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Lumigan medicine contains the active ingredient Bimatoprost 0.01%. This medication is used to treat IOP reduction in people with narrow-angle glaucoma or ocular hypertension. It is also used for another purpose, to increase the thickness, length, and darkness of eyelashes.
1. What does Lumigan do?
Lumigan medicine contains the main active ingredient Bimatoprost and other excipients in a sufficient amount. The drug is an eye drop with a strength of 3ml. It is indicated to reduce the increase in intraocular pressure in people with open-angle glaucoma or glaucoma.
Lumigan eye drops are contraindicated in people who are hypersensitive to Bimatoprost or to any of its ingredients.
2. Usage and dosage of Lumigan
Lumigan eye drops with the recommended therapeutic dose of 1 drop in the affected eye, the drug is used 1 time / day in the evening.
The therapeutic dose of Lumigan or bimatoprost 0.01% ophthalmic solution should not be exceeded once a day. The reason is that when repeatedly instilled Lumigan eye drops, Prostaglandin analogues reduce the effect of lowering intraocular pressure.
The decrease in intraocular pressure begins about 4 hours after the first instillation, maximum effect is achieved in about 8 to 12 hours.
If more than one type of eye drop is used, the drops must be spaced at least 5 minutes apart.
Information on overdose in humans is still available. If an overdose of Lumigan Bimatoprost 0.01% ophthalmic solution occurs, symptomatic treatment is required. If you miss a dose, you need to make up the dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. You should never take the medicine with double the prescribed dose.
3. Unwanted effects of the drug Lumigan
Lumigan eye drops may cause unwanted effects such as: itchy eyes, dry eyes, stinging eyes, eye pain or allergies, tearing eyes, headache ... In addition, Lumigan eye drops can causes discoloration of brown eyes and darkening of the skin around the eyes.
Lumigan can also make your eyelashes grow longer and thicker and darker. These changes are usually gradual. If you only use Lumigan eye drops in one eye there may be a difference between your eyes after taking bimatoprost. You should tell your treating doctor if you have any additional problems while using this medicine.
4. Interactions of the drug Lumigan
No studies on possible drug interactions: There are currently no studies demonstrating drug interactions in humans. This is because very low concentrations of Bimatoprost (less than 0.2 ng/ml) have been observed in systemic circulation after ocular instillation with a therapeutic dose of 0.01% Bimatoprost. Bimatoprost is biotransformed by multiple enzymes and pathways, and no effect on hepatic drug-metabolizing enzymes has been observed in preclinical studies in rats and monkeys. Lumigan ophthalmic solution has been used concomitantly with several eye drops with no evidence of drug interactions. Co-administration of Lumigan eye drops with non-beta-blocking glaucoma eye drops has not been evaluated in the treatment of glaucoma. IOP-lowering effect of prostaglandin analogues. For example, Lumigan eye drops may be reduced in people with glaucoma or glaucoma when used with other prostaglandin analogs.
5. Some notes when using Lumigan
Pigmentation: It has been reported that Lumigan eye drops alter pigment-containing tissues. The most frequently reported changes include increased pigmentation in the iris, periorbital or eyelid tissue, and eyelashes. Pigmentation is expected to increase when preparations containing the active ingredient Bimatoprost are still used. Eyelash changes: Lumigan eye drops can gradually change eyelashes and hair in the eyes being treated. These changes include increased length, increased thickness and number of eyelashes. Eyelash changes are usually reversible upon discontinuation of treatment with this drug. Inflammation in the eye: Lumigan eye drops should be used with caution in people with existing inflammation in the eye (such as keratitis). This is because inflammation can get worse. Bacterial Keratitis: There have been reports of bacterial keratitis associated with the use of multidose eye drops. Use when wearing contact lenses: Contact lenses must be removed before instilling Lumigan eye drops and 15 minutes after instillation and lenses can be worn again. Ability to drive and use machines: As with any eye drop preparation, if you experience transient blurred vision while instilling the medication, you should wait until your eyes are able to see clearly again first. while driving or using machinery.
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