This is an automatically translated article.
Jinvasta is a cardiovascular drug, treating cases of atherosclerosis, cardiovascular disease, dyslipidemia. To learn more about the use of the drug, how to use it, you can refer to the following article.
1.Ingredients of Jinvasta
Jinvasta drug has the following main ingredients:
Simvastatin : 20mg Other excipients just enough The drug is made in the form of film-coated tablets. Packed in a box of 3 blisters, each blister of 10 tablets.
2.Effects of Jinvasta
Jinvasta has the main active ingredient is Simvastatin, so the effect of Jinvasta is also the effect of Simvastatin. This is a blood fat-lowering drug, specifically lowering the cholesterol index.
Cholesterol is synthesized from a fermentation product of Aspergillus terreus, the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, which catalyzes the conversion of HMG-CoA to mevalonate, rate-limiting step and the first step in cholesterol biosynthesis.
So what is the main mechanism of action of Simvastatin? Simvastatin is a specific inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate which is the first step in cholesterol biosynthesis. In addition, Simvastatin reduces cholesterol levels, low density (LDL) at normal and when elevated. The mechanism of the LDL-lowering action of simvastatin may be due to decreased VLDL cholesterol levels and induction of LDL receptors, leading to decreased production and/or increased allergenicity of LDL cholesterol.
3. Indications for taking Jinvasta
Jinvasta is used as a dietary supplement in patients with primary hypercholesterolemia caused by elevation of low-density lipoprotein cholesterol (LDL). The drug is an adjunct in the treatment of patients at risk for coronary artery disease who do not respond to diet. In addition, Jinvasta is also used to reduce low-density lipoprotein (LDL) cholesterol levels in patients with both hypercholesterolemia and hypertriglyceridemia.4.How to use and dosage Jinvasta
How to use:
Jinvasta is in the form of tablets, so the drug is used orally. The drug should be taken after meals with a full glass of filtered water, do not drink Jinvasta with fruit juices or other water preparations that will lose the effect of the drug. In parallel with taking Jinvasta, patients need to use a cholesterol-lowering diet in the diet combined with exercise for at least 30 minutes a day. Dosage:
The starting dose is 1 tablet/time/day, taken after dinner. The maximum dose is 40mg/day. Dosage is for reference only, the specific dose depends on the patient's condition, disease progression and dose adjustment depending on the patient's response.
5. Be careful when using Jinvasta
Simvastatin active ingredient in Jinvasta can increase serum transaminase and creatinine phospholinase levels, so care should be taken when differential diagnosis of patients with chest pain during treatment. During the use of Jinvasta, patients need to be monitored for liver function, because oral drugs affect liver function. During the use of Jinvasta, if the patient has unexplained muscle pain or weakness, immediately notify the doctor. Do not drink alcohol when taking Jinvasta Be careful when using the drug for children because there are no studies on safety and effects on this subject.
6.Contraindications to taking Jinvasta
Jinvasta is contraindicated in the following cases:
Patients who are allergic or have hypersensitivity reactions to any of the components of the drug Progressive liver dysfunction Frequent increase in blood transaminemia, unknown cause core. Pregnant women Breastfeeding women
7. Interaction of Jinvasta with other drugs
The drugs cyclosporin, erythromycin, gemfibrozil, itraconazole, ketoconazole or with niacin when combined with Jinvasta often cause myositis and rhabdomyolysis. The effect of warfarin will be increased when taken with Jinvasta. During the use of Jinvasta, there may be interactions between drugs or between the drug and food or other health-protective foods. This will affect the effect and effectiveness of the drug, so to avoid adverse interactions, patients should provide their doctor with all prescription and non-prescription medications before taking Jinvasta. .
8.Side effects of the drug Jinvasta
During the course of taking Jinvasta, the patient may experience undesirable effects such as:
Flatulence, Diarrhea, Constipation, Nausea, If the patient experiences any symptoms during the use of Jinvasta, please notify the doctor immediately. any discomfort.
9. Overdose when taking Jinvasta
There have been reports of Simvastatin overdose, however, none of the patients had special symptoms and all patients recovered without sequelae.
In case the patient uses jinvasta drug overdose, it is necessary to notify the doctor for symptomatic treatment and support when necessary. Because jinvasta is strongly bound to plasma proteins, hemodialysis is not expected to significantly increase statin clearance.
In summary, Jinvasta is a drug to treat lipid metabolism disorders, which has the effect of lowering blood fat, especially cholesterol. Patients should take the drug when prescribed by the doctor to monitor how the drug response is responding. If you have any questions regarding Jinvasta, please contact your doctor immediately for answers.
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