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Fudall 10mg is often prescribed by doctors to treat chronic hepatitis B. In order to use the drug effectively, patients need to learn some information about the uses, dosage and notes when using Fudall 10mg in the article below.
1. What is Fudall 10mg?
Fudall 10mg contains the main ingredient Adefovir dipivoxil, which is a prodrug of Adefovir in oral form. This is a reverse transcriptase inhibitor similar to Acyclic Nucleoside Phosphonate.
Active ingredient Adefovir dipivoxil when entering the human body will be transported into the cells inside. From there, it will be converted by cellular enzymes into the form of Adefovir diphosphate. When this process occurs, the drug will be able to compete with reverse transcriptase polymerase to bind to the natural substrate. Next, Adefovir diphosphate binds to viral DNA, terminating DNA synthesis.
Thanks to the above process, Adefovir dipivoxil is able to inhibit HBV DNA reverse transcriptase. As a result, Fudall 10mg is effective in treating hepatitis B in some cases.
2. Indications and contraindications Fudall 10mg
Fudall drug 10mg is indicated in the treatment of chronic hepatitis B in people over 18 years of age who are evaluated for viral replication, increased Aminotransferase (ALT, AST) in serum or histopathology.
The drug is contraindicated in patients with hypersensitivity to Adefovir dipivoxil and other ingredients contained in the drug.
3. Dosage and how to take Fudall 10mg
Depending on the patient's case, Fudall 10mg users will have certain differences.
Dosage for adults: Use the drug with the recommended dose of 1 tablet / time x 1 time / day. Patients with impaired renal function: In this subject, it is necessary to adjust the dose or the interval between the doses of Fudall 10mg depending on the patient's creatinine clearance. In case of creatinine clearance above 50ml/min the patient can take the usual dose. However, for patients with a creatinine clearance of 20-49ml/min, it is important to note that the doses are given 48 hours apart. Particularly for Creatinine clearance from 10-19ml/min, it is necessary to pay attention to the oral doses 72 hours apart. People on hemodialysis: Use the drug after 7 days when hemodialysis is completed or the cumulative dialysis time is 12 hours. Fudall 10mg is a drug that is made in tablet form so you can take it orally. You can use filtered or boiled water when taking the medicine, make sure to take the correct dose as prescribed by the treating doctor.
During the course of taking the drug, the patient absolutely should not stop or change the dose without consulting the doctor.
4. Fudall 10mg . side effects
Fudall 10mg drug has the potential to cause some side effects when used such as:
Digestive disorders, abdominal pain, flatulence, diarrhea, nausea. Affects the nervous system causing weakness, headache, headache. Patients may have sinusitis, pharyngitis, cough. Tests found elevated liver enzyme levels, increased serum creatinine, kidney damage, acute renal failure. In the process of using Fudall 10mg, if you see any unwanted effects, the patient should notify the doctor, especially serious side effects for timely treatment.
5. Drug interactions
Fudall 10mg has the potential to interact with some of the following drugs:
Coadministration with drugs that are actively secreted by the renal tubules may increase serum concentrations of both drugs. Concomitant use with nephrotoxic drugs may aggravate nephrotoxicity. To avoid drug interactions that affect the effectiveness of your treatment, tell your doctor about all medications you are taking.
6. Some notes when using Fudall 10mg
For patients using Fudall 10mg for a long time, it is necessary to check liver and kidney function every 3 months. Use caution when using the drug for subjects at risk of liver disease. Especially when using the drug, if the liver is enlarged and fatty, the patient should stop taking Fudall 10mg. If the drug is given to HIV patients, it is necessary to check for HIV antibodies before starting treatment. The drug should be stored in a closed container, in a cool place, at a temperature below 25 degrees Celsius, protected from light and out of the reach of children. The drug can be used for people who are driving or operating machinery because the drug does not affect the nervous system or cause drowsiness. If the drug is overdosed, the patient may show signs of stomach pain, vomiting, loose stools, loss of appetite. At this point, the patient needs to be taken to the emergency room at a medical facility immediately. If you miss a dose of Fudall 10mg, you should take it as soon as you remember for the day. However, if it is almost time for your next dose, you can skip it instead of taking a double dose, which can have serious consequences. Above is some information about Fudall 10mg drug. This product will promote the highest effectiveness when users use it correctly, following the instructions from a specialist.
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