Luxturna drug: Uses, indications and notes when using

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Luxturna is used to treat retinal dystrophy associated with biellelic RPE65 mutations. The main ingredient of Luxturna is Voretigene neparvovec-rzyl made from a certain virus that has been specially prepared. This treatment is called gene therapy.

1. How to use Luxturna

Your doctor may prescribe medication (such as prednisone) that you can take by mouth daily, starting 3 days before treatment for each eye, and continuing for 2 weeks after Luxturna injection. Carefully follow your doctor's directions for taking your medication(s).
Luxturna is injected into the affected eye(s) by a healthcare professional. Your doctor will treat each eye on separate days, at least 6 days apart. The eyes will be numbed before the injection. After the injection, you will stay in the hospital/clinic for a while, letting the doctor monitor your eyes and vision.
After leaving the hospital or clinic, try to lie down as much as possible for 24 hours after injecting Luxturna.
During the procedure, an air bubble will form in your eye. This bubble will slowly shrink over a week or so. You must not fly, climb or scuba dive until you are told that the air bubble in your eye has disappeared. A change in altitude while air bubbles are in your eye can cause permanent vision loss.
A small amount of the virus may be released from your tears and nose for a short time after the injection. Ask your doctor how to handle and remove waste from your eyes, tears, and nose for up to 7 days after your Luxturna injection.
Tell your doctor if your condition does not improve or if it gets worse after using Luxturna.

2. Side effects of the drug Luxturna

During treatment with Luxturna, you may experience mild discomfort or increased tear production may occur. If either of these side effects persist or get worse, tell your doctor right away.
Remember that your doctor has prescribed Luxturna because they have judged that the benefit to you outweighs the risk of side effects. Many people use Luxturna and no serious side effects occur.
Luxturna may rarely increase the risk of developing certain serious eye conditions such as cataracts, endophthalmitis, retinal tear/detachment. Tell your doctor right away if you notice any of the following symptoms in the affected eye(s): Pain, vision changes (such as decreased vision, blurred vision, flickering of light, see emerging water spots).
A very serious allergic reaction to Luxturna is very rare. However, if you notice any symptoms of a serious allergic reaction to Luxturna, including: Rash, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness It is important to get medical help right away.
Below are Luxturna side effects by likelihood.
Common side effects of Luxturna include:
A tear in the retina of the eye Glaucoma Glaucoma Corneal dystrophy, a deposition that forms in the cornea of ​​the eye. A hole in the yellow spot. Retinopathy Conjunctival congestion Eye pain Eye inflammation Eye irritation Uncommon Luxturna side effects include:
Inflammation of the inside of the eye This is not a complete list of Luxturna possible side effects. If you notice other side effects of Luxturna medicine not listed above, contact your doctor immediately for timely treatment.

3. Measures to prevent side effects of the drug Luxturna

Before using Luxturna, tell your doctor if you are allergic to this medicine and any other allergies you have. Luxturna products may contain inactive ingredients and they may cause allergic reactions or other problems..
Before using Luxturna, tell your doctor about your medical history, especially is about: Other eye conditions like cataracts, glaucoma.
Luxturna may cause blurred vision, so do not drive, use machines, or do anything that requires clear vision until you can safely do so.
Do not fly in airplanes, travel at high altitudes, or scuba dive until your doctor says you can do so.
Before surgery, tell your doctor or dentist that you are being treated with Luxturna.
For women during pregnancy, Luxturna should be used only when clearly needed. Discuss the risks and benefits of using Luxturna with your doctor.
It is not known if Luxturna passes into breast milk. Women who are breastfeeding should consult their doctor before using Luxturna.

4. Luxturna drug interactions

Drug interactions can change the way Luxturna works or increase the risk of serious side effects. Tell your doctor about all the medicines you use (including prescription/nonprescription drugs and herbal products). Do not start, stop, or change the dose of any medicine during treatment with Luxturna, without your doctor's approval.

5. What to do when overdose or forget to take Luxturna?

Overdose is unlikely with Luxturna as it is given by a healthcare professional. However, if you or someone else has overdosed on Luxturna and has severe symptoms such as fainting or difficulty breathing, call 911 immediately.
For the best possible benefit, it is important that you receive each dose of Luxturna according to the schedule directed by your doctor. If you miss a dose, contact your doctor to set up a new Luxturna dosing schedule.
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Reference source: webmd.com