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Ocemoca is a drug manufactured in the form of dispersible tablets, used to treat patients with uncontrolled primary hypertension with monotherapy. Dosage, indications and contraindications of the drug along with notes when using Ocemoca will be in the article below.1. What is Ocemoca?
Ocemoca is classified as a cardiovascular drug, used to treat primary hypertension in patients whose blood pressure is not controlled with monotherapy. The main ingredient of Ocemoca is Perindopril, an angiotensin-converting enzyme inhibitor.Ocemoca drug is produced in the form of dispersible tablets, packed in blisters of 10 tablets, the content in 1 Ocemoca tablet includes:
Perindopril in the form of Perindopril tert-butylamine 4mg. Indapamide 1.25mg
2. Uses of Ocemoca
As mentioned above, Ocemoca is used in the treatment of primary hypertension for patients whose blood pressure is not controlled with monotherapy. Perindopril is an inhibitor of the enzyme that converts Angiotensin I to Angiotensin II in plasma, causing vasoconstriction. In hypertensive patients, Ocemoca lowers blood pressure by reducing systemic peripheral resistance and dilating both arteries and veins.
The indapamide component in Ocemoca is a sulfonamide with diuretic and antihypertensive effects. Inpadamid in Ocemoca has the function of reabsorption of sodium + in the kidneys, increasing the excretion of sodium and chloride, leading to increased diuresis. In addition, Indapamide helps blood vessels to respond to amines vasoconstriction well, returning blood vessels to normal state, reducing peripheral small artery resistance.
Ocemoca drug is well absorbed orally, extensively metabolized in the liver and eliminated mainly in the urine.
3. Indications for taking Ocemoca
Ocemoca is used in the treatment of primary hypertension in patients whose blood pressure is not controlled with monotherapy.4. Contraindications to the use of Ocemoca
In the following cases, Ocemoca drug is contraindicated
Hypersensitivity to Perindopril contained in the drug; Hypersensitivity to Indapamide and sulfonamide derivatives; Patients with history of angioedema associated with the use of ACE inhibitors; People with cerebrovascular accident; Patients with anuria ; Patients with severe renal impairment have creatinine clearance less than 30ml/min; Children.
5. Dosage of Ocemoca
Dosage in hypertensive users: 1 Ocemoca tablet/time/day Dosage in renal failure: For patients with creatinine clearance > 60ml/min: Dose adjustment is not required. For patients with creatinine clearance between 30-60ml/min: Initiate with the recommended dose of 2mg/day (equivalent to half a tablet of Ocemoca, but not recommended for patients to break in half), should find another suitable dosage form. with dose. Dosage in the elderly: The starting dose depends on the patient's blood pressure response, especially when there is a loss of salt and water to avoid a sudden drop in blood pressure when starting the drug.
6. Ocemoca drug side effects
The listed side effects when taking Ocemora include:
Headache, the patient may become irritable, mood changes; Sleep disturbance, body weakness, easy dizziness; Loss of appetite, disturbance of taste; Skin rash; Dry cough, dry mouth; Decreased red blood cells, hyperkalemia, angioedema in the head, face and neck area.
7. Notes when using Ocemoca
In the following pathological cases, caution should be taken when using Ocemoca:
Patients with ischemia, heart failure, cerebrovascular disease, acute cardiac decompensation, myocardial hypertrophy, valve stenosis 2 leaves; Diabetic patients; Most diseased dehydration, volume depletion; Patients with cirrhosis, collagen vascular disease; Gout patients; Patients before, during and after major surgery; Patients with primary hyperaldosteronism ; Patients with liver failure, renal failure, renal artery stenosis; Patients on hemodialysis, renal vascular hypertension, congestive heart failure; Caution in the elderly; Pregnant or lactating women: there are no research documents on the use of Ocemoca on this subject, so do not arbitrarily use the drug without understanding its effects and without a doctor's appointment; Ocemoca can cause dizziness, drowsiness, so it is not recommended for people to operate machinery or drive. Ocemoca is a drug with 2 main ingredients including Perindopril and Indapamide, which is used to treat primary hypertension. The drug includes many side effects, when used with great care, should consult a doctor and monitor the effects after taking.
