This is an automatically translated article.
Letrozole 2.5mg is a group of drugs indicated for the treatment of menopause or early breast cancer. So what is Letrozole 2.5mg and how should it be used? Knowing the information about the drug will help the medication process to be more effective.
1. What are the uses of Letrozole Stada 2.5mg?
1.1. What is Letrozole 2.5mg? Letrozole 2.5mg belongs to the group of anti-cancer drugs, aromatase inhibitors.
Letrozole Stada 2.5mg drug includes the following ingredients:
Main active ingredient: Letrozol 2.5mg Excipients: Lactose, microcrystallin cellulose, sodium starch glycolate, corn starch, magnesium stearate, hypromellose, HPC, talcum powder, cottonseed oil yellow iron oxide cloth, dd iron oxide, titanium dioxide. The drug is recommended for use in adults and the elderly.
1.2. What are the uses of Letrozole Stada 2.5mg? Letrozol is a non-steroidal aromatase enzyme inhibitor (inhibits oestrogen biosynthesis) and an antineoplastic agent.
Letrozole Stada 2.5mg is prescribed by doctors in the following cases:
Support treatment for postmenopausal women with hormone receptor positive early breast cancer. As an adjunct to the extended treatment of hormone-dependent early-stage breast cancer in postmenopausal women who have passed 5 years of baseline therapy with tamoxifen. First-line therapy for hormone-dependent advanced breast cancer in postmenopausal women. Treatment of advanced breast cancer after recurrence or advanced disease in women with natural or artificial menopause who have previously taken anti-estrogens. The effectiveness of the drug in patients with hormone receptor-negative breast cancer has not been established.
2. How to use Letrozole Stada 2.5mg
2.1. How to take Letrozole Stada 2.5mg Letrozole Stada 2.5mg is made in the form of tablets that should be taken orally Take with a sufficient amount of filtered water (warm water). The drug should be taken away from meals, because food slightly slows down the rate of drug absorption. Do not break, chew or crush, but swallow the whole tablet. To be sure, carefully read the instructions for use that come with the medicine. 2.2. Dosage of Letrozole Stada 2.5mg Adults and the Elderly: The recommended dose of Letrozole is 2.5 mg once daily.
In adjuvant therapy, Letrozol should be used continuously for 5 years or until the tumor recurs, whichever comes first. After a standard course of tamoxifen, treatment with Letrozol should be continued for 3 years or until the tumor recurs, whichever comes first.
Since there is not enough data for long-term use, there is no optimal usage time.
In patients with metastatic breast cancer, letrozol is administered continuously until tumor progression becomes evident.
Preoperative treatment: regularly check the progress of the disease. No dose adjustment is required for the elderly. Patients with hepatic and/or renal impairment No dosage adjustment is required for patients with mild or moderate hepatic impairment.
No dosage adjustment is required for patients with renal impairment (creatinine clearance ≥ 10 ml/min).
3. Contraindications of Letrozole Stada 2.5mg
Patients who are allergic to the main ingredient Letrozole or any of the excipients listed above of the drug Letrozole Stada 2.5mg
Letrozole Stada 2.5mg is contraindicated for women who are in the perimenopausal period, are pregnant and breastfeeding.
Patients with severe liver failure.
Do not use Letrozol before surgery if receptor status is negative or unknown.
4. Notes when using Letrozole Stada 2.5mg
For female patients with no obvious post-menopausal symptoms, FSH, LH or estradiol levels should be assessed before starting treatment to accurately determine post-menopausal status. of the patient.
Letrozol has not been studied in patients with clearance <30 ml/min to date. Currently, the Letrozol studies are limited to a limited number of women with non-metastatic cancer and varying degrees of liver disease: mild to moderate and severe hepatic impairment.
Letrozole Stada 2.5mg significantly reduces estrogen levels in patients. The median duration observed during 30 months of adjuvant therapy and 39 months of extended support was not sufficient to assess fracture risk associated with long-term Letrozole Stada 2.5 mg use.
Women with a history of osteoporosis, fracture, or at risk of osteoporosis should undergo a bone density assessment before initiating adjuvant or extended adjuvant therapy. These women should be monitored for osteoporosis during and after treatment with Letrozole Stada 2.5mg.
Patients with hereditary galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
5. Side effects of the drug Letrozole Stada 2.5mg
Very common:
Excessive sweating Joint pain Face flushing, fatigue, weakness. Common:
Weight gain Headache, dizziness Nausea, vomiting, indigestion, constipation, diarrhea. Hair loss, rash, erythema, you have maculopapular, you have psoriasis and you have blisters. Osteoporosis, fracture, bone pain, muscle pain Anorexia, hypercholesterolemia, increased appetite Peripheral edema, irritability Depression. The above are important notes when using Letrozole Stada 2.5mg if there are any additional questions, patients should discuss directly with the treating doctor for accurate advice.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
