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Sagaome drug is made in the form of lyophilized powder for injection with the main ingredient in each vial of 40mg Omeprazole in the form of Omeprazole sodium. So what does Sagaome drug work and how to use it?
1. Uses of Sagaome
The main ingredient of Sagaome drug is Omeprazole, which is an inhibitor of the enzyme system of Hydrogen-potassium Adenosine Triphosphatase, also known as the proton pump H + K + ATPase of gastric parietal cells.Omeprazole works at the end of acid secretion, a single dose of omeprazole 20mg/day causes rapid inhibition of gastric secretion due to any stimulus.
Omeprazole has no effect on acetylcholine or histamine receptors and it also has no significant pharmacokinetic effects other than on gastric acid secretion.
Omeprazole is a long-term, but reversible, reduction in gastric acid. Five days after discontinuation of the drug, gastric secretion returned to normal, but no hyperacidity was observed. On endoscopic examination, the scar wall rate of duodenal ulcer reached 65% after 2 weeks of treatment and up to 95% after 4 weeks.
Thanks to the main active ingredient, Sagaome is indicated in cases where the patient using oral drugs is not effective in the following diseases:
Stomach - duodenal ulcers Esophagitis with ulcers Zollinger's syndrome - Ellison. Sagaome drug is contraindicated in the following cases:
Patients with hypersensitivity to the drug components of Sagaome. Precautions when using Sagaome:
The possibility of malignancy should be excluded before treatment. Patients with severe liver disease: Use a dose of 20mg/day. Be careful when using Sagaome for pregnant women. Sagaome should not be used while breastfeeding.
2. Dosage and how to use Sagaome
Sagaome is used intravenously. Dilute 1 vial of Sagaome with 10 mL of solvent and administer intravenously slowly for not less than 2.5 minutes, at a rate not to exceed 4 mL/min.
The dose of Sagaome drug should be according to the doctor's instructions, the reference dose is as follows:
The usual dose is 40 mg/day. If further intravenous administration is required within 3 days, the dose should be reduced to 10-20 mg/day. Zollinger-Ellison syndrome requires dose adjustment of Sagaome according to the patient's response. No dose adjustment of Sagaome is required in patients with hepatic impairment, renal impairment and the elderly.
3. Side effects of the drug Sagaome
In the process of using Sagaome, you may encounter some side effects of the drug, including:
Headache Diarrhea Abdominal pain Nausea, vomiting Upper respiratory infection Dizziness Urticaria Constipation Cough Asthenia Backache. If you notice any unusual symptoms appearing while using Sagaome, you need to immediately notify your doctor for timely treatment.
4. Sagaome drug interactions with other drugs
Sagaome increases plasma concentrations of diazepam, phenytoin and warfarin when these drugs are used together. Therefore, patients need to inform the doctor about the drugs they are taking so that they can be considered and prescribed the right medicine.
Sagaome drug is prepared in the form of lyophilized powder for injection with the main ingredient in each vial of 40mg Omeprazole in the form of Omeprazole sodium. The drug is indicated for the treatment of certain diseases of the gastrointestinal tract. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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