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Maxlen 70 belongs to the group of osteoarthritis drugs, indicated in the treatment and prevention of osteoporosis in postmenopausal women, men... Let's learn about the uses and notes when using Maxlen 70 through the article. down here.
1. What is Maxlen 70?
Maxlen 70 contains the active ingredient Sodium Alendronate Trihydrate 91.37mg equivalent to Alendronic Acid 70mg. Alendronic acid is a bisphosphonate that inhibits osteoclast-mediated bone resorption without affecting bone formation. Preclinical studies have shown that alendronate preferentially binds to the site of actual destruction, inhibiting osteoclasts without affecting osteoclast involvement.
Maxlen 70 is indicated in the following cases:
Treatment and prevention of the risk of osteoporosis in postmenopausal women; Treatment of osteoporosis in men through the mechanism of increasing bone mass; Treatment of Glucocorticoid-induced osteoporosis in men and women; Treatment of bone deformities in men and women.
2. Dosage of the drug Maxlen 70
The recommended dosage of Maxlen 70 is as follows:
Adults: Take 1 tablet once a week; Elderly patients: No dose adjustment is required; Patients with renal failure: For patients with GFR over 35ml/min, no dose adjustment is required, for patients with GFR below 35ml/min, it is recommended not to use the drug due to lack of clinical experience; Children: The efficacy and safety of Alendronate in children have not been studied, so Maxlen 70 should not be used in the treatment of children. To achieve high therapeutic effect, patients should note a number of issues when taking Maxlen 70 as follows:
The drug should be taken 30 minutes before meals, or taken with filtered water or other beverages (including mineral water) and food may reduce the absorption of Alendronate; To reduce the risk of local irritation in the esophagus and facilitate the passage of the drug through the stomach, the patient should take the drug with a glass of water in the morning before getting up (at least 200ml); Patients should not chew or hold the tablet in their mouth to avoid the risk of mouth and throat ulcers; The patient should not lie down for 30 minutes after taking the drug; Do not take Maxlen 70 while lying in bed or before going to bed; Patients should supplement vitamin D and calcium in case the diet is not adequate.
3. Side effects
Maxlen 70 may cause some unwanted effects as follows:
Common: Headache, indigestion, abdominal pain, diarrhea, constipation, esophageal ulcer, difficulty swallowing, heartburn, abdominal distension, musculoskeletal pain; Uncommon: Vomiting, gastritis, mouth-throat ulcer, upper gastrointestinal bleeding ulcer, erythema, pruritus, rash; Rare: Symptoms of hypocalcaemia, hypersensitivity reactions, scleritis, uveitis, episcleritis, osteonecrosis of the jaw. Patients need to stop using and notify the doctor immediately if they experience unwanted effects when taking Maxlen 70.
4. Note when using
Contraindicated to use Maxlen 70 in the following cases:
Patients with abnormalities in the esophagus or agents that slow down esophageal emptying such as cardiac spasm, esophageal stricture; Person unable to sit upright or stand for at least 30 minutes; People who are sensitive to Alendronic Acid or any ingredient of Maxlen 70. Precautions for use:
Active ingredient Alendranic acid has the potential to irritate the upper gastrointestinal mucosa, so caution should be taken when using the drug. Maxlen 70 in patients with upper gastrointestinal disease such as peptic ulcer, dysphagia, recent history of serious gastrointestinal disease including gastrointestinal bleeding, gastrointestinal ulceration, surgery upper gastrointestinal surgery. There have been reports of side effects in the esophagus when taking Alendronic acid such as esophageal ulcer, esophagitis, esophagitis ... Therefore, patients should be closely monitored for symptoms signaling the esophagus such as irritation. reactions, difficulty swallowing, swallowing pain, heartburn... In case the above symptoms appear, the patient should stop using the drug and notify the treating doctor. The risk of side effects in the esophagus increases when the patient uses Alnedronat incorrectly, so the patient needs to be fully and specifically instructed on the dose and how to take Maxlen 70. The patient has many factors Risk factors such as chemotherapy, cancer, corticosteroid treatment, poor oral hygiene... should be examined before treatment with Maxlen. Patients should be corrected for hypocalcaemia before treatment with Alendronate. Because Alendronate increases bone mineral, it can lead to hypocalcaemia and phosphate. This condition is usually transient. For pregnant women, lactating women: Do not use Maxlen 70 in the treatment of these subjects. Store Maxlen at room temperature (below 30oC), avoid sunlight and high humidity.
5. Drug interactions
Using Maxlen 70 simultaneously with food, drinks (including mineral water), drugs to reduce stomach acid (Antacids), calcium supplements... will affect the absorption of Alendronate. Therefore, patients need to take Maxlen away from these drugs at least 30 minutes.
Studies of clinical significance have not been reported. Several studies testing the concurrent use of Maxlen 70 and Estrogen (vaginal, oral, subcutaneous) did not provide evidence of harmful effects.
Drug interactions occur that reduce the therapeutic effect of Maxlen 70, increasing the risk of unwanted effects. Therefore, the patient needs to inform the treating doctor about the drugs and supplements being used before treatment with Maxlen 70.
Above is information about the use, dosage and note when using. drug Maxlen 70. To ensure safety for your health and maximize the effectiveness of treatment, you need to take Maxlen 70 exactly as directed by your doctor.
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