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One of the classes of antibiotics used in the treatment of severe infections is Quinolone. In which Levin 500 contains the active ingredient Levofloxacin 500mg, which is commonly prescribed in the treatment of community-acquired pneumonia, acute sinusitis, urinary tract infections... Let's learn about its uses and notes. when using Levin 500 through the article below.
1. Uses of Levin 500
“What is Levin 500?”. Levin 500 contains the active ingredient Levofloxacin 500 - an antibiotic belonging to the Quinolone drug group. The bactericidal action of Levofloxacin is based on the mechanism of action on bacterial DNA replication through inhibition of the enzyme topoisomerase II or IV. Levofloxacin is a more potent antibiotic against gram-positive and anaerobic bacteria than other antibiotics in the same class. However, the effect on green pus bacillus (Pseudomonas aeruginosa) is weaker than that of ciprofloxacin.
Levin 500 is indicated in the following pathologies:
Acute sinusitis; Exacerbation of chronic bronchitis; Community-acquired pneumonia ; Urinary tract infections ; Skin and soft tissue infections.
2. Dosage of Levin 500
Levin 500 antibiotic belongs to a special control group, so the use of the drug should be prescribed by the treating doctor. Patients absolutely do not arbitrarily use the drug without a doctor's prescription, do not overdose or prolong the treatment time with Levin 500. Take the drug with a suitable amount of water during or after meals, do not chew or crush the tablet. Some recommendations on the dose of Levin 500 are as follows:
Treatment of pneumonia: The recommended dose of Levin 500 is to take 1 tablet/time x 1-2 times/day, duration of treatment is 1-2 weeks; Treatment of acute exacerbations of chronic bronchitis: The recommended dose of Levin 500 is to take 1 tablet/time/day for 7 days; Treatment of chronic prostatitis: The recommended dose of Levin 500 is to take 1 tablet/time/day for 10-14 days; Treatment of skin and soft tissue infections: The recommended dose of Levin 500 is to take 1 tablet/time/day for 7-10 days; Treatment and prevention of anthrax: The recommended dose of Levin 500 is 1 tablet/time/day, for 8 weeks of treatment; Patients with hepatic impairment do not require dose adjustment.
3. Side effects of Levin 500
Levin 500 may cause some side effects as follows:
Common: Diarrhea, nausea, insomnia, headache, increased liver enzymes; Uncommon: Dizziness, dizziness, anxiety, nervousness, flatulence, abdominal pain, dyspepsia, hyperbilirubinemia, vaginitis, Candida infection; Rare: Pseudomembranous colitis, hypertension, tendinitis, osteomyelitis, convulsions, depression, psychosis; In case of experiencing side effects, the patient should stop using Levin 500 and notify the treating doctor for timely treatment.
4. Note when using Levin 500
4.1. Contraindications Contraindicated to use Levin 500 in the following cases:
Patients with hypersensitivity to Levofloxacin, antibiotics of the Quinolone group or any ingredient of Levin 500; Patients with G6PD enzyme deficiency, epilepsy patients; Patients with a history of tendon disease caused by the use of the antibiotic Fuloroquinolone; Children under 18. 4.2. Precautions while using Levin 500 Phototoxic reactions have been reported in patients exposed to direct sunlight while being treated with Quinolone antibiotics. Therefore, patients should limit their exposure to sunlight during treatment with Levin 500.
During treatment with Levin 500, patients should periodically check the function of organs including liver, kidneys, blood-forming organs...
In patients with renal failure, the elimination rate of Levofloxacin is impaired, so patients need to adjust the dose of the drug in these subjects.
Use caution when using Levin 500 in patients with myasthenia gravis or with central nervous system diseases.
For pregnant women: Efficacy and safety of the drug in pregnant women have not been established. Therefore, do not use Levin 500 in the treatment of this subject.
For lactating women: There is not enough information on the excretion in breast milk of Levofloxacin, however other drugs of the Quinolone class are likely to be distributed into breast milk. Therefore, Levin 500 should not be used in lactating women.
Store the medicine at room temperature, away from light and high humidity.
5. Levin 500 drug interactions
Vitamins and minerals, antacids may reduce absorption of Levin 500 due to the risk of complexation between metal ions and Levofloxacin in the gastrointestinal tract.
Concomitant use of Levofloxacin and antidiabetic drugs may lead to a risk of dysglycemia.
Concomitant use of Levofloxacin and non-steroidal anti-inflammatory drugs (NSAIDs) may lead to nervous system effects and convulsions.
Drug interactions occur that reduce the therapeutic effect of Levin 500, increase the risk of unwanted effects. Therefore, patients need to inform the treating doctor about the drugs being treated (over-the-counter drugs, prescription drugs) and functional foods before being treated with Levin 500 to ensure safety and effectiveness when treating patients. treat.
The above are the uses of Levin 500, when using it, it is necessary to use it exactly as indicated for the drug to have the best effect. If you have any problems, you can talk to your doctor to improve your health.
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