This is an automatically translated article.
Ofbeat drug is made in the form of film-coated tablets, containing the active ingredient Ofloxacin, which is a Quinolone antibiotic. Ofbeat is indicated in cases of infections caused by susceptible bacteria. Let's find out useful information about the drug through the article below.
1. What is Ofbeat drug? Ofbeat's effects
Ofbeat medicine contains the active ingredient Ofloxacin, which is made in the form of film-coated tablets with a strength of 200mg or 400mg.
Effects of Ofbeat:
Active ingredient Ofloxacin is a Quinolone antibiotic similar to Ciprofloxacin, but the oral bioavailability of Ofloxacin is higher than 95%. Ofloxacin has a broad spectrum of antibacterial activity, including Enterobacteriaceae, Haemophilus influenzae, Neisseria spp., Pseudomonas aeruginosa, Streptococcus pneumoniae, Staphylococcus and a few other gram-positive bacteria. Ofloxacin is more active than Ciprofloxacin against Ureaplasma urealyticum, Chlamydia trachomatis, Mycoplasma pneumoniae. In addition, Ofloxacin is active against Mycobacterium leprae and also Mycobacterium spp. other. Like other antibacterial quinolones, Ofloxacin has a bactericidal effect, inhibiting DNA-gyrase (an enzyme necessary for bacteria in the process of DNA replication, transcription and repair).
2. Indications of the drug Ofbeat
Ofbeat medicine is used in the following diseases:
Severe bacterial bronchitis. Pneumonia. Chlamydia infection of the urethra or cervix, with or without gonorrhea, uncomplicated gonorrhea. Prostatitis. Urinary tract infections. Skin infections, soft tissue infections. Inflammation of the colon due to bacterial infection. Anthrax (Anthrax). Blood infections, bones and joints, obstetrics and gynecology,...
3. Contraindications to the use of Ofbeat
Absolutely do not use Ofbeat drug for patients with a history of allergy to Ofloxacin or other Quinolones and any of its ingredients. Antibiotics with Fluoroquinolone bactericidal mechanism such as Ofloxacin, Ciprofloxacin can cause articular cartilage degeneration in load-bearing joints in experimental animals. Therefore, it is not recommended for children under 18 years of age, pregnant women and women who are breastfeeding. Glucose-6-phosphate-dehydrogenase deficiency is not recommended.
4. Dosage of Ofbeat
Dosage in adults:
Pneumonia, bronchitis severe illness due to infection: Oral in the morning, dose 400mg/day, when needed can be increased to 400mg every 12 hours/time, for 10 days. Chlamydia infection (ureter, cervix): Oral 400mg/day x 1 time or can be divided into small doses every 12 hours for 7 days. Gonorrhea, uncomplicated: Oral dose of 400mg x 1 single dose. Chronic prostatitis: Oral dose of 200mg, every 12 hours, for 28 days. Skin infections, soft tissue infections: Oral dose of 400mg, every 12 hours, for 10 days. Urinary tract infections: K. pneumoniae or E. coli cystitis: Oral dose of 200mg, every 12 hours, for 3 days. Cystitis caused by other strains of bacteria: 200mg orally every 12 hours for 7 days. Complicated urinary tract infections: Oral dose of 200mg, every 12 hours, for 10 days. Anthrax (Anthrax): 800mg/day in 2 divided doses, followed by 800mg/day in 2 divided doses, for 8 weeks. Adults with impaired renal function:
Creatinine clearance > 50ml/min: Dose as usual, every 12 hours. Creatinine clearance: 10 - 50ml/min: Dose as usual, every 24 hours. Creatinine clearance < 10 ml/min: Take 1⁄2 of the usual dose, every 24 hours. Children <18 years: Not recommended.
Elderly : It is necessary to adjust the dose for the elderly according to the degree of renal impairment.
5. Drug interactions
Antacids: Reduces absorption of Ofbeat. Anticoagulants: Risk of bleeding because Ofbeat enhances the effect of Acenocoumarol and Warfarin.. Oral iron, Sucralfate : Reduces absorption of Ofbeat.
6. Side effects encountered when using Ofbeat drug
Nausea, vomiting, abdominal pain, diarrhea, digestive disorders. Fatigue, headache, dizziness, visual disturbances, insomnia, hallucinations, depression,.. Rash, pruritus, vasculitis, Stevens-Johnson syndrome. The basic information about Ofbeat drug in the above article is for reference only. Because Ofbeat is a prescription drug, patients should not use it on their own, but need to contact a doctor or professional person directly to get an appropriate prescription, ensuring safety for health.
