This is an automatically translated article.
Nulesavir is a medicine used to treat chronic hepatitis B virus. The drug is available in the form of film-coated tablets. Dosage, usage and side effects of Nulesavir will be in the article below.1. What is Nulesavir?
Nulesavir is used in the treatment of chronic hepatitis B virus infection. Drugs administered to adults have evidence of viral replication activities and persistent elevations of serum aminotransferases (ALT or AST).
The main ingredient of Nulesavir is Entecavir as Entecavir monohydrate 1mg.
2. Uses of Nulesavir
Nulesavir drug has the main ingredient is Entecavir monohydrate, which inhibits the DNA polymerase of Hepatitis B Virus, thereby preventing this virus from growing and working. Entecavir is a synthetic drug derived from guanine with activity against hepatitis B virus. When entering the body, Nulesavir is phosphorylated by cellular enzymes to form entecavir triphosphate. This substance will compete with deoxyguanosin triphosphate to inhibit hepatitis B virus DNA polymerase.
3. Indications for taking Nulesavir
Nulesavir is used in the treatment of chronic hepatitis B virus infection in adults and children over 16 years of age with evidence that hepatitis B is actively replicating causing high blood DNA-HBV and multiple aminotransferase levels. serous .
4. Contraindications to taking Nulesavir
Some cases of hypersensitivity and the patient's health condition will be contraindicated to use Nulesavir as follows
Patients with a history of hypersensitivity to the entecavir component of the drug Nulesavir Pregnant and lactating women and children. children under 16 years old
5. Dosage & how to take Nulesavir
How to use: The drug is taken orally, taking the drug on an empty stomach, it is recommended to take it 2 hours after eating or 2 hours before the next meal.
Dosage:
For adults and children over 16 years old with chronic hepatitis B virus infection and have never used Nucleoside: 0.5mg/time/day (equivalent to half a Nulesavir tablet) For adults and children full 16 years of age with a history of hepatitis B virus infection when taking lamivudine: 1mg/time/day (equivalent to 1 Nulesavir tablet)
6. Nulesavir side effects
Side effects in hepatitis B drugs are something to be concerned about and understood by both doctors and patients. In Nulesavir, the main ingredient is Entecavir, so the common side effects are lactic acidosis and hepatomegaly and steatosis. These cases have been reported when patients used Nucleoside analogues alone or in combination with antiretroviral drugs. There have even been cases of hepatitis B getting worse when patients stopped taking anti-hepatitis B therapies, including treatment with Nulesavir.
7. Precautions when taking Nulesavir
To ensure the safety of patients when taking Nulesavir, it is necessary to monitor symptoms after taking the drug. Because the side effects of Nulesavir can also lead to death or worsening of the disease. Therefore, actively monitor liver function closely in patients receiving Nulesavir.
Nulesavir is a medicine for hepatitis B whose main ingredient is Entecavir. The drug is prepared in the form of tablets with the main ingredient of Entecavir monohydrate 1mg. When using Nulesavir for severe cases, it is necessary to be very careful and closely monitor to ensure safety for the patient.
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