Uses of Medoome 40mg

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1. What is Medoome 40mg?

Medoome 40mg medicine contains the main active ingredient Omeprazole 40mg, is made in the form of capsules, packaged in a box with 1 bottle of 28 tablets.

2. Effects of Medoome 40mg

2.1. Effects of Medoome 40mg Drug Medoome 40mg works on the terminal stage of acid secretion, a single daily dose of 20mg Omeprazole rapidly inhibits the secretion of services due to any stimulant. The active ingredient Omeprazole contained in Medoome 40mg has no other significant pharmacokinetic effects, besides it has no effect on histamine or acetylcholine receptors, except for an effect on acid secretion. The effect of Omeprazole causes a long-term decrease in gastric acid, but after that, 5 days after stopping Medoome 40mg, gastric secretion returned to normal, without an increase in acid secretion. The scar wall rate of duodenal ulcer was 65% after 2 weeks and 95% after 4 weeks of treatment when examined endoscopically.
2.2. Indications Medoome 40mg Medoome 40mg is indicated for use in the following cases:
Use Medoome 40mg on patients with gastroesophageal reflux syndrome - oesophagitis, Zollinger - Ellison syndrome. Medoome 40mg is indicated for the treatment of gastrointestinal ulcers such as active duodenal ulcer, progressive gastric ulcer. Treatment for esophagitis due to gastroesophageal reflux. 2.3. Contraindications Medoome 40mg Medoome 40mg is contraindicated for use in patients with hypersensitivity to the active ingredient Omeprazole or to Esomeprazole, other benzimidazole derivatives such as Pantoprazol, Lansoprazol, Rabeprazol or any of the excipients contained in the drug.

3. How to use and dose Medoome 40mg

3.1. How to use Medoome 40mg is produced in the form of capsules, when using, patients need to swallow the whole tablet, do not chew or crush the tablet.
3.2. Dosage The dose of Medoome 40mg depends on the type and condition of the disease. Dosage is for reference only, patients need to follow the instructions of the treating doctor to be suitable and effective during treatment:
Reduce symptoms of acid indigestion
Take a dose of 10 days or 20mg, lasts for 2 to 4 weeks.
Dosage used in the treatment of gastroesophageal reflux syndrome - oesophagitis
The usual dose, once a day, 20mg for 4 weeks, lasts for 4 to 8 weeks if the disease is not completely cured. In the case of patients with persistent esophagitis, a dose of 40 mg/day may be indicated. After the treatment has entered the recovery phase, the maintenance dose after esophagitis is 20mg, once a day, and for acid reflux is 10mg a day. Use Medoome 40mg to treat peptic ulcers
Single dose: 20mg daily, or 40mg daily in severe cases. Treatment lasts for 4 weeks for duodenal ulcers and for 8 weeks for patients with gastric ulcers. Use a maintenance dose of 10 to 20 mg once a day. Indicated in case of eradication of Helicobacter pylori in peptic ulcers
Combination of antibiotics with Omeprazole in dual or triple therapy.
Double therapy: Omeprazole used twice a day, 20mg once for 2 weeks. Triple therapy: Omeprazole twice daily, 20mg once for 1 week. Medoome 40mg is used in the treatment of NSAID-induced gastric ulcers 20mg daily, this dose can also be used for prophylaxis in patients with a history of gastrointestinal injury requiring continued treatment with NSAIDs.
Zollinger - Ellison syndrome
60mg once a day, the dose is adjusted as needed. Most patients are effectively controlled at doses ranging from 20 to 120 mg per day. However, it is still possible to use doses up to 120mg x 3 times/day. Doses above 80mg per day should be divided into 2 doses.
In addition, in the prevention of acid aspiration during general anesthesia, patients were given Medoome 40 mg at a dose of 40 mg the night before surgery and 2 to 6 hours before the procedure required an additional 40 mg.
Note: No need to adjust the dose for patients with impaired renal function, the elderly. Patients with hepatic impairment: use daily dose of 10-20mg. Currently, there are no recommendations for use in children.

4. Undesirable effects when using Medoome 40mg

Common side effects in patients taking Medoome 40mg such as: drowsiness, headache, dizziness, abdominal pain, nausea, vomiting, diarrhea, abdominal distension, constipation. Other less common side effects when using Medoome 40mg such as: confusion, insomnia, fatigue, dizziness, pruritus, urticaria, rash, reversible increase in transaminases. Rare side effects such as: peripheral edema, sweating, hypersensitivity including fever, angioedema, anaphylaxis, leukopenia, thrombocytopenia, agranulocytosis, reduction in all blood cell types. Agitation, reversible confusion, depression, hallucinations in elderly patients. Breast enlargement in men, dry mouth, gastritis, candidiasis, hepatic encephalopathy, hepatitis with or without jaundice, myalgia, arthralgia, bronchospasm, interstitial nephritis.

5. Drug Interactions Medoome 40mg

To avoid interactions Medoome 40mg should pay attention:
Do not use combination Atazanavir with proton pump inhibitors, if really necessary the combination must closely monitor the patient. Do not increase the dose of Omeprazole when combined, Atazanavir increased to 400mg, Ritonavir 100mg. Vitamin B12 may be reduced absorption when used with Medoome 40mg, so it is necessary to pay attention to the risk of Vitamin B12 deficiency in patients when using Medoome 40mg for a long time. Omeprazole is an inhibitor of CYP2C19, the potential for drug interactions with CYP2C19-metabolites should be taken into account after termination of treatment with Omeprazole. Omeprazole and Clopidogrel should not be used concomitantly.

6. Precautions for Medoome 40mg

During the use of Medoome 40mg, it should be noted:
When the patient has symptoms such as difficulty swallowing, prolonged vomiting, a lot of weight loss, vomiting blood or black stools, when there is suspicion or ulceration. stomach, the possibility of malignancy must be excluded, since treatment with Medoome 40 mg may provide symptomatic relief and delay diagnosis. Long-term use of Medoome 40mg for > 1 year and high doses may increase the risk of hip, spine, and wrist fractures, mainly in the elderly or in patients with other risk factors. Medoome 40mg is not recommended for pregnant women and nursing mothers. Patients who need to drive or operate machinery should be informed, because during the use of the drug may occur side effects such as visual disturbances and dizziness. Medoome medicine 40mg belongs to the group of gastrointestinal drugs, containing the main active ingredient is Omeprazole. The drug is prescribed by a doctor for a number of gastrointestinal diseases. To ensure effective treatment and avoid unwanted side effects, patients need to take the drug exactly as directed by a doctor or pharmacist.
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