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Evodhg 250 has the main active ingredient Levofloxacin and other excipients in a sufficient amount. This is a broad-spectrum synthetic antibiotic belonging to the fluoroquinolone group. The drug helps to treat bacterial infections, such as community-acquired pneumonia, chronic bronchitis,...
1. What is Evodhg 250?
Evodhg 250 belongs to the group of antibiotics for the treatment of parasitic diseases, anti-infectives, antivirals and antifungals. The drug is available in the form of a film-coated tablet. Packaging is a box of 3 blisters, each blister contains 10 tablets. The main active ingredient is Levofloxacin in the form of Levofloxacin hemihydrate 250mg and other excipients in sufficient quantities.2. Uses of Evodhg 250
Treatment of infections caused by bacteria sensitive to Levofloxacin antibiotics: Community-acquired pneumonia, prostatitis, skin infections.
Treatment of diseases related to urinary tract infections.
Treatment of acute bacterial exacerbations of chronic bronchitis
Acute bacterial sinusitis.
3. Usage and dosage of Evodhg 250
How to use: Use Evodhg 250 orally.
Dosage:
Treatment of respiratory tract infections: Community-acquired pneumonia: 500 mg dose, 1-2 times/day, for 7-14 days. Acute maxillary sinusitis: 500 mg, once a day, for 10 to 14 days. Treatment of uncomplicated skin and subcutaneous tissue infections: 500 mg once daily for 7 to 10 days. In case of complicated skin infections, use 750mg, once a day, for 7-14 days. Treatment of complicated urinary tract infections: 250mg, once a day, for 10 days. Treatment of acute pyelonephritis - pyelonephritis: 250mg, once a day, for 10 days. Treatment of uncomplicated urinary tract infections: 250mg once a day for 3 days. Treatment of acute exacerbations of chronic bronchitis: 500 mg once daily for 7 days. Acute bacterial sinusitis: 500 mg once daily for 10-14 days. In case of overdose: In case of overdose, the doctor will prescribe the drug out of the stomach and replace the fluid and monitor the electrocardiogram.
4. Undesirable effects of the drug Evodhg 250
Common adverse effects include nausea, diarrhea, increased liver enzymes, insomnia, headache, irritation at the injection site.
Uncommon side effects include dizziness, nervousness, agitation, anxiety, abdominal pain, bloating, dyspepsia, vomiting, constipation, hyperbilirubinemia, vaginitis, genital candidiasis, rash itching or rash.
Rare adverse effects: Increase or decrease in blood pressure, arrhythmias, myalgia, arthralgia, pseudomembranous colitis, dry mouth, convulsions, abnormal dreams, depression, psychosis anaphylactic shock.
Inform the treating doctor of the unwanted effects encountered when using the drug.
5. Drug interactions Evodhg 250
Antacids, sucralfate, metal ions, multivitamins can reduce the absorption of antibiotics Levofloxacin, should be taken at least 2 hours apart. The antibiotic Levofloxacin increases the effect of vitamin K antagonists (warfarin) and increases the risk of blood sugar disturbances when used. In addition to hypoglycemic agents, there is an increased risk of CNS excitability and convulsions when co-administered with non-steroidal anti-inflammatory drugs.
Calcium carbonate, digoxin, glibenclamide, ranitidine: The interaction is not clinically significant, so no dose adjustment of these drugs is required when co-administered with Evodhg 250.
Cyclosporin: The half-life of Cyclosporin was increased by 33% during concomitant treatment with the antibiotic Levofloxacin.
Caution should be exercised when levofloxacin is co-administered with drugs that affect renal tubular secretion such as probenecid and cimetidine, especially in patients with renal impairment.
Levofloxacin antibiotic reduces the effect of BCG, mycophenolate, sulfonylurea, typhoid vaccine.
6. Some notes when using Evodhg 250
6.1. Contraindications of the drug People who are sensitive or hypersensitive to the antibiotic components Levofloxacin and other quinolones or to any of the ingredients of the drug. People with epilepsy. People with G6PD deficiency. People with a history of tendon-related disease. Children under 18. Pregnant women and breastfeeding mothers. 6.2. Use with caution: Potentially irreversible and disabling serious adverse reactions to Evodhg 250, including tendinitis, tendon rupture, peripheral neuropathy, and neurological adverse effects central nervous system. Fluoroquinolone antibiotics have been associated with potentially fatal and irreversible adverse reactions in various body systems. Discontinue use at the first sign or symptom of any adverse health reaction. In addition, avoid the use of fluoroquinolone antibiotics in people who have experienced serious reactions related to fluoroquinolones. People with diseases related to the central nervous system such as epilepsy, cerebrovascular sclerosis... Evodhg 250 can cause pseudomembranous colitis caused by Clostridium difficile. It is important to note the accurate diagnosis of cases of diarrhea occurring while the patient is taking antibiotics to take appropriate measures. As with other quinolones, evodhg 250 may cause disturbances in glucose metabolism, including hyperglycemia or hypoglycemia, which often occur in diabetic patients receiving the antibiotic levofloxacin concurrently with an oral hypoglycemic agent. blood or with insulin; Therefore, it is necessary to monitor blood glucose in this patient. It should be avoided in patients with pre-existing prolongation of the QT interval, patients with hypokalemia, patients taking antiarrhythmic drugs of class IA (quinidine, procainamide...) or class III (sotalol, amiodarone..). .); Levofloxacin should be used with caution in patients with pre-arrhythmic conditions such as bradycardia and acute myocardial ischemia. For pregnant and lactating women: Do not use Levofloxacin antibiotic for pregnant women. For women who are breastfeeding, do not breast-feed while taking Evodhg 250. For machine operators or drivers: There is rarely an effect on the ability to drive and use machines. Hopefully, with the important information about Evodhg 250 medicine, it will help you better understand the mechanism of action, how to use it to ensure the best for the patient's health.
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