This is an automatically translated article.
Mepraz drug is made in the form of capsules (containing enteric-coated microparticles), with the main ingredient being Omeprazole. The drug is indicated in the treatment of gastric ulcer, duodenal ulcer, gastroesophageal reflux disease, ... To ensure effective treatment, patients need to take the drug according to the instructions of a doctor, a specialist pharmacist. subject.
1. What does Mepraz do?
What disease does Mepraz treat? Mepraz medicine is made in the form of hard capsules, containing Omeprazole 20mg (so also known as Mepraz 20mg drug). Mepraz belongs to a new class of antisecretory agents, inhibiting the enzyme H+/K+ ATPase of gastric mucosal cells. Mepraz combines with the enzyme system H + / K + ATPase, and at the same time inhibits the final stage of acid production, effectively inhibiting acid secretion. Mepraz is indicated for use in the following cases:
Short-term treatment of progressive duodenal ulcer (not for maintenance treatment of patients with duodenal ulcer); Treatment of stomach ulcers; Treatment of gastro-oesophageal reflux: Long-term treatment of pathological hypersecretory conditions (polyendocrine tumors, Zollinger Ellison syndrome). Mepraz is contraindicated in the following cases:
People with hypersensitivity to the drug's components; Pregnant.
2. How to use and dose Mepraz 20 mg
How to use: Mepraz stomach medicine is taken orally, should be taken before eating. The patient should swallow the tablet whole, do not chew or crush the tablet.
Dosage:
Short-term treatment of active duodenal ulcer: Use dose 20mg/time/day for adults. Most patients heal within 4 weeks. Some cases may require an additional 4 weeks of treatment; Stomach ulcer: Use dose 20mg/time/day for 4-8 weeks; Severe erosive esophagitis or gastroesophageal reflux disease - oesophagitis respond poorly to treatment: Dose 20mg/time/day for 4-8 weeks for adults; Cases of pathological hypersecretion: Start with a dose of 60mg/time/day in adults. *Note: The dose of Mepraz should be adjusted according to the needs of each patient, the duration of treatment depends on the clinical response. Doses up to 120 mg 3 times/day may be used. For high doses above 80mg, it should be divided into smaller doses. No dosage adjustment is required in patients with renal impairment, liver dysfunction, the elderly,...
Overdose: When overdosage (up to 2400mg, 120 times the recommended clinical dose), the patient have symptoms of drowsiness, blurred vision, sensory disturbances, heart palpitations, nausea, vomiting, facial flushing, night sweats, dry mouth, headache,... For treatment, symptomatic treatment is required. symptoms and supportive treatment.
Missed dose: If a dose of Mepraz is missed, the patient should take it as soon as possible. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.
3. Mepraz side effects
When using Mepraz, patients may experience some unwanted side effects such as: Nausea, diarrhea, headache, constipation, flatulence and skin rash. In general, because Mepraz is well tolerated, side effects are rare. If the patient experiences the above symptoms, the patient should stop taking the drug and notify the doctor immediately or go to the nearest hospital for timely treatment.
4. Be careful when using Mepraz
Some notes for patients to remember when using Mepraz:
Symptomatic response when taking Mepraz does not exclude malignancy in the stomach; Mothers taking Mepraz should stop breastfeeding; Do not use Mepraz in pregnant women.
5. Meprazole drug interactions
Some drug interactions of Mepraz include:
When Mepraz is used in combination with some other drugs, it may affect the absorption of the drug (due to a decrease in acidity in the stomach). For example, absorption of ketoconazole is reduced when Mepraz is co-administered; Mepraz is metabolised in the liver by the cytochrome P450 enzyme system. Therefore, this drug may prolong the elimination time of warfarin, diazepam and phenytoin. However, concomitant use with Mepraz did not alter the blood concentrations of these drugs; Both Mepraz and clarithromycin concentrations were increased with concomitant use of these two drugs; Mepraz does not interact with food or other antacids when taken with them. During the course of using Mepraz, patients should strictly follow all the doctor's instructions. If there is any unusual symptom problem, the patient should immediately inform the doctor to get the appropriate advice.
Mepraz drug is made in the form of capsules (containing enteric-coated microparticles), with the main ingredient being Omeprazole. The drug is indicated in the treatment of gastric ulcer, duodenal ulcer, gastroesophageal reflux disease, ... To ensure effective treatment, patients need to take the drug according to the instructions of a doctor, a specialist pharmacist. subject.
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