypersensitivity to a fluoroquinolone antibiotic or to quinolone derivatives with a similar chemical structure may also be sensitized to the active substance Ofloxacin; Consider taking Ofloxacin 200mg/100ml with alcohol, tobacco, alcoholic beverages or fermentation, which can change the ingredients in the medicine.7. Storing Ofloxacin 200mg/100ml
Store Ofloxacin 200mg/100ml at a temperature not exceeding 25 degrees Celsius, avoid moisture and keep out of reach of children. Ofloxacin medicine 200mg / 100ml is usually stored at room temperature, avoiding direct sunlight or high temperature that can metabolize the ingredients in the drug.
Carefully read the instructions for storage of Ofloxacin 200mg/100ml medicine written on the package and instruction sheet, check the expiry date of the medicine. When not using Ofloxacin 200mg/100ml, it is necessary to collect and handle according to the instructions of the manufacturer or the person in charge of medicine.
In summary, Ofloxacin 200mg/100ml is an antibiotic that treats infections in the internal organs of the body. The drug is used as an intravenous infusion for adults and must be used under the direction of a doctor.
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